NP_663627.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
13,313 Da
NCBI Official Full Name
WAP four-disulfide core domain protein 5
NCBI Official Synonym Full Names
WAP four-disulfide core domain 5
NCBI Protein Information
WAP four-disulfide core domain protein 5
UniProt Protein Name
WAP four-disulfide core domain protein 5
UniProt Synonym Protein Names
Putative protease inhibitor WAP1; p53-responsive gene 5 protein
UniProt Synonym Gene Names
UniProt Entry Name
WFDC5_HUMAN
NCBI Summary for WFDC5
This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. Most WFDC proteins contain only one WFDC domain, and this encoded protein contains two WFDC domains. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. [provided by RefSeq, Jul 2008]
UniProt Comments for WFDC5
WFDC5: Putative acid-stable proteinase inhibitor. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 20q13.12
Cellular Component: extracellular region
Molecular Function: serine-type endopeptidase inhibitor activity
Research Articles on WFDC5
Precautions
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Organs/Tissues associated with WFDC5 elisa kit
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