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TUBb3 elisa kit :: Human Tubulin Beta 3 (TUBb3) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9309384 TUBb3 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,575 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,055 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Tubulin Beta 3 (TUBb3), ELISA Kit

 Also Known As   

Human Tubulin Beta 3 (TUBb3) ELISA Kit

 Product Gene Name   

TUBb3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 Chromosome Location    Chromosome: 16; NC_000016.10 (89922009..89936097). Location: 16q24.3
 OMIM    600638
 3D Structure    ModBase 3D Structure for Q13509
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Other Notes    Small volumes of TUBb3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TUBb3 purchase    MBS9309384 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Tubulin Beta 3 (TUBb3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TUBb3. The ELISA analytical biochemical technique of the MBS9309384 kit is based on TUBb3 antibody-TUBb3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TUBb3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TUBb3. Appropriate sample types may include undiluted human body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for TUBb3. It may not necessarily be applicable to this product.
 NCBI GI #    308235963
 NCBI GeneID    10381
 NCBI Accession #    NP_001184110.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001197181.1 [Other Products]
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 UniProt Primary Accession #    Q13509 [Other Products]
 UniProt Secondary Accession #    Q9BTZ0; Q9BW10 [Other Products]
 UniProt Related Accession #    Q13509 [Other Products]
 Molecular Weight    50,433 Da
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 NCBI Official Full Name    tubulin beta-3 chain isoform 2
 NCBI Official Synonym Full Names    tubulin, beta 3 class III
 NCBI Official Symbol    TUBB3 [Similar Products]
 NCBI Official Synonym Symbols   
CDCBM; FEOM3; TUBB4; CDCBM1; CFEOM3; beta-4; CFEOM3A
[Similar Products]
 NCBI Protein Information    tubulin beta-3 chain; tubulin beta-III; tubulin beta-4 chain; class III beta-tubulin; fibrosis of extraocular muscles, congenital, 3
 UniProt Protein Name    Tubulin beta-3 chain
 UniProt Synonym Protein Names   
Tubulin beta-4 chain; Tubulin beta-III
 Protein Family    Tubulin
 UniProt Gene Name    TUBB3 [Similar Products]
 UniProt Synonym Gene Names    TUBB4 [Similar Products]
 UniProt Entry Name    TBB3_HUMAN
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 NCBI Summary for TUBb3    This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Oct 2010]
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 UniProt Comments for TUBb3    TUBB3: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. TUBB3 plays a critical role in proper axon guidance and mantainance. Dimer of alpha and beta chains. Expression is primarily restricted to central and peripheral nervous system. Greatly increased expression in most cancerous tissues. Belongs to the tubulin family.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 16q24.3

Cellular Component: microtubule; cell soma; axon; cytoplasm; dendrite; nucleus

Molecular Function: GTPase activity; protein binding; GTP binding; structural constituent of cytoskeleton; peptide binding

Biological Process: protein polymerization; axon guidance; 'de novo' posttranslational protein folding; mitosis; cellular protein metabolic process; protein folding; transmembrane transport; microtubule-based process

Disease: Fibrosis Of Extraocular Muscles, Congenital, 3a, With Or Without Extraocular Involvement; Cortical Dysplasia, Complex, With Other Brain Malformations 1
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 Research Articles on TUBb3    1. Results indicate that Yg-3-46a has the potential to evade drug resistance mediated by P-gp and beta-III tubulin overexpression.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TUBb3 elisa kitPathways associated with TUBb3 elisa kit
 Reference Product  PubMed Publications
 POMC elisa kit  >2 publications with TUBb3 and POMC
 Products by Pathway  Pathway Diagram
 Chaperonin-mediated Protein Folding Pathway antibodies  Chaperonin-mediated Protein Folding Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway antibodies  Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway Diagram
 Diurnally Regulated Genes With Circadian Orthologs Pathway antibodies  Diurnally Regulated Genes With Circadian Orthologs Pathway Diagram
 Formation Of Tubulin Folding Intermediates By CCT/TriC Pathway antibodies  Formation Of Tubulin Folding Intermediates By CCT/TriC Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Gap Junction Pathway antibodies  Gap Junction Pathway Diagram
 Gap Junction Pathway antibodies  Gap Junction Pathway Diagram
Diseases associated with TUBb3 elisa kitOrgans/Tissues associated with TUBb3 elisa kit
 Disease Name  Pubmed Publications
 Fibrosis Of Extraocular Muscles, Congenital, 3A, with or without Extraocular Involvement Antibodies  >541 publications with TUBb3 and Fibrosis Of Extraocular Muscles, Congenital, 3A, with or without Extraocular Involvement
 Neoplasms Antibodies  >61 publications with TUBb3 and Neoplasms
 Nervous System Diseases Antibodies  >17 publications with TUBb3 and Nervous System Diseases
 Ovarian Neoplasms Antibodies  >14 publications with TUBb3 and Ovarian Neoplasms
 Breast Neoplasms Antibodies  >13 publications with TUBb3 and Breast Neoplasms
 Fibrosis Antibodies  >10 publications with TUBb3 and Fibrosis
 Neoplasms, Experimental Antibodies  >6 publications with TUBb3 and Neoplasms, Experimental
 Brain Diseases Antibodies  >5 publications with TUBb3 and Brain Diseases
 Eye Diseases Antibodies  >4 publications with TUBb3 and Eye Diseases
 Atrophy Antibodies  >3 publications with TUBb3 and Atrophy
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >29 publications with TUBb3 and Lung
 Brain Antibodies  >25 publications with TUBb3 and Brain
 Nerve Antibodies  >18 publications with TUBb3 and Nerve
 Muscle Antibodies  >12 publications with TUBb3 and Muscle
 Eye Antibodies  >10 publications with TUBb3 and Eye
 Heart Antibodies  >8 publications with TUBb3 and Heart
 Embryonic Tissue Antibodies  >7 publications with TUBb3 and Embryonic Tissue
 Blood Antibodies  >7 publications with TUBb3 and Blood
 Testis Antibodies  >4 publications with TUBb3 and Testis
 Bone Antibodies  >4 publications with TUBb3 and Bone
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