Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow ELISA Kit rightarrow XRCC5 rightarrow Human XRCC5  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • A Disintegrin and Metalloproteinase With Thrombospondin 5 (A... ELISA Kit
 • Alternative Macrophage Activation-Associated Cc Chemokine 1 ... ELISA Kit
 • Tricarboxylate transport (SLC20A3) Recombinant Protein
 • Gamma-Synuclein (SNCG) Antibody
 • Monocyte-Granulocyte Antibody
 • Hemoglobin (RB1909) Antibody
 • FK ELISA Kit
 • fucosyltransferase 6 (alpha (1, 3) fucosyltransferase) (FUT... ELISA Kit
 • SCY1-like 1 (S. cerevisiae) (SCYL1) ELISA Kit
 • GNAS Antibody
 • A-RAF (ARAF) Antibody
 • Cat IgG (Fab'2) Immunoglobulin
 • chromosome 8 open reading frame 47 (C8orf47) ELISA Kit
 • ABCE1-RNase L Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

XRCC5 elisa kit :: Human X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9340932 XRCC5 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) (XRCC5), ELISA Kit

 Also Known As   

Human X-ray repair cross-complementing protein 5, XRCC5 ELISA Kit

 Product Synonym Names    Human X-ray repair cross-complementing protein 5 (XRCC5) ELISA kit; FLJ39089; KARP-1; KARP1; KU80; KUB2; Ku86; NFIV; ATP-dependent DNA helicase II; DNA repair protein XRCC5; Ku autoantigen; 80kDa; Ku86 autoantigen related protein 1; OTTHUMP00000164061; OTTHUMP00000206791; X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
 Product Gene Name   

XRCC5 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Request for Manual Insert    Request Manual
 OMIM    194364
 3D Structure    ModBase 3D Structure for P13010
Section Bar
 Species Reactivity    Human
Section Bar
Section Bar
 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of XRCC5 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for XRCC5 purchase    MBS9340932 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) (XRCC5) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing XRCC5. The ELISA analytical biochemical technique of the MBS9340932 kit is based on XRCC5 antibody-XRCC5 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect XRCC5 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, XRCC5. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for XRCC5. It may not necessarily be applicable to this product.
 NCBI GI #    10863945
 NCBI GeneID    7520
 NCBI Accession #    NP_066964.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_021141.3 [Other Products]
Section Bar
 UniProt Primary Accession #    P13010 [Other Products]
 UniProt Secondary Accession #    Q0Z7V0; Q4VBQ5; Q53HH7; Q7M4N0; Q9UCQ0; Q9UCQ1; A8K3X5 [Other Products]
 UniProt Related Accession #    P13010 [Other Products]
 Molecular Weight    82,705 Da
Table BarTOPTable Bar
 NCBI Official Full Name    X-ray repair cross-complementing protein 5
 NCBI Official Synonym Full Names    X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
 NCBI Official Symbol    XRCC5 [Similar Products]
 NCBI Official Synonym Symbols   
KU80; KUB2; Ku86; NFIV; KARP1; KARP-1
[Similar Products]
 NCBI Protein Information    X-ray repair cross-complementing protein 5; TLAA; CTC85; CTCBF; nuclear factor IV; Ku autoantigen, 80kDa; DNA repair protein XRCC5; thyroid-lupus autoantigen; 86 kDa subunit of Ku antigen; lupus Ku autoantigen protein p86; Ku86 autoantigen related protein 1; CTC box-binding factor 85 kDa subunit; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit
 UniProt Protein Name    X-ray repair cross-complementing protein 5
 UniProt Synonym Protein Names   
86 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box-binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair protein XRCC5; Ku80; Ku86; Lupus Ku autoantigen protein p86; Nuclear factor IV; Thyroid-lupus autoantigen; TLAA; X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
 UniProt Gene Name    XRCC5 [Similar Products]
 UniProt Synonym Gene Names    G22P2; CTC85; CTCBF; TLAA [Similar Products]
 UniProt Entry Name    XRCC5_HUMAN
Section Bar
 NCBI Summary for XRCC5    The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for XRCC5    Ku80: the 80-kilodalton subunit of the Ku complex, also known as ATP-dependant DNA helicase II. A single stranded DNA-dependent ATP-dependent helicase. It functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to DNA may be mediated by p70.

