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AKR1C1 elisa kit :: Human aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha) -hydroxysteroid dehydrogenase) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9316485 AKR1C1 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha) -hydroxysteroid dehydrogenase) (AKR1C1), ELISA Kit

 Also Known As   

Human Aldo-keto reductase family 1 member C1, AKR1C1 ELISA Kit

 Product Synonym Names    Human Aldo-keto reductase family 1 member C1 (AKR1C1) ELISA kit; RP11-69D4.1; 2-ALPHA-HSD; 20-ALPHA-HSD; C9; DD1; DDH; DDH1; H-37; HAKRC; MBAB; MGC8954; 20 alpha-hydroxysteroid dehydrogenase; aldo-keto reductase C; aldo-keto reductase family 1; member C1; chlordecon; aldo-keto reductase family 1; member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha) -hydroxysteroid dehydrogenase)
 Product Gene Name   

AKR1C1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    600449
 3D Structure    ModBase 3D Structure for Q04828
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of AKR1C1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for AKR1C1 purchase    MBS9316485 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha) -hydroxysteroid dehydrogenase) (AKR1C1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing AKR1C1. The ELISA analytical biochemical technique of the MBS9316485 kit is based on AKR1C1 antibody-AKR1C1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect AKR1C1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, AKR1C1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for AKR1C1. It may not necessarily be applicable to this product.
 NCBI GI #    5453543
 NCBI GeneID    1645
 NCBI Accession #    NP_001344.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001353.5 [Other Products]
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 UniProt Primary Accession #    Q04828 [Other Products]
 UniProt Secondary Accession #    P52896; Q5SR15; Q7M4N2; Q9UCX2 [Other Products]
 UniProt Related Accession #    Q04828 [Other Products]
 Molecular Weight    36,788 Da
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 NCBI Official Full Name    aldo-keto reductase family 1 member C1
 NCBI Official Synonym Full Names    aldo-keto reductase family 1, member C1
 NCBI Official Symbol    AKR1C1 [Similar Products]
 NCBI Official Synonym Symbols   
C9; DD1; DDH; DDH1; H-37; HBAB; MBAB; HAKRC; DD1/DD2; 2-ALPHA-HSD; 20-ALPHA-HSD
[Similar Products]
 NCBI Protein Information    aldo-keto reductase family 1 member C1; aldo-keto reductase C; indanol dehydrogenase; dihydrodiol dehydrogenase 1; dihydrodiol dehydrogenase 1/2; hepatic dihydrodiol dehydrogenase; chlordecone reductase homolog HAKRC; 20 alpha-hydroxysteroid dehydrogenase; 20-alpha-hydroxysteroid dehydrogenase; dihydrodiol dehydrogenase isoform DD1; type II 3-alpha-hydroxysteroid dehydrogenase; high-affinity hepatic bile acid-binding protein; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase
 UniProt Protein Name    Aldo-keto reductase family 1 member C1
 UniProt Synonym Protein Names   
20-alpha-hydroxysteroid dehydrogenase (EC:1.1.1.149); 20-alpha-HSD; Chlordecone reductase homolog HAKRC; Dihydrodiol dehydrogenase 1/2; DD1/DD2; High-affinity hepatic bile acid-binding protein; HBAB; Indanol dehydrogenase (EC:1.1.1.112); Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC:1.3.1.20)
 Protein Family    Aldo-keto reductase family
 UniProt Gene Name    AKR1C1 [Similar Products]
 UniProt Synonym Gene Names    DDH; DDH1; 20-alpha-HSD; DD1/DD2; HBAB [Similar Products]
 UniProt Entry Name    AK1C1_HUMAN
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 NCBI Summary for AKR1C1    This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]
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 UniProt Comments for AKR1C1    AKR1C1: Converts progesterone to its inactive form, 20-alpha- dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation. Belongs to the aldo/keto reductase family.

