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BMP6 elisa kit :: Human bone morphogenetic protein 6 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS704001
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (Limit 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $355 +1 FREE 8GB USB
96-Strip-Wells  /  $510 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,180 +2 FREE 8GB USB
10x96-Strip-Wells  /  $4,120 +5 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

bone morphogenetic protein 6 (BMP6), ELISA Kit

 Also Known As   

Human Bone Morphogenetic Protein 6, BMP-6 ELISA Kit

 Product Synonym Names    Human Bone Morphogenetic Protein 6; BMP-6 ELISA Kit; VGR; VGR1; Vg1-related sequence; vegetal related growth factor (TGFB-related) ; vegetal-related (TGFB related) cytokine; bone morphogenetic protein 6
 Product Gene Name   

BMP6 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS704001 Testing Data    Testing Data PDF
 OMIM    112266
 3D Structure    ModBase 3D Structure for P22004
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human BMP6. No significant cross-reactivity or interference between Human BMP6 and analogues was observed.
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 Samples    Serum, plasma, cell culture supernates, Cell lysates
 Detection Range    31.25 pg/ml-2000 pg/ml
 Sensitivity    7.8 pg/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
 Protein Biological Process 1    Developmental Protein
 Protein Biological Process 3    Chondrogenesis
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of BMP6 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for BMP6 purchase    MBS704001 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the bone morphogenetic protein 6 (BMP6) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 31.25 pg/ml-2000 pg/ml in biological research samples containing BMP6, with an estimated sensitivity of 7.8 pg/ml. The ELISA analytical biochemical technique of the MBS704001 kit is based on BMP6 antibody-BMP6 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect BMP6 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, BMP6. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, cell culture supernates, Cell lysates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for BMP6 elisa kit

   Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to BMP-6. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for BMP-6 and Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB (3,3',5,5' tetramethyl-benzidine) substrate solution is added to each well. Only those wells that contain BMP-6, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of BMP-6 in the samples is then determined by comparing the O.D. of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of BMP6 elisa kit    BMP6 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS704001. Click to request current manual
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NCBI/Uniprot data below describe general gene information for BMP6. It may not necessarily be applicable to this product.
 NCBI GI #    4502425
 NCBI GeneID    654
 NCBI Accession #    NP_001709.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001718.4 [Other Products]
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 UniProt Primary Accession #    P22004 [Other Products]
 UniProt Secondary Accession #    Q5TCP3 [Other Products]
 UniProt Related Accession #    P22004 [Other Products]
 Molecular Weight    57,226 Da
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 NCBI Official Full Name    bone morphogenetic protein 6 preproprotein
 NCBI Official Synonym Full Names    bone morphogenetic protein 6
 NCBI Official Symbol    BMP6 [Similar Products]
 NCBI Official Synonym Symbols   
VGR; VGR1
[Similar Products]
 NCBI Protein Information    bone morphogenetic protein 6; BMP-6; VGR-1; VG-1-R; VG-1-related protein; Vg1-related sequence; vegetal-related (TGFB related) cytokine; vegetal related growth factor (TGFB-related)
 UniProt Protein Name    Bone morphogenetic protein 6
 UniProt Synonym Protein Names   
VG-1-related protein; VG-1-R; VGR-1
 Protein Family    Bone morphogenetic protein
 UniProt Gene Name    BMP6 [Similar Products]
 UniProt Synonym Gene Names    VGR; BMP-6; VG-1-R; VGR-1 [Similar Products]
 UniProt Entry Name    BMP6_HUMAN
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 NCBI Summary for BMP6    The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity. [provided by RefSeq, Jul 2008]
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 UniProt Comments for BMP6    Function: Induces cartilage and bone formation.
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 Research Articles on BMP6    1. WNT5A derived from bone stromal cells induced the expression of BMP-6 by CaP cells; BMP-6 in turn stimulated cellular proliferation of CaP cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with BMP6 elisa kitPathways associated with BMP6 elisa kit
 Reference Product  PubMed Publications
 BMPR2 elisa kit  >58 publications with BMP6 and BMPR2
 BMPR1A elisa kit  >31 publications with BMP6 and BMPR1A
 SMAD5 elisa kit  >27 publications with BMP6 and SMAD5
 BMPR1B elisa kit  >15 publications with BMP6 and BMPR1B
 ACVR2A elisa kit  >4 publications with BMP6 and ACVR2A
 NOG elisa kit  >2 publications with BMP6 and NOG
 Products by Pathway  Pathway Diagram
 BMP Receptor Signaling Pathway antibodies  BMP Receptor Signaling Pathway Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Id Signaling Pathway antibodies  Id Signaling Pathway Diagram
 Ovarian Steroidogenesis Pathway antibodies  Ovarian Steroidogenesis Pathway Diagram
 Ovarian Steroidogenesis Pathway antibodies  Ovarian Steroidogenesis Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram
Diseases associated with BMP6 elisa kitOrgans/Tissues associated with BMP6 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >33 publications with BMP6 and Inflammation
 Anemia Antibodies  >31 publications with BMP6 and Anemia
 Disease Models, Animal Antibodies  >25 publications with BMP6 and Disease Models, Animal
 Hemochromatosis Antibodies  >23 publications with BMP6 and Hemochromatosis
 Liver Diseases Antibodies  >18 publications with BMP6 and Liver Diseases
 Adenocarcinoma Antibodies  >17 publications with BMP6 and Adenocarcinoma
 Fibrosis Antibodies  >13 publications with BMP6 and Fibrosis
 Necrosis Antibodies  >12 publications with BMP6 and Necrosis
 Nervous System Diseases Antibodies  >11 publications with BMP6 and Nervous System Diseases
 Kidney Diseases Antibodies  >11 publications with BMP6 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >59 publications with BMP6 and Blood
 Connective Tissue Antibodies  >34 publications with BMP6 and Connective Tissue
 Embryonic Tissue Antibodies  >29 publications with BMP6 and Embryonic Tissue
 Brain Antibodies  >29 publications with BMP6 and Brain
 Ovary Antibodies  >25 publications with BMP6 and Ovary
 Prostate Antibodies  >20 publications with BMP6 and Prostate
 Vascular Antibodies  >20 publications with BMP6 and Vascular
 Kidney Antibodies  >13 publications with BMP6 and Kidney
 Parathyroid Antibodies  >10 publications with BMP6 and Parathyroid
 Lung Antibodies  >9 publications with BMP6 and Lung
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