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beta-TG elisa kit :: Human beta-Thromboglobulin (beta-TG) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS264511
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $275 +1 FREE 8GB USB
96-Strip-Wells  /  $420 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,615 +2 FREE 8GB USB
10x96-Strip-Wells  /  $2,880 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

beta-Thromboglobulin (beta-TG), ELISA Kit

 Also Known As   

Human beta-Thromboglobulin (beta-TG) ELISA Kit

 Product Synonym Names    Human b-Thromboglobulin (b-TG)  ELISA Kit
 Product Gene Name   

beta-TG elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Manual Insert    Download PDF Manual View PDF Manual
 OMIM    146930
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 Species Reactivity    Human
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 Samples    Human serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant beta-Thromboglobulin (beta-TG) concentration
 Assay Type    Sandwich
 Detection Range    2000 pg/ml-31.2 pg/ml
 Sensitivity    5pg/ml.
 Intra-assay Precision    <= 8%
 Inter-assay Precision    <= 12%
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of beta-TG elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for beta-TG purchase    MBS264511 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the beta-Thromboglobulin (beta-TG) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 2000 pg/ml-31.2 pg/ml in biological research samples containing beta-TG, with an estimated sensitivity of 5pg/ml. The ELISA analytical biochemical technique of the MBS264511 kit is based on beta-TG antibody-beta-TG antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect beta-TG antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, beta-TG. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Human serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant beta-Thromboglobulin (beta-TG) concentration. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for beta-TG elisa kit

   Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human beta-Thromboglobulin (beta-TG) monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
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 Typical Testing Data/Standard Curve (for reference only) of beta-TG elisa kit    beta-TG elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS264511
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NCBI/Uniprot data below describe general gene information for beta-TG. It may not necessarily be applicable to this product.
 NCBI GI #    179580
 NCBI GeneID    3576
 NCBI Accession #    AAA35611.1 [Other Products]
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 UniProt Secondary Accession #    Q6FGF6; Q6LAE6; Q96RG6; Q9C077; Q9UCE1; Q9UCR8; Q9UCR9; Q9UCS0; B2R4L8 [Other Products]
 UniProt Related Accession #    P10145 [Other Products]
 Molecular Weight    11,338 Da
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 NCBI Official Full Name    beta-thromboglobulin-like protein
 NCBI Official Synonym Full Names    chemokine (C-X-C motif) ligand 8
 NCBI Official Symbol    CXCL8 [Similar Products]
 NCBI Official Synonym Symbols   
IL8; NAF; GCP1; LECT; LUCT; NAP1; GCP-1; LYNAP; MDNCF; MONAP; NAP-1
[Similar Products]
 NCBI Protein Information    interleukin-8; emoctakin; interleukin 8; T-cell chemotactic factor; neutrophil-activating peptide 1; beta-thromboglobulin-like protein; granulocyte chemotactic protein 1; tumor necrosis factor-induced gene 1; alveolar macrophage chemotactic factor I; monocyte-derived neutrophil chemotactic factor; monocyte-derived neutrophil-activating peptide; small inducible cytokine subfamily B, member 8; lymphocyte derived neutrophil activating peptide; lung giant cell carcinoma-derived chemotactic protein; beta endothelial cell-derived neutrophil activating peptide
 UniProt Protein Name    Interleukin-8
 UniProt Synonym Protein Names   
C-X-C motif chemokine 8; Chemokine (C-X-C motif) ligand 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1; Monocyte-derived neutrophil chemotactic factor; MDNCF; Monocyte-derived neutrophil-activating peptide; MONAP; Neutrophil-activating protein 1; NAP-1; Protein 3-10C; T-cell chemotactic factorCleaved into the following 7 chains:MDNCF-aAlternative name(s):GCP/IL-8 protein IV; IL8/NAP1 form I
 UniProt Gene Name    CXCL8 [Similar Products]
 UniProt Synonym Gene Names    IL8; IL-8; GCP-1; MDNCF; MONAP; NAP-1; LYNAP; NAF [Similar Products]
 UniProt Entry Name    IL8_HUMAN
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 NCBI Summary for beta-TG    The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. [provided by RefSeq, Jul 2008]
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 UniProt Comments for beta-TG    IL8: IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. Belongs to the intercrine alpha (chemokine CxC) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Cytokine; Motility/polarity/chemotaxis; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4q13-q21

Cellular Component: extracellular space; extracellular region

Molecular Function: protein binding; chemokine activity; interleukin-8 receptor binding

Biological Process: regulation of cell adhesion; neutrophil chemotaxis; neutrophil activation; unfolded protein response; negative regulation of G-protein coupled receptor protein signaling pathway; calcium-mediated signaling; signal transduction; chemotaxis; regulation of retroviral genome replication; induction of positive chemotaxis; negative regulation of cell proliferation; G-protein coupled receptor protein signaling pathway; unfolded protein response, activation of signaling protein activity; cellular protein metabolic process; receptor internalization; response to molecule of bacterial origin; immune response; angiogenesis; inflammatory response; cell motility; cell cycle arrest; embryonic gut development
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 Research Articles on beta-TG    1. These results suggested that CagA is not required for Helicobacter pylori-induced activation of NF-kappaB and upregulation of IL-8 expression in gastric epithelial cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with beta-TG elisa kitDiseases associated with beta-TG elisa kit
 Products by Pathway  Pathway Diagram
 ATF-2 Transcription Factor Network Pathway antibodies  ATF-2 Transcription Factor Network Pathway Diagram
 ATF4 Activates Genes Pathway antibodies  ATF4 Activates Genes Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies  Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram
 Cellular Senescence Pathway antibodies  Cellular Senescence Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >591 publications with beta-TG and Inflammation
 Necrosis Antibodies  >313 publications with beta-TG and Necrosis
 Pulmonary Disease, Chronic Obstructive Antibodies  >78 publications with beta-TG and Pulmonary Disease, Chronic Obstructive
 Adenocarcinoma Antibodies  >30 publications with beta-TG and Adenocarcinoma
 Breast Neoplasms Antibodies  >23 publications with beta-TG and Breast Neoplasms
 Kidney Diseases Antibodies  >20 publications with beta-TG and Kidney Diseases
 Colorectal Neoplasms Antibodies  >15 publications with beta-TG and Colorectal Neoplasms
 Pulmonary Fibrosis Antibodies  >15 publications with beta-TG and Pulmonary Fibrosis
 Prostatic Neoplasms Antibodies  >14 publications with beta-TG and Prostatic Neoplasms
 Carcinoma, Squamous Cell Antibodies  >13 publications with beta-TG and Carcinoma, Squamous Cell
Organs/Tissues associated with beta-TG elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >726 publications with beta-TG and Blood
 Lung Antibodies  >229 publications with beta-TG and Lung
 Vascular Antibodies  >195 publications with beta-TG and Vascular
 Skin Antibodies  >120 publications with beta-TG and Skin
 Bone Antibodies  >68 publications with beta-TG and Bone
 Brain Antibodies  >57 publications with beta-TG and Brain
 Heart Antibodies  >50 publications with beta-TG and Heart
 Muscle Antibodies  >49 publications with beta-TG and Muscle
 Intestine Antibodies  >48 publications with beta-TG and Intestine
 Bone Marrow Antibodies  >47 publications with beta-TG and Bone Marrow
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