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ATOH7 elisa kit :: Human atonal homolog 7 (Drosophila) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9320366 ATOH7 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

atonal homolog 7 (Drosophila) (ATOH7), ELISA Kit

 Also Known As   

Human Protein atonal homolog 7, ATOH7 ELISA Kit

 Product Synonym Names    Human Protein atonal homolog 7 (ATOH7) ELISA kit; Math5; bHLHa13; atonal homolog 7; atonal homolog 7 (Drosophila)
 Product Gene Name   

ATOH7 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    609875
 3D Structure    ModBase 3D Structure for Q8N100
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ATOH7 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ATOH7 purchase    MBS9320366 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the atonal homolog 7 (Drosophila) (ATOH7) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ATOH7. The ELISA analytical biochemical technique of the MBS9320366 kit is based on ATOH7 antibody-ATOH7 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ATOH7 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ATOH7. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for ATOH7. It may not necessarily be applicable to this product.
 NCBI GI #    21553337
 NCBI GeneID    220202
 NCBI Accession #    NP_660161.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_145178.3 [Other Products]
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 UniProt Primary Accession #    Q8N100 [Other Products]
 UniProt Related Accession #    Q8N100 [Other Products]
 Molecular Weight    16,871 Da
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 NCBI Official Full Name    protein atonal homolog 7
 NCBI Official Synonym Full Names    atonal homolog 7 (Drosophila)
 NCBI Official Symbol    ATOH7 [Similar Products]
 NCBI Official Synonym Symbols   
Math5; NCRNA; RNANC; PHPVAR; bHLHa13
[Similar Products]
 NCBI Protein Information    protein atonal homolog 7; helix-loop-helix protein hATH-5; class A basic helix-loop-helix protein 13
 UniProt Protein Name    Protein atonal homolog 7
 UniProt Synonym Protein Names   
Class A basic helix-loop-helix protein 13; bHLHa13; Helix-loop-helix protein hATH-5; hATH5
 Protein Family    Protein atonal
 UniProt Gene Name    ATOH7 [Similar Products]
 UniProt Synonym Gene Names    ATH5; BHLHA13; bHLHa13; hATH5 [Similar Products]
 UniProt Entry Name    ATOH7_HUMAN
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 NCBI Summary for ATOH7    This intronless gene encodes a member of the basic helix-loop-helix family of transcription factors, with similarity to Drosophila atonal gene that controls photoreceptor development. Studies in mice suggest that this gene plays a central role in retinal ganglion cell and optic nerve formation. Mutations in this gene are associated with nonsyndromic congenital retinal nonattachment. [provided by RefSeq, Dec 2011]
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 UniProt Comments for ATOH7    ATOH7: Transcription factor involved in the differentiation of retinal ganglion cells. Defects in ATOH7 are the cause of retinal non-attachment congenital non-syndromic (RNANC). A condition characterized by separation of the inner layers of the retina (neural retina) from the pigment epithelium. Clinical findings include lack of perception of light, massive retrolental mass, shallow anterior chamber, and nystagmus in otherwise normal individuals. RNANC is caused by a 6.5 kb deletion that spans a remote cis regulatory element 20 kb upstream from ATOH7.

Chromosomal Location of Human Ortholog: 10q21.3|10q21.3-q22.1

Cellular Component: nucleus

Molecular Function: protein dimerization activity; DNA binding

Biological Process: circadian rhythm; regulation of transcription, DNA-dependent; transcription, DNA-dependent; optic nerve development; entrainment of circadian clock; cell differentiation

Disease: Persistent Hyperplastic Primary Vitreous, Autosomal Recessive
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 Research Articles on ATOH7    1. Mutations within the ATOH7 gene are not implicated in the pathogenesis of optic nerve hypoplasia in our patient cohort.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with ATOH7 elisa kitOrgans/Tissues associated with ATOH7 elisa kit
 Disease Name  Pubmed Publications
 Retinal Degeneration Antibodies  >2 publications with ATOH7 and Retinal Degeneration
 Hyperplasia Antibodies  >1 publications with ATOH7 and Hyperplasia
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >56 publications with ATOH7 and Eye
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