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TGM6 elisa kit :: Human Transglutaminase-6 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2533332
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Transglutaminase-6 (TGM6), ELISA Kit

★Popular Item★
 Also Known As   

Human TGM6 (Transglutaminase-6) ELISA Kit

 Product Gene Name   

TGM6 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    613900
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 Species Reactivity    Human
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 Specificity    This kit recognizes natural and recombinantHumanTGM6. No significant cross-reactivity or interference between HumanTGM6 and analogues was observed.
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 Samples    Serum, plasma and other biological fluids
 Assay Type    Quantitative Sandwich
 Detection Range    1.563-100mIU/mL
 Sensitivity    0.938mIU/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TGM6 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TGM6 purchase    MBS2533332 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Transglutaminase-6 (TGM6) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 1.563-100mIU/mL in biological research samples containing TGM6, with an estimated sensitivity of 0.938mIU/mL. The ELISA analytical biochemical technique of the MBS2533332 kit is based on TGM6 antibody-TGM6 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TGM6 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TGM6. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for TGM6 elisa kit

   Intended Uses: This ELISA kit applies to the invitro quantitative determination of HumanTGM6concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to TGM6. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for TGM6and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain TGM6, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of TGM6.You can calculate the concentration of TGM6in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of TGM6 elisa kit    TGM6 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2533332. Click to request current manual
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NCBI/Uniprot data below describe general gene information for TGM6. It may not necessarily be applicable to this product.
 NCBI GI #    119631005
 NCBI GeneID    343641
 NCBI Accession #    EAX10600.1 [Other Products]
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 UniProt Secondary Accession #    Q5JXU4; Q5JXU5; Q719M2; Q719M3; Q9Y4U8 [Other Products]
 UniProt Related Accession #    O95932 [Other Products]
 Molecular Weight    70,516 Da
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 NCBI Official Full Name    transglutaminase 6, partial
 NCBI Official Synonym Full Names    transglutaminase 6
 NCBI Official Symbol    TGM6 [Similar Products]
 NCBI Official Synonym Symbols   
TG6; TGY; SCA35; TGM3L; dJ734P14.3
[Similar Products]
 NCBI Protein Information    protein-glutamine gamma-glutamyltransferase 6
 UniProt Protein Name    Protein-glutamine gamma-glutamyltransferase 6
 UniProt Synonym Protein Names   
Transglutaminase Y; TGY; TGase Y; Transglutaminase-3-like; TGase-3-like; Transglutaminase-6; TG6; TGase-6
 Protein Family    Protein-glutamine gamma-glutamyltransferase
 UniProt Gene Name    TGM6 [Similar Products]
 UniProt Synonym Gene Names    TGM3L; TGY; TGase Y; TGase-3-like; TG6; TGase-6 [Similar Products]
 UniProt Entry Name    TGM3L_HUMAN
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 NCBI Summary for TGM6    The protein encoded by this gene belongs to the transglutaminase superfamily. It catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Mutations in this gene are associated with spinocerebellar ataxia type 35 (SCA35). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
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 UniProt Comments for TGM6    TGM6: an enzyme of the transglutaminase family that catalyzes the crosslinking of proteins and the conjugation of polyamines to proteins. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. Two alternatively spliced isoforms have been described.

Protein type: EC 2.3.2.13; Transferase

Chromosomal Location of Human Ortholog: 20p13

Cellular Component: cytoplasm

Molecular Function: metal ion binding; protein-glutamine gamma-glutamyltransferase activity

Biological Process: peptide cross-linking

Disease: Spinocerebellar Ataxia 35
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 Research Articles on TGM6    1. TGM6 missense mutation cosegregated with AML in a large family.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with TGM6 elisa kit
 Disease Name  Pubmed Publications
 Neuromuscular Diseases Antibodies  >1 publications with TGM6 and Neuromuscular Diseases
 Growth Disorders Antibodies  >1 publications with TGM6 and Growth Disorders
 Atrophy Antibodies  >1 publications with TGM6 and Atrophy
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