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BMP4 elisa kit :: Human bone morphogenetic protein 4 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS702135
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (Limit 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

bone morphogenetic protein 4 (BMP4), ELISA Kit

 Also Known As   

Human bone morphogenetic protein 4, BMP4 ELISA Kit

 Product Synonym Names    Human bone morphogenetic protein 4 (BMP4) ELISA Kit; BMP2B; BMP2B1; MCOPS6; OFC11; ZYME; bone morphogenetic protein 2B; bone morphogenetic protein 4
 Product Gene Name   

BMP4 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS702135 Testing Data    Testing Data PDF
 OMIM    607932
 3D Structure    ModBase 3D Structure for P12644
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human BMP4. No significant cross-reactivity or interference between Human BMP4 and analogues was observed.
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 Samples    Serum, plasma, cell culture supernates
 Assay Type    Sandwich
 Detection Range    15.6 pg/ml-1000 pg/ml
 Sensitivity    3.9 pg/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
 Protein Biological Process 1    Developmental Protein
 Protein Biological Process 3    Chondrogenesis
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of BMP4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for BMP4 purchase    MBS702135 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the bone morphogenetic protein 4 (BMP4) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 15.6 pg/ml-1000 pg/ml in biological research samples containing BMP4, with an estimated sensitivity of 3.9 pg/ml. The ELISA analytical biochemical technique of the MBS702135 kit is based on BMP4 antibody-BMP4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect BMP4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, BMP4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, cell culture supernates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for BMP4 elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for BMP4 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any BMP4 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for BMP4 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of BMP4 bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of BMP4 elisa kit    BMP4 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS702135. Click to request current manual
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NCBI/Uniprot data below describe general gene information for BMP4. It may not necessarily be applicable to this product.
 NCBI GI #    157276593
 NCBI GeneID    652
 NCBI Accession #    NP_001193.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001202.3 [Other Products]
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 UniProt Primary Accession #    P12644 [Other Products]
 UniProt Secondary Accession #    Q9UM80 [Other Products]
 UniProt Related Accession #    P12644 [Other Products]
 Molecular Weight    46,555 Da
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 NCBI Official Full Name    bone morphogenetic protein 4 preproprotein
 NCBI Official Synonym Full Names    bone morphogenetic protein 4
 NCBI Official Symbol    BMP4 [Similar Products]
 NCBI Official Synonym Symbols   
ZYME; BMP2B; OFC11; BMP2B1; MCOPS6
[Similar Products]
 NCBI Protein Information    bone morphogenetic protein 4; BMP-4; BMP-2B; bone morphogenetic protein 2B
 UniProt Protein Name    Bone morphogenetic protein 4
 UniProt Synonym Protein Names   
Bone morphogenetic protein 2B; BMP-2B
 Protein Family    Bone morphogenetic protein
 UniProt Gene Name    BMP4 [Similar Products]
 UniProt Synonym Gene Names    BMP2B; DVR4; BMP-4; BMP-2B [Similar Products]
 UniProt Entry Name    BMP4_HUMAN
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 NCBI Summary for BMP4    The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein. [provided by RefSeq, Jul 2008]
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 UniProt Comments for BMP4    Function: Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction
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 Research Articles on BMP4    1. Dysregulation of transforming growth factor beta signaling, including overexpression of bone morphogenetic protein 4, may lead to a chondrocyte phenotype and may contribute to bony hypertrophy in oligoarticular juvenile idiopathic arthritis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with BMP4 elisa kitPathways associated with BMP4 elisa kit
 Reference Product  PubMed Publications
 SHH elisa kit  >244 publications with BMP4 and SHH
 BMPR2 elisa kit  >150 publications with BMP4 and BMPR2
 BMPR1A elisa kit  >149 publications with BMP4 and BMPR1A
 SMAD5 elisa kit  >78 publications with BMP4 and SMAD5
 BMPR1B elisa kit  >36 publications with BMP4 and BMPR1B
 NOG elisa kit  >20 publications with BMP4 and NOG
 SOSTDC1 elisa kit  >6 publications with BMP4 and SOSTDC1
 FST elisa kit  >4 publications with BMP4 and FST
 CHRD elisa kit  >4 publications with BMP4 and CHRD
 CHRDL1 elisa kit  >3 publications with BMP4 and CHRDL1
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Cardiac Progenitor Differentiation Pathway antibodies  Cardiac Progenitor Differentiation Pathway Diagram
 Elastic Fibre Formation Pathway antibodies  Elastic Fibre Formation Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Glypican 3 Network Pathway antibodies  Glypican 3 Network Pathway Diagram
 Heart Development Pathway antibodies  Heart Development Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
Diseases associated with BMP4 elisa kitOrgans/Tissues associated with BMP4 elisa kit
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >106 publications with BMP4 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >104 publications with BMP4 and Disease Models, Animal
 Nervous System Diseases Antibodies  >101 publications with BMP4 and Nervous System Diseases
 Heart Diseases Antibodies  >65 publications with BMP4 and Heart Diseases
 Hypertension Antibodies  >59 publications with BMP4 and Hypertension
 Brain Diseases Antibodies  >57 publications with BMP4 and Brain Diseases
 Inflammation Antibodies  >55 publications with BMP4 and Inflammation
 Lung Diseases Antibodies  >52 publications with BMP4 and Lung Diseases
 Necrosis Antibodies  >44 publications with BMP4 and Necrosis
 Kidney Diseases Antibodies  >35 publications with BMP4 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >2015 publications with BMP4 and Bone
 Muscle Antibodies  >278 publications with BMP4 and Muscle
 Eye Antibodies  >127 publications with BMP4 and Eye
 Whole Body Antibodies  >18 publications with BMP4 and Whole Body
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