NP_001001521.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
56,940 Da
NCBI Official Full Name
UTP--glucose-1-phosphate uridylyltransferase isoform b
NCBI Official Synonym Full Names
UDP-glucose pyrophosphorylase 2
NCBI Official Synonym Symbols
UDPG; UGP1; UDPGP; UGPP1; UGPP2; UDPGP2; pHC379 [Similar Products]
NCBI Protein Information
UTP--glucose-1-phosphate uridylyltransferase; UGPase 2; UDP-glucose diphosphorylase; UDP-glucose pyrophosphorylase 1; UTP-glucose-1-phosphate uridyltransferase; UTP--glucose-1-phosphate uridylyltransferase 2; Uridyl diphosphate glucose pyrophosphorylase-1; uridyl diphosphate glucose pyrophosphorylase 2
UniProt Protein Name
UTP--glucose-1-phosphate uridylyltransferase
UniProt Synonym Protein Names
UDP-glucose pyrophosphorylase; UDPGP; UGPase
UniProt Synonym Gene Names
UniProt Entry Name
UGPA_HUMAN
NCBI Summary for UGP2
The enzyme encoded by this gene is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for UGP2
UGP2: Plays a central role as a glucosyl donor in cellular metabolic pathways. Belongs to the UDPGP type 1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Carbohydrate Metabolism - amino sugar and nucleotide sugar; Carbohydrate Metabolism - starch and sucrose; Carbohydrate Metabolism - galactose; Carbohydrate Metabolism - pentose and glucuronate interconversions; Transferase; EC 2.7.7.9
Chromosomal Location of Human Ortholog: 2p14-p13
Cellular Component: cytosol; nucleus
Molecular Function: pyrimidine ribonucleotide binding; protein binding; UTP:glucose-1-phosphate uridylyltransferase activity; metal ion binding; glucose binding
Biological Process: glycogen biosynthetic process; xenobiotic metabolic process; carbohydrate metabolic process; glucose metabolic process; pathogenesis; glucose 1-phosphate metabolic process; UDP-glucuronate biosynthetic process; UDP-glucose metabolic process
Research Articles on UGP2
Precautions
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Pathways associated with UGP2 elisa kit
Products by Pathway |
Pathway Diagram |
Amino Sugar And Nucleotide Sugar Metabolism Pathway antibodies |
Amino Sugar And Nucleotide Sugar Metabolism Pathway Diagram |
Amino Sugar And Nucleotide Sugar Metabolism Pathway antibodies |
Amino Sugar And Nucleotide Sugar Metabolism Pathway Diagram |
Ascorbate Biosynthesis, Animals, Glucose-1P => Ascorbate Pathway antibodies |
Ascorbate Biosynthesis, Animals, Glucose-1P => Ascorbate Pathway Diagram |
Ascorbate Biosynthesis, Animals, Glucose-1P => Ascorbate Pathway antibodies |
Ascorbate Biosynthesis, Animals, Glucose-1P => Ascorbate Pathway Diagram |
Biological Oxidations Pathway antibodies |
Biological Oxidations Pathway Diagram |
Diurnally Regulated Genes With Circadian Orthologs Pathway antibodies |
Diurnally Regulated Genes With Circadian Orthologs Pathway Diagram |
Formation Of The Active Cofactor, UDP-glucuronate Pathway antibodies |
Formation Of The Active Cofactor, UDP-glucuronate Pathway Diagram |
Galactose Metabolism Pathway antibodies |
Galactose Metabolism Pathway Diagram |
Galactose Metabolism Pathway antibodies |
Galactose Metabolism Pathway Diagram |
Glucose Metabolism Pathway antibodies |
Glucose Metabolism Pathway Diagram |
Diseases associated with UGP2 elisa kit
Organs/Tissues associated with UGP2 elisa kit
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