Protein type: EC 1.1.1.112; Oxidoreductase; EC 1.3.1.20; Xenobiotic Metabolism - metabolism by cytochrome P450; EC 1.1.1.149

Chromosomal Location of Human Ortholog: 10p15-p14

Cellular Component: cytosol

Molecular Function: oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; ketosteroid monooxygenase activity; 3-alpha-hydroxysteroid dehydrogenase (B-specific) activity; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; bile acid binding; carboxylic acid binding; aldo-keto reductase activity; 20-alpha-hydroxysteroid dehydrogenase activity; indanol dehydrogenase activity; aldehyde reductase activity; phenanthrene 9,10-monooxygenase activity

Biological Process: bile acid and bile salt transport; phototransduction, visible light; cholesterol homeostasis; response to organophosphorus; retinal metabolic process; epithelial cell differentiation; bile acid metabolic process; xenobiotic metabolic process; digestion; cholesterol absorption; progesterone metabolic process; retinoid metabolic process; protein homooligomerization
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 Research Articles on AKR1C1    1. Studies indicate that mutations in aldo-keto reductase family 1 (AKR1) enzymes AKR1C1 and AKR1C4 are responsible for sexual development dysgenesis and mutations in AKR1D1 are causative in bile-acid deficiency.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with AKR1C1 elisa kitPathways associated with AKR1C1 elisa kit
 Reference Product  PubMed Publications
 CYP1A1 elisa kit  >11 publications with AKR1C1 and CYP1A1
 EPHX1 elisa kit  >2 publications with AKR1C1 and EPHX1
 CYP1A2 elisa kit  >2 publications with AKR1C1 and CYP1A2
 HSD17B3 elisa kit  >1 publications with AKR1C1 and HSD17B3
 CYP2B6 elisa kit  >1 publications with AKR1C1 and CYP2B6
 Products by Pathway  Pathway Diagram
 Benzo(a)pyrene Metabolism Pathway antibodies  Benzo(a)pyrene Metabolism Pathway Diagram
 Bile Acid And Bile Salt Metabolism Pathway antibodies  Bile Acid And Bile Salt Metabolism Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Diseases Associated With Visual Transduction Pathway antibodies  Diseases Associated With Visual Transduction Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Metabolism Of Xenobiotics By Cytochrome P450 Pathway antibodies  Metabolism Of Xenobiotics By Cytochrome P450 Pathway Diagram
 Metabolism Of Xenobiotics By Cytochrome P450 Pathway antibodies  Metabolism Of Xenobiotics By Cytochrome P450 Pathway Diagram
 Retinoid Metabolism And Transport Pathway antibodies  Retinoid Metabolism And Transport Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
Diseases associated with AKR1C1 elisa kitOrgans/Tissues associated with AKR1C1 elisa kit
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >21 publications with AKR1C1 and Carcinoma
 Breast Neoplasms Antibodies  >17 publications with AKR1C1 and Breast Neoplasms
 Adenocarcinoma Antibodies  >13 publications with AKR1C1 and Adenocarcinoma
 Lung Neoplasms Antibodies  >10 publications with AKR1C1 and Lung Neoplasms
 Endometriosis Antibodies  >10 publications with AKR1C1 and Endometriosis
 Liver Neoplasms Antibodies  >6 publications with AKR1C1 and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >5 publications with AKR1C1 and Carcinoma, Hepatocellular
 Carcinoma, Non-Small-Cell Lung Antibodies  >4 publications with AKR1C1 and Carcinoma, Non-Small-Cell Lung
 Inflammation Antibodies  >3 publications with AKR1C1 and Inflammation
 Endometrial Neoplasms Antibodies  >3 publications with AKR1C1 and Endometrial Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >23 publications with AKR1C1 and Liver
 Lung Antibodies  >20 publications with AKR1C1 and Lung
 Ovary Antibodies  >8 publications with AKR1C1 and Ovary
 Uterus Antibodies  >8 publications with AKR1C1 and Uterus
 Adipose Tissue Antibodies  >7 publications with AKR1C1 and Adipose Tissue
 Connective Tissue Antibodies  >7 publications with AKR1C1 and Connective Tissue
 Skin Antibodies  >7 publications with AKR1C1 and Skin
 Brain Antibodies  >6 publications with AKR1C1 and Brain
 Intestine Antibodies  >6 publications with AKR1C1 and Intestine
 Mammary Gland Antibodies  >6 publications with AKR1C1 and Mammary Gland
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