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ASCC3 elisa kit :: Human activating signal cointegrator 1 complex subunit 3 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9338823 ASCC3 elisa kit
Unit / Price
48-Strip-Wells  /  $500 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,250 +4 FREE 8GB USB
10x96-Strip-Wells  /  $6,395 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

activating signal cointegrator 1 complex subunit 3 (ASCC3), ELISA Kit

 Also Known As   

Human Activating signal cointegrator 1 complex subunit 3, ASCC3 ELISA Kit

 Product Synonym Names    Human Activating signal cointegrator 1 complex subunit 3 (ASCC3) ELISA kit; ASC1p200; DJ467N11.1; HELIC1; MGC26074; RNAH; dJ121G13.4; ASC-1 complex subunit P200; B630009I04Rik; OTTHUMP00000016905; RNA helicase family; helicase; ATP binding 1; activating signal cointegrator 1 complex subunit 3
 Product Gene Name   

ASCC3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    614217
 3D Structure    ModBase 3D Structure for Q8N3C0
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ASCC3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ASCC3 purchase    MBS9338823 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the activating signal cointegrator 1 complex subunit 3 (ASCC3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ASCC3. The ELISA analytical biochemical technique of the MBS9338823 kit is based on ASCC3 antibody-ASCC3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ASCC3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ASCC3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for ASCC3. It may not necessarily be applicable to this product.
 NCBI GI #    546232111
 NCBI GeneID    10973
 NCBI Accession #    NP_001271200.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001284271.1 [Other Products]
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 UniProt Primary Accession #    Q8N3C0 [Other Products]
 UniProt Secondary Accession #    O43738; Q4G1A0; Q5VTN2; Q9H1I9; Q9H5A2; Q9NTR0; E7EW23 [Other Products]
 UniProt Related Accession #    Q8N3C0 [Other Products]
 Molecular Weight    251,460 Da
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 NCBI Official Full Name    activating signal cointegrator 1 complex subunit 3 isoform c
 NCBI Official Synonym Full Names    activating signal cointegrator 1 complex subunit 3
 NCBI Official Symbol    ASCC3 [Similar Products]
 NCBI Official Synonym Symbols   
RNAH; HELIC1; ASC1p200
[Similar Products]
 NCBI Protein Information    activating signal cointegrator 1 complex subunit 3; RNA helicase family; helicase, ATP binding 1; ASC-1 complex subunit P200; trip4 complex subunit p200
 UniProt Protein Name    Activating signal cointegrator 1 complex subunit 3
 UniProt Synonym Protein Names   
ASC-1 complex subunit p200; ASC1p200; Helicase, ATP binding 1; Trip4 complex subunit p200
 Protein Family    Activating signal cointegrator 1 complex
 UniProt Gene Name    ASCC3 [Similar Products]
 UniProt Synonym Gene Names    HELIC1; ASC1p200 [Similar Products]
 UniProt Entry Name    ASCC3_HUMAN
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 NCBI Summary for ASCC3    This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes. The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
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 UniProt Comments for ASCC3    ASCC3: 3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3, enabling ALKHB3 to process alkylated N3- methylcytosine (3mC) within double-stranded regions. Enhances NF- kappa-B, SRF and AP1 transactivation. Belongs to the helicase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription, coactivator/corepressor; Helicase; EC 3.6.4.12

Chromosomal Location of Human Ortholog: 6q16

Cellular Component: Golgi apparatus; membrane; cytoplasm; intracellular; nucleus

Molecular Function: protein binding; ATP-dependent 3'-5' DNA helicase activity; ATP binding

Biological Process: cell proliferation; DNA dealkylation; transcription, DNA-dependent; regulation of transcription, DNA-dependent; DNA duplex unwinding
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 Research Articles on ASCC3    1. Silencing of ASCC3 resulted in upregulation of multiple antiviral interferon-stimulated genes, which correlated with inhibition of infection of several positive-strand RNA viruses.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with ASCC3 elisa kit
 Disease Name  Pubmed Publications
 Prostatic Neoplasms Antibodies  >1 publications with ASCC3 and Prostatic Neoplasms
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