AAL99574.1
[Other Products]
Molecular Weight
47,527 Da
NCBI Official Full Name
visceral adipose tissue specific SERPIN
UniProt Protein Name
Serpin A12
UniProt Synonym Protein Names
Visceral adipose tissue-derived serine protease inhibitor; Vaspin; Visceral adipose-specific serpin
UniProt Synonym Gene Names
UniProt Entry Name
SPA12_RAT
UniProt Comments for VASPIN
SERPINA12: May modulate insulin action conceivably only in the presence of its yet undefined target proteases in white adipose tissues. Belongs to the serpin family.
Protein type: Inhibitor; Secreted; Secreted, signal peptide
Cellular Component: extracellular space; plasma membrane
Molecular Function: serine-type endopeptidase inhibitor activity
Biological Process: positive regulation of phosphoinositide 3-kinase cascade; negative regulation of lipid biosynthetic process; negative regulation of gluconeogenesis; glucose metabolic process; positive regulation of insulin receptor signaling pathway
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