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BHMT2 elisa kit :: Human betaine-homocysteine methyltransferase 2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9320928 BHMT2 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

betaine-homocysteine methyltransferase 2 (BHMT2), ELISA Kit

 Also Known As   

Human Betaine--homocysteine S-methyltransferase 2, BHMT2 ELISA Kit

 Product Synonym Names    Human Betaine--homocysteine S-methyltransferase 2 (BHMT2) ELISA kit; FLJ20001; ; betaine-homocysteine methyltransferase 2
 Product Gene Name   

BHMT2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 OMIM    605932
 3D Structure    ModBase 3D Structure for Q9H2M3
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of BHMT2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for BHMT2 purchase    MBS9320928 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the betaine-homocysteine methyltransferase 2 (BHMT2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing BHMT2. The ELISA analytical biochemical technique of the MBS9320928 kit is based on BHMT2 antibody-BHMT2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect BHMT2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, BHMT2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for BHMT2. It may not necessarily be applicable to this product.
 NCBI GI #    295821189
 NCBI GeneID    23743
 NCBI Accession #    NP_001171476.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001178005.1 [Other Products]
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 UniProt Primary Accession #    Q9H2M3 [Other Products]
 UniProt Secondary Accession #    Q9NXX7; B7Z516 [Other Products]
 UniProt Related Accession #    Q9H2M3 [Other Products]
 Molecular Weight    40,354 Da
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 NCBI Official Full Name    S-methylmethionine--homocysteine S-methyltransferase BHMT2 isoform 2
 NCBI Official Synonym Full Names    betaine--homocysteine S-methyltransferase 2
 NCBI Official Symbol    BHMT2 [Similar Products]
 NCBI Protein Information    S-methylmethionine--homocysteine S-methyltransferase BHMT2; SMM-hcy methyltransferase; betaine-homocysteine methyltransferase 2
 UniProt Protein Name    S-methylmethionine--homocysteine S-methyltransferase BHMT2
 UniProt Synonym Protein Names   
Betaine--homocysteine S-methyltransferase 2
 Protein Family    S-methylmethionine--homocysteine S-methyltransferase
 UniProt Gene Name    BHMT2 [Similar Products]
 UniProt Synonym Gene Names    SMM-hcy methyltransferase [Similar Products]
 UniProt Entry Name    BHMT2_HUMAN
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 NCBI Summary for BHMT2    Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]
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 UniProt Comments for BHMT2    BHMT2: Involved in the regulation of homocysteine metabolism. Converts homocysteine to methionine using S-methylmethionine (SMM) as a methyl donor. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Methyltransferase; EC 2.1.1.10

Chromosomal Location of Human Ortholog: 5q13

Cellular Component: cytosol

Molecular Function: betaine-homocysteine S-methyltransferase activity; homocysteine S-methyltransferase activity; zinc ion binding

Biological Process: methylation; S-methylmethionine cycle; S-methylmethionine metabolic process; S-adenosylmethionine metabolic process; betaine metabolic process
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 Research Articles on BHMT2    1. No significant level of association was found with cleft lip with or without cleft palate and BHMT2 variants.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with BHMT2 elisa kitDiseases associated with BHMT2 elisa kit
 Products by Pathway  Pathway Diagram
 Glycine Betaine Degradation Pathway antibodies  Glycine Betaine Degradation Pathway Diagram
 Methionine Salvage II (mammalia) Pathway antibodies  Methionine Salvage II (mammalia) Pathway Diagram
 Superpathway Of Methionine Degradation antibodies  Superpathway Of Methionine Degradation Diagram
 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >5 publications with BHMT2 and Congenital Abnormalities
 Cleft Lip Antibodies  >5 publications with BHMT2 and Cleft Lip
 Cleft Palate Antibodies  >5 publications with BHMT2 and Cleft Palate
 Vascular Diseases Antibodies  >4 publications with BHMT2 and Vascular Diseases
 Metabolism, Inborn Errors Antibodies  >2 publications with BHMT2 and Metabolism, Inborn Errors
 Liver Diseases Antibodies  >2 publications with BHMT2 and Liver Diseases
 Cerebrovascular Disorders Antibodies  >2 publications with BHMT2 and Cerebrovascular Disorders
 Brain Diseases Antibodies  >2 publications with BHMT2 and Brain Diseases
 Neoplasms Antibodies  >1 publications with BHMT2 and Neoplasms
 Drug Toxicity Antibodies  >1 publications with BHMT2 and Drug Toxicity
Organs/Tissues associated with BHMT2 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >6 publications with BHMT2 and Liver
 Brain Antibodies  >2 publications with BHMT2 and Brain
 Kidney Antibodies  >2 publications with BHMT2 and Kidney
 Mouth Antibodies  >1 publications with BHMT2 and Mouth
 Intestine Antibodies  >1 publications with BHMT2 and Intestine
 Muscle Antibodies  >1 publications with BHMT2 and Muscle
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