Protein type: Helicase; Nucleolus; EC 3.6.1.-; EC 3.6.4.-; RNA-binding; Nuclear receptor co-regulator; DNA-binding

Chromosomal Location of Human Ortholog: 2q35

Cellular Component: nucleoplasm; nuclear telomere cap complex; nuclear chromosome, telomeric region; membrane; nucleolus; plasma membrane; nucleus; cytosol

Molecular Function: protein C-terminus binding; ATP-dependent DNA helicase activity; protein binding; DNA binding; ubiquitin protein ligase binding; double-stranded DNA binding; telomeric DNA binding; damaged DNA binding; double-stranded telomeric DNA binding; 5'-deoxyribose-5-phosphate lyase activity; ATP binding

Biological Process: response to drug; positive regulation of neurogenesis; transcription, DNA-dependent; viral reproduction; DNA repair; double-strand break repair via nonhomologous end joining; DNA duplex unwinding; DNA recombination; cell proliferation; double-strand break repair; positive regulation of interferon type I production; innate immune response; brain development; negative regulation of transcription, DNA-dependent; telomere maintenance
Table BarTOPTable Bar
 Research Articles on XRCC5    1. down-regulation of Ku80 can sensitize ALT cells U2OS to radiation, and this radiosensitization is related to telomere length shortening.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with XRCC5 elisa kitPathways associated with XRCC5 elisa kit
 Reference Product  PubMed Publications
 PRKDC elisa kit  >206 publications with XRCC5 and PRKDC
 ATM elisa kit  >26 publications with XRCC5 and ATM
 WRN elisa kit  >18 publications with XRCC5 and WRN
 PCNA elisa kit  >12 publications with XRCC5 and PCNA
 XRCC6 elisa kit  >11 publications with XRCC5 and XRCC6
 MYC elisa kit  >8 publications with XRCC5 and MYC
 HSF1 elisa kit  >7 publications with XRCC5 and HSF1
 CD40 elisa kit  >7 publications with XRCC5 and CD40
 NBN elisa kit  >4 publications with XRCC5 and NBN
 ATR elisa kit  >4 publications with XRCC5 and ATR
 Products by Pathway  Pathway Diagram
 2-LTR Circle Formation Pathway antibodies  2-LTR Circle Formation Pathway Diagram
 BARD1 Signaling Events Pathway antibodies  BARD1 Signaling Events Pathway Diagram
 Coregulation Of Androgen Receptor Activity Pathway antibodies  Coregulation Of Androgen Receptor Activity Pathway Diagram
 DNA Repair Pathway antibodies  DNA Repair Pathway Diagram
 DNA-PK Complex Pathway antibodies  DNA-PK Complex Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Double-Strand Break Repair Pathway antibodies  Double-Strand Break Repair Pathway Diagram
 Early Phase Of HIV Life Cycle Pathway antibodies  Early Phase Of HIV Life Cycle Pathway Diagram
 HIV Infection Pathway antibodies  HIV Infection Pathway Diagram
 HIV Life Cycle Pathway antibodies  HIV Life Cycle Pathway Diagram
Diseases associated with XRCC5 elisa kitOrgans/Tissues associated with XRCC5 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >132 publications with XRCC5 and Neoplasms
 Chromosome Aberrations Antibodies  >51 publications with XRCC5 and Chromosome Aberrations
 Carcinoma Antibodies  >40 publications with XRCC5 and Carcinoma
 Nervous System Diseases Antibodies  >39 publications with XRCC5 and Nervous System Diseases
 Skin Diseases Antibodies  >29 publications with XRCC5 and Skin Diseases
 Ataxia Antibodies  >28 publications with XRCC5 and Ataxia
 Cardiovascular Diseases Antibodies  >27 publications with XRCC5 and Cardiovascular Diseases
 Brain Diseases Antibodies  >21 publications with XRCC5 and Brain Diseases
 Lung Diseases Antibodies  >16 publications with XRCC5 and Lung Diseases
 Neoplasms, Experimental Antibodies  >14 publications with XRCC5 and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >88 publications with XRCC5 and Blood
 Brain Antibodies  >28 publications with XRCC5 and Brain
 Ovary Antibodies  >24 publications with XRCC5 and Ovary
 Lung Antibodies  >21 publications with XRCC5 and Lung
 Liver Antibodies  >20 publications with XRCC5 and Liver
 Skin Antibodies  >10 publications with XRCC5 and Skin
 Bone Antibodies  >10 publications with XRCC5 and Bone
 Testis Antibodies  >9 publications with XRCC5 and Testis
 Bone Marrow Antibodies  >8 publications with XRCC5 and Bone Marrow
 Embryonic Tissue Antibodies  >8 publications with XRCC5 and Embryonic Tissue
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions