NP_001147.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
52,739 Da
NCBI Official Full Name
annexin A7 isoform 1
NCBI Official Synonym Full Names
annexin A7
NCBI Protein Information
annexin A7; annexin-7; annexin VII
UniProt Protein Name
Annexin A7
UniProt Synonym Protein Names
Annexin VII; Annexin-7; Synexin
UniProt Synonym Gene Names
UniProt Entry Name
ANXA7_HUMAN
NCBI Summary for ANXA7
Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion. [provided by RefSeq, Jul 2008]
UniProt Comments for ANXA7
Function: Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.
Research Articles on ANXA7
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Products associated with ANXA7 elisa kit
Diseases associated with ANXA7 elisa kit
Organs/Tissues associated with ANXA7 elisa kit
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