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AHR elisa kit :: Human aryl hydrocarbon receptor ELISA Kit

Scan QR to view Datasheet Catalog #    MBS702604
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $550 +1 FREE 8GB USB
96-Strip-Wells  /  $795 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,890 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,465 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

aryl hydrocarbon receptor (AHR), ELISA Kit

★Popular Item★
 Also Known As   

Human aryl hydrocarbon receptor, AhR ELISA Kit

 Product Synonym Names    Human aryl hydrocarbon receptor; AhR ELISA Kit; bHLHe76; AH-receptor; aromatic hydrocarbon receptor; aryl hydrocarbon receptor
 Product Gene Name   

AHR elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS702604 Testing Data    Testing Data PDF
 OMIM    600253
 3D Structure    ModBase 3D Structure for P35869
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of human AhR. No significant cross-reactivity or interference between human AhR and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates, cell lysates
 Detection Range    15.6 pg/ml -1000 pg/mL
 Sensitivity    <3.9 pg/mL
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of AHR elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for AHR purchase    MBS702604 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the aryl hydrocarbon receptor (AHR) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 15.6 pg/ml -1000 pg/mL in biological research samples containing AHR, with an estimated sensitivity of <3.9 pg/mL. The ELISA analytical biochemical technique of the MBS702604 kit is based on AHR antibody-AHR antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect AHR antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, AHR. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates, cell lysates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for AHR elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for AhR has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any AhR present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for AhR is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of AhR bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of AHR elisa kit    AHR elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS702604. Click to request current manual
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NCBI/Uniprot data below describe general gene information for AHR. It may not necessarily be applicable to this product.
 NCBI GI #    4502003
 NCBI GeneID    196
 NCBI Accession #    NP_001612.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001621.4 [Other Products]
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 UniProt Primary Accession #    P35869 [Other Products]
 UniProt Secondary Accession #    Q13728; Q13803; Q13804; A4D130 [Other Products]
 UniProt Related Accession #    P35869 [Other Products]
 Molecular Weight    96,147 Da
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 NCBI Official Full Name    aryl hydrocarbon receptor
 NCBI Official Synonym Full Names    aryl hydrocarbon receptor
 NCBI Official Symbol    AHR [Similar Products]
 NCBI Official Synonym Symbols   
bHLHe76
[Similar Products]
 NCBI Protein Information    aryl hydrocarbon receptor; AH-receptor; ah receptor; aromatic hydrocarbon receptor; class E basic helix-loop-helix protein 76
 UniProt Protein Name    Aryl hydrocarbon receptor
 UniProt Synonym Protein Names   
Class E basic helix-loop-helix protein 76; bHLHe76
 Protein Family    Aldehyde reductase
 UniProt Gene Name    AHR [Similar Products]
 UniProt Synonym Gene Names    BHLHE76; Ah receptor; AhR; bHLHe76 [Similar Products]
 UniProt Entry Name    AHR_HUMAN
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 NCBI Summary for AHR    This gene encodes a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Its ligands included a variety of aromatic hydrocarbons. [provided by RefSeq, Jul 2008]
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 UniProt Comments for AHR    Function: Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.2 PublicationsManual assertion based on experiment in:Ref.10
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 Research Articles on AHR    1. The AhR ligand, TCDD, induces hepatic fibrosis by directly regulating profibrotic pathways.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with AHR elisa kitPathways associated with AHR elisa kit
 Reference Product  PubMed Publications
 CYP1A1 elisa kit  >1348 publications with AHR and CYP1A1
 ARNT elisa kit  >632 publications with AHR and ARNT
 CYP1B1 elisa kit  >370 publications with AHR and CYP1B1
 SRC elisa kit  >45 publications with AHR and SRC
 AIP elisa kit  >27 publications with AHR and AIP
 RELA elisa kit  >18 publications with AHR and RELA
 ESR1 elisa kit  >12 publications with AHR and ESR1
 RB1 elisa kit  >6 publications with AHR and RB1
 HSP90AA1 elisa kit  >3 publications with AHR and HSP90AA1
 SMARCA4 elisa kit  >2 publications with AHR and SMARCA4
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 AhR Pathway antibodies  AhR Pathway Diagram
 Integrated Breast Cancer Pathway antibodies  Integrated Breast Cancer Pathway Diagram
Diseases associated with AHR elisa kitOrgans/Tissues associated with AHR elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1291 publications with AHR and Inflammation
 Liver Diseases Antibodies  >335 publications with AHR and Liver Diseases
 Breast Neoplasms Antibodies  >253 publications with AHR and Breast Neoplasms
 Liver Neoplasms Antibodies  >251 publications with AHR and Liver Neoplasms
 Necrosis Antibodies  >203 publications with AHR and Necrosis
 Carcinoma, Hepatocellular Antibodies  >149 publications with AHR and Carcinoma, Hepatocellular
 Pneumonia Antibodies  >149 publications with AHR and Pneumonia
 Hyperplasia Antibodies  >145 publications with AHR and Hyperplasia
 Neoplasms, Experimental Antibodies  >141 publications with AHR and Neoplasms, Experimental
 Kidney Diseases Antibodies  >115 publications with AHR and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1215 publications with AHR and Blood
 Lung Antibodies  >1077 publications with AHR and Lung
 Liver Antibodies  >871 publications with AHR and Liver
 Muscle Antibodies  >295 publications with AHR and Muscle
 Skin Antibodies  >215 publications with AHR and Skin
 Brain Antibodies  >203 publications with AHR and Brain
 Bone Antibodies  >155 publications with AHR and Bone
 Spleen Antibodies  >122 publications with AHR and Spleen
 Intestine Antibodies  >102 publications with AHR and Intestine
 Bone Marrow Antibodies  >101 publications with AHR and Bone Marrow
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