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Tyk-2 elisa kit :: Human Tyrosine Kinase 2 (Tyk-2) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS262546 Tyk-2 elisa kit
Unit / Price
48-Strip-Wells  /  $275 +1 FREE 8GB USB
96-Strip-Wells  /  $420 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,615 +2 FREE 8GB USB
10x96-Strip-Wells  /  $2,880 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Tyrosine Kinase 2 (Tyk-2), ELISA Kit

 Also Known As   

Human Tyrosine Kinase 2 (Tyk-2) ELISA Kit

 Product Gene Name   

Tyk-2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    gene 611521
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of Tyk-2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for Tyk-2 purchase    MBS262546 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Tyrosine Kinase 2 (Tyk-2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Tyk-2. The ELISA analytical biochemical technique of the MBS262546 kit is based on Tyk-2 antibody-Tyk-2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Tyk-2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Tyk-2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for Tyk-2. It may not necessarily be applicable to this product.
 NCBI GI #    15559784
 NCBI GeneID    7297
 NCBI Accession #    AAH14243.1 [Other Products]
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 UniProt Secondary Accession #    Q6QB10; Q96CH0 [Other Products]
 UniProt Related Accession #    P29597 [Other Products]
 Molecular Weight    133,650 Da
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 NCBI Official Full Name    Tyrosine kinase 2
 NCBI Official Synonym Full Names    tyrosine kinase 2
 NCBI Official Symbol    TYK2 [Similar Products]
 NCBI Official Synonym Symbols   
JTK1; IMD35
[Similar Products]
 NCBI Protein Information    non-receptor tyrosine-protein kinase TYK2
 UniProt Protein Name    Non-receptor tyrosine-protein kinase TYK2
 UniProt Gene Name    TYK2 [Similar Products]
 UniProt Entry Name    TYK2_HUMAN
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 NCBI Summary for Tyk-2    This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008]
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 UniProt Comments for Tyk-2    Tyk2: a non-receptor tyrosine-protein kinase of the JakA family. Activated in signaling from the IL-2, gp130 and IFN families of receptors. Phosphorylates the interferon-alpha/beta receptor alpha chain.

Protein type: Kinase, protein; EC 2.7.10.2; Protein kinase, TK; Protein kinase, tyrosine (non-receptor); TK group; JakA family

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: extrinsic to internal side of plasma membrane; cytoskeleton; cytoplasm; cytosol; nucleus

Molecular Function: protein binding; growth hormone receptor binding; protein-tyrosine kinase activity; non-membrane spanning protein tyrosine kinase activity; type 1 angiotensin receptor binding; ATP binding

Biological Process: cell migration; cytokine and chemokine mediated signaling pathway; innate immune response; cell differentiation; protein amino acid phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway; regulation of cell proliferation

Disease: Immunodeficiency 35
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 Research Articles on Tyk-2    1. Here, we report the 2.8-A structure of the two-domain pseudokinase-kinase module from the JAK family member TYK2 in its autoinhibited form.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Tyk-2 elisa kitPathways associated with Tyk-2 elisa kit
 Reference Product  PubMed Publications
 JAK1 elisa kit  >354 publications with Tyk-2 and JAK1
 STAT1 elisa kit  >229 publications with Tyk-2 and STAT1
 STAT3 elisa kit  >227 publications with Tyk-2 and STAT3
 STAT2 elisa kit  >117 publications with Tyk-2 and STAT2
 IFNAR1 elisa kit  >50 publications with Tyk-2 and IFNAR1
 SOCS1 elisa kit  >23 publications with Tyk-2 and SOCS1
 IFNAR2 elisa kit  >21 publications with Tyk-2 and IFNAR2
 IL6ST elisa kit  >18 publications with Tyk-2 and IL6ST
 PTPN6 elisa kit  >16 publications with Tyk-2 and PTPN6
 PTPN1 elisa kit  >5 publications with Tyk-2 and PTPN1
 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Hepatitis C Pathway antibodies  Hepatitis C Pathway Diagram
 Hepatitis C Pathway antibodies  Hepatitis C Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 IL-3 Signaling Pathway antibodies  IL-3 Signaling Pathway Diagram
 IL-4 Signaling Pathway antibodies  IL-4 Signaling Pathway Diagram
 IL-6 Signaling Pathway antibodies  IL-6 Signaling Pathway Diagram
Diseases associated with Tyk-2 elisa kitOrgans/Tissues associated with Tyk-2 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >54 publications with Tyk-2 and Inflammation
 Tyrosine Kinase 2 Deficiency Antibodies  >52 publications with Tyk-2 and Tyrosine Kinase 2 Deficiency
 Cardiovascular Diseases Antibodies  >25 publications with Tyk-2 and Cardiovascular Diseases
 Necrosis Antibodies  >20 publications with Tyk-2 and Necrosis
 Multiple Sclerosis Antibodies  >20 publications with Tyk-2 and Multiple Sclerosis
 Vascular Diseases Antibodies  >19 publications with Tyk-2 and Vascular Diseases
 Arthritis, Rheumatoid Antibodies  >17 publications with Tyk-2 and Arthritis, Rheumatoid
 Psoriasis Antibodies  >15 publications with Tyk-2 and Psoriasis
 Adenocarcinoma Antibodies  >14 publications with Tyk-2 and Adenocarcinoma
 Brain Diseases Antibodies  >14 publications with Tyk-2 and Brain Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >192 publications with Tyk-2 and Blood
 Liver Antibodies  >37 publications with Tyk-2 and Liver
 Skin Antibodies  >33 publications with Tyk-2 and Skin
 Bone Antibodies  >30 publications with Tyk-2 and Bone
 Muscle Antibodies  >30 publications with Tyk-2 and Muscle
 Vascular Antibodies  >27 publications with Tyk-2 and Vascular
 Bone Marrow Antibodies  >26 publications with Tyk-2 and Bone Marrow
 Lung Antibodies  >22 publications with Tyk-2 and Lung
 Brain Antibodies  >20 publications with Tyk-2 and Brain
 Kidney Antibodies  >17 publications with Tyk-2 and Kidney
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