NP_659489.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
19,056 Da
NCBI Official Full Name
uracil phosphoribosyltransferase homolog
NCBI Official Synonym Full Names
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
NCBI Official Synonym Symbols
NCBI Protein Information
uracil phosphoribosyltransferase homolog; UPRTase; RP11-311P8.3; UMP pyrophosphorylase
UniProt Protein Name
Uracil phosphoribosyltransferase homolog
UniProt Entry Name
UPP_HUMAN
NCBI Summary for UPRT
This gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer. [provided by RefSeq, Nov 2009]
UniProt Comments for UPRT
UPRT: an enzyme which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer. [provided by RefSeq, Nov 2009]
Protein type: Nucleotide Metabolism - pyrimidine; EC 2.4.2.9; Transferase
Chromosomal Location of Human Ortholog: Xq13.3
Cellular Component: cytoplasm; nucleus
Biological Process: lactation; UMP biosynthetic process; female pregnancy; response to insulin stimulus
Research Articles on UPRT
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Pathways associated with UPRT elisa kit
Diseases associated with UPRT elisa kit
Organs/Tissues associated with UPRT elisa kit
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