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TFPI elisa kit :: Human Tissue Factor Pathway Inhibitor ELISA Kit

Scan QR to view Datasheet Catalog #    MBS024139 TFPI elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Tissue Factor Pathway Inhibitor (TFPI), ELISA Kit

 Also Known As   

Human Tissue Factor Pathway Inhibitor ELISA Kit

 Product Gene Name   

TFPI elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 Chromosome Location    Chromosome: 2; NC_000002.11 (188328957..188419219, complement). Location: 2q32
 OMIM    152310
 3D Structure    ModBase 3D Structure for P10646
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 Species Reactivity    Human
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Other Notes    Small volumes of TFPI elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TFPI purchase    MBS024139 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Tissue Factor Pathway Inhibitor (TFPI) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TFPI. The ELISA analytical biochemical technique of the MBS024139 kit is based on TFPI antibody-TFPI antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TFPI antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TFPI. Appropriate sample types may include undiluted human body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for TFPI. It may not necessarily be applicable to this product.
 NCBI GI #    73760409
 NCBI GeneID    7035
 NCBI Accession #    NP_001027452.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001032281.2 [Other Products]
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 UniProt Primary Accession #    P10646 [Other Products]
 UniProt Secondary Accession #    O95103; Q53TS4 [Other Products]
 UniProt Related Accession #    P10646 [Other Products]
 Molecular Weight    35,015 Da
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 NCBI Official Full Name    tissue factor pathway inhibitor isoform b
 NCBI Official Synonym Full Names    tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
 NCBI Official Symbol    TFPI [Similar Products]
 NCBI Official Synonym Symbols   
EPI; TFI; LACI; TFPI1
[Similar Products]
 NCBI Protein Information    tissue factor pathway inhibitor; anti-convertin; extrinsic pathway inhibitor
 UniProt Protein Name    Tissue factor pathway inhibitor
 UniProt Synonym Protein Names   
Extrinsic pathway inhibitor; EPI; Lipoprotein-associated coagulation inhibitor
 Protein Family    Tissue factor pathway inhibitor
 UniProt Gene Name    TFPI [Similar Products]
 UniProt Synonym Gene Names    LACI; TFPI1; TFPI; EPI; LACI [Similar Products]
 UniProt Entry Name    TFPI1_HUMAN
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 NCBI Summary for TFPI    This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed. [provided by RefSeq, Jul 2008]
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 UniProt Comments for TFPI    TFPI: Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, GPI anchor; Secreted; Inhibitor; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 2q32

Cellular Component: extracellular space; cell surface; endoplasmic reticulum; plasma membrane; extracellular region

Molecular Function: serine-type endopeptidase inhibitor activity; endopeptidase inhibitor activity

Biological Process: blood coagulation, extrinsic pathway; blood coagulation
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 Research Articles on TFPI    1. TFPI inhibited MCP-3 expression induced by TNF-alpha; this effect may be propagated through the NF-kappaB/IkappaB-alpha pathway.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TFPI elisa kitPathways associated with TFPI elisa kit
 Reference Product  PubMed Publications
 FGF2 elisa kit  >11 publications with TFPI and FGF2
 F10 elisa kit  >2 publications with TFPI and F10
 SERPINC1 elisa kit  >1 publications with TFPI and SERPINC1
 SDC4 elisa kit  >1 publications with TFPI and SDC4
 Products by Pathway  Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Extrinsic Pathway antibodies  Extrinsic Pathway Diagram
 Formation Of Fibrin Clot (Clotting Cascade) Pathway antibodies  Formation Of Fibrin Clot (Clotting Cascade) Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Integrated Breast Cancer Pathway antibodies  Integrated Breast Cancer Pathway Diagram
 Syndecan-4-mediated Signaling Events Pathway antibodies  Syndecan-4-mediated Signaling Events Pathway Diagram
Diseases associated with TFPI elisa kitOrgans/Tissues associated with TFPI elisa kit
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >517 publications with TFPI and Cardiovascular Diseases
 Inflammation Antibodies  >188 publications with TFPI and Inflammation
 Neoplasms Antibodies  >183 publications with TFPI and Neoplasms
 Venous Thrombosis Antibodies  >124 publications with TFPI and Venous Thrombosis
 Necrosis Antibodies  >77 publications with TFPI and Necrosis
 Disease Models, Animal Antibodies  >73 publications with TFPI and Disease Models, Animal
 Carcinoma Antibodies  >72 publications with TFPI and Carcinoma
 Myocardial Infarction Antibodies  >64 publications with TFPI and Myocardial Infarction
 Kidney Diseases Antibodies  >57 publications with TFPI and Kidney Diseases
 Pain Antibodies  >37 publications with TFPI and Pain
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1198 publications with TFPI and Blood
 Vascular Antibodies  >520 publications with TFPI and Vascular
 Embryonic Tissue Antibodies  >100 publications with TFPI and Embryonic Tissue
 Muscle Antibodies  >95 publications with TFPI and Muscle
 Lung Antibodies  >84 publications with TFPI and Lung
 Heart Antibodies  >81 publications with TFPI and Heart
 Kidney Antibodies  >79 publications with TFPI and Kidney
 Liver Antibodies  >75 publications with TFPI and Liver
 Umbilical Cord Antibodies  >46 publications with TFPI and Umbilical Cord
 Placenta Antibodies  >45 publications with TFPI and Placenta
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