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TG elisa kit :: Human Thyroglobulin ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2887201
Typical Standard Curve/Testing Data
Unit / Price
48-Strip-Wells  /  $380 +1 FREE 8GB USB
96-Strip-Wells  /  $500 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,170 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,840 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Thyroglobulin (TG), ELISA Kit

★Popular Item★
 Also Known As   

Human Thyroglobulin ELISA Kit

 Product Synonym Names    Thyroglobulin; Tg; TG
 Product Gene Name   

TG elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS2887201 Testing Data    Testing Data PDF
 OMIM    188450
 3D Structure    ModBase 3D Structure for P01266
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 Species Reactivity    Human
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 Assay Type    Sandwich
 Detection Range    1.25-80 ng/mL
 Sensitivity    0.3 ng/mL
 Intra-Assay CV    <=3.5%
 Inter-Assay CV    <=7.9%
 Recovery    87%
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 Preparation and Storage    For long term storage, please store the entire kit at -20 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TG elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TG purchase    MBS2887201 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Thyroglobulin (TG) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 1.25-80 ng/mL in biological research samples containing TG, with an estimated sensitivity of 0.3 ng/mL. The ELISA analytical biochemical technique of the MBS2887201 kit is based on TG antibody-TG antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TG antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TG. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for TG elisa kit

   Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids.

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.
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 Typical Standard Curve/Testing Data of TG elisa kit    TG elisa kit Typical Standard Curve/Testing Data image
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Sample Manual Insert of MBS2887201. Click to request current manual
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NCBI/Uniprot data below describe general gene information for TG. It may not necessarily be applicable to this product.
 NCBI GI #    55770862
 NCBI GeneID    7038
 NCBI Accession #    NP_003226.4 [Other Products]
 NCBI GenBank Nucleotide #    NM_003235.4 [Other Products]
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 UniProt Primary Accession #    P01266 [Other Products]
 UniProt Secondary Accession #    O15274; O43899; Q15593; Q15948; Q9NYR1; Q9NYR2; Q9UMZ0; Q9UNY3 [Other Products]
 UniProt Related Accession #    P01266 [Other Products]
 Molecular Weight    298,383 Da
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 NCBI Official Full Name    thyroglobulin
 NCBI Official Synonym Full Names    thyroglobulin
 NCBI Official Symbol    TG [Similar Products]
 NCBI Official Synonym Symbols   
TGN; AITD3
[Similar Products]
 NCBI Protein Information    thyroglobulin
 UniProt Protein Name    Thyroglobulin
 Protein Family    Thyroglobulin
 UniProt Gene Name    TG [Similar Products]
 UniProt Synonym Gene Names    Tg [Similar Products]
 UniProt Entry Name    THYG_HUMAN
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 NCBI Summary for TG    Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009]
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 UniProt Comments for TG    TG: Precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Defects in TG are the cause of thyroid dyshormonogenesis 3 (TDH3). A disorder due to thyroid dyshormonogenesis, causing large goiters of elastic and soft consistency in the majority of patients. Although the degree of thyroid dysfunction varies considerably among patients with defective thyroglobulin synthesis, patients usually have a relatively high serum free triiodothyronine (T3) concentration with disproportionately low free tetraiodothyronine (T4) level. The maintenance of relatively high free T3 levels prevents profound tissue hypothyroidism except in brain and pituitary, which are dependent on T4 supply, resulting in neurologic and intellectual defects in some cases. Variations in TG are associated with susceptibility to autoimmune thyroid disease type 3 (AITD3). AITDs including Graves disease (GD) and Hashimoto thyroiditis (HT), are among the most common human autoimmune diseases. They are complex diseases, which are caused by an interaction between susceptibility genes and nongenetic factors, such as infection. Belongs to the type-B carboxylesterase/lipase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 8q24

Cellular Component: endoplasmic reticulum; extracellular region; extracellular space; Golgi apparatus; perinuclear region of cytoplasm; protein complex

Molecular Function: anion binding; chaperone binding; hormone activity; protein complex binding; protein homodimerization activity

Biological Process: hormone biosynthetic process; iodide transport; regulation of myelination; response to lipopolysaccharide; response to pH; signal transduction; thyroid gland development; thyroid hormone metabolic process; transcytosis

Disease: Autoimmune Thyroid Disease, Susceptibility To, 3; Thyroid Dyshormonogenesis 3
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 Research Articles on TG    1. In the diagnosis of lymphatic metastasis in papillary thyroid carcinoma, FNA-Tg levels in the preoperative state are affected by serum Tg levels when they exceeded 1.0 mug/L.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TG elisa kitPathways associated with TG elisa kit
 Reference Product  PubMed Publications
 TPO elisa kit  >668 publications with TG and TPO
 TSHR elisa kit  >134 publications with TG and TSHR
 ALB elisa kit  >122 publications with TG and ALB
 INS elisa kit  >122 publications with TG and INS
 NKX2-1 elisa kit  >21 publications with TG and NKX2-1
 HSPA5 elisa kit  >10 publications with TG and HSPA5
 HHEX elisa kit  >3 publications with TG and HHEX
 LRP2 elisa kit  >3 publications with TG and LRP2
 Products by Pathway  Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Thyroid Hormone Synthesis Pathway antibodies  Thyroid Hormone Synthesis Pathway Diagram
 Thyroid Hormone Synthesis Pathway antibodies  Thyroid Hormone Synthesis Pathway Diagram
 Thyroxine (Thyroid Hormone) Production Pathway antibodies  Thyroxine (Thyroid Hormone) Production Pathway Diagram
Diseases associated with TG elisa kitOrgans/Tissues associated with TG elisa kit
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >5145 publications with TG and Cardiovascular Diseases
 Thyroid Diseases Antibodies  >2547 publications with TG and Thyroid Diseases
 Fatty Liver Antibodies  >1890 publications with TG and Fatty Liver
 Inflammation Antibodies  >1727 publications with TG and Inflammation
 Liver Diseases Antibodies  >1667 publications with TG and Liver Diseases
 Hypertension Antibodies  >1510 publications with TG and Hypertension
 Thyroid Neoplasms Antibodies  >1283 publications with TG and Thyroid Neoplasms
 Necrosis Antibodies  >983 publications with TG and Necrosis
 Kidney Diseases Antibodies  >872 publications with TG and Kidney Diseases
 Goiter Antibodies  >660 publications with TG and Goiter
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >17524 publications with TG and Blood
 Liver Antibodies  >4403 publications with TG and Liver
 Thyroid Antibodies  >3325 publications with TG and Thyroid
 Muscle Antibodies  >2479 publications with TG and Muscle
 Brain Antibodies  >2448 publications with TG and Brain
 Kidney Antibodies  >1384 publications with TG and Kidney
 Connective Tissue Antibodies  >1162 publications with TG and Connective Tissue
 Lymph Node Antibodies  >740 publications with TG and Lymph Node
 Intestine Antibodies  >642 publications with TG and Intestine
 Pancreas Antibodies  >502 publications with TG and Pancreas
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