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GALNT11 elisa kit :: Human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS924055
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11) (GALNT11), ELISA Kit

 Also Known As   

Human Polypeptide N-acetylgalactosaminyltransferase 11, GALNT11 ELISA Kit

 Product Synonym Names    Human Polypeptide N-acetylgalactosaminyltransferase 11 (GALNT11) ELISA kit; tcag7.1057; FLJ21634; MGC71630; GALNAC-T11; OTTHUMP00000211837; OTTHUMP00000211839; polypeptide N-acetylgalactosaminyltransferase 11; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
 Product Gene Name   

GALNT11 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS924055 Testing Data    Testing Data PDF
 OMIM    615130
 3D Structure    ModBase 3D Structure for Q8NCW6
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human GALNT11. No significant cross-reactivity or interference between Human GALNT11 and analogues was observed.
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 Assay Type    Sandwich
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of GALNT11 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for GALNT11 purchase    MBS924055 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11) (GALNT11) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GALNT11. The ELISA analytical biochemical technique of the MBS924055 kit is based on GALNT11 antibody-GALNT11 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GALNT11 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GALNT11. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for GALNT11 elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for GALNT11 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any GALNT11 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for GALNT11 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of GALNT11 bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of GALNT11 elisa kit    GALNT11 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS924055. Click to request current manual
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NCBI/Uniprot data below describe general gene information for GALNT11. It may not necessarily be applicable to this product.
 NCBI GI #    153792095
 NCBI GeneID    63917
 NCBI Accession #    NP_071370.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_022087.2 [Other Products]
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 UniProt Primary Accession #    Q8NCW6 [Other Products]
 UniProt Secondary Accession #    Q6PCD1; Q9H6C2; Q9H6Z5; Q9UDR8; B3KWF4 [Other Products]
 UniProt Related Accession #    Q8NCW6 [Other Products]
 Molecular Weight    68,919 Da
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 NCBI Official Full Name    polypeptide N-acetylgalactosaminyltransferase 11
 NCBI Official Synonym Full Names    polypeptide N-acetylgalactosaminyltransferase 11
 NCBI Official Symbol    GALNT11 [Similar Products]
 NCBI Official Synonym Symbols   
GALNACT11
[Similar Products]
 NCBI Protein Information    polypeptide N-acetylgalactosaminyltransferase 11; GALNAC-T11; pp-GaNTase 11; polypeptide GalNAc transferase 11; protein-UDP acetylgalactosaminyltransferase 11; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
 UniProt Protein Name    Polypeptide N-acetylgalactosaminyltransferase 11
 UniProt Synonym Protein Names   
Polypeptide GalNAc transferase 11; GalNAc-T11; pp-GaNTase 11; Protein-UDP acetylgalactosaminyltransferase 11; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11
 Protein Family    Polypeptide N-acetylgalactosaminyltransferase
 UniProt Gene Name    GALNT11 [Similar Products]
 UniProt Synonym Gene Names    GalNAc-T11; pp-GaNTase 11 [Similar Products]
 UniProt Entry Name    GLT11_HUMAN
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 UniProt Comments for GALNT11    GALNT11: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Displays the same enzyme activity toward Muc1, Muc4.1, and EA2 than GALNT1. Does not appear to be involved in glycosylation of erythropoietin. Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Glycan Metabolism - O-glycan biosynthesis; EC 2.4.1.41; Transferase; Membrane protein, integral

Chromosomal Location of Human Ortholog: 7q36.1|7q36.1

Cellular Component: Golgi membrane; integral to membrane

Molecular Function: metal ion binding; polypeptide N-acetylgalactosaminyltransferase activity; carbohydrate binding; Notch binding

Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; regulation of Notch signaling pathway; O-glycan processing; Notch receptor processing; protein amino acid O-linked glycosylation via threonine; determination of left/right symmetry; post-translational protein modification
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 Research Articles on GALNT11    1. evidence suggests that CLL patient samples harbor aberrant O-glycosylation highlighted by Tn antigen expression and that the over-expression of GALNT11 constitutes a new molecular marker for CLL
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with GALNT11 elisa kitDiseases associated with GALNT11 elisa kit
 Products by Pathway  Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Mucin Type O-Glycan Biosynthesis Pathway antibodies  Mucin Type O-Glycan Biosynthesis Pathway Diagram
 Mucin Type O-Glycan Biosynthesis Pathway antibodies  Mucin Type O-Glycan Biosynthesis Pathway Diagram
 O-glycan Biosynthesis, Mucin Type Core Pathway antibodies  O-glycan Biosynthesis, Mucin Type Core Pathway Diagram
 O-glycan Biosynthesis, Mucin Type Core Pathway antibodies  O-glycan Biosynthesis, Mucin Type Core Pathway Diagram
 O-linked Glycosylation Of Mucins Pathway antibodies  O-linked Glycosylation Of Mucins Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
 Disease Name  Pubmed Publications
 Heart Defects, Congenital Antibodies  >1 publications with GALNT11 and Heart Defects, Congenital
Organs/Tissues associated with GALNT11 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >1 publications with GALNT11 and Heart
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