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Add To Compare List CREB1 elisa kit :: Human cAMP responsive element binding protein 1 ELISA Kit Catalog # MBS704721 Unit / Price 24-Strip-Wells (LIMIT 1) / $285 +1 FREE 8GB USB 48-Strip-Wells / $610 +1 FREE 8GB USB 96-Strip-Wells / $870 +1 FREE 8GB USB 5x96-Strip-Wells / $3,155 +3 FREE 8GB USB 10x96-Strip-Wells / $6,020 +7 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name cAMP responsive element binding protein 1 (CREB1), ELISA Kit Full Product Name Human cAMP response element-binding protein, CREB ELISA Kit Product Synonym Names Human cAMP response element-binding protein (CREB) ELISA Kit; CREB; MGC9284; OTTHUMP00000206660; active transcription factor CREB; cAMP-response element-binding protein-1; transactivator protein; cAMP responsive element binding protein 1 Product Gene Name CREB1 elisa kit[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sample Manual Insert Download Sample PDF Manual View Sample PDF Manual MBS704721 Testing Data Testing Data PDF OMIM gene 612160 3D Structure ModBase 3D Structure for P16220 Species Reactivity Human Specificity This assay has high sensitivity and excellent specificity for detection of human CREB. No significant cross-reactivity or interference between human CREB and analogues was observed. Samples Serum, plasma, tissue homogenates Assay Type Sandwich Detection Range 0.312 ng/ml -20 ng/ml. Sensitivity The minimum detectable dose of human CREB is typically less than 0.078 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Intra-assay Precision Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess. Preparation and Storage Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Product Note Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details. Other Notes Small volumes of CREB1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. Searchable Terms for CREB1 purchase MBS704721 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the cAMP responsive element binding protein 1 (CREB1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CREB1. The ELISA analytical biochemical technique of the MBS704721 kit is based on CREB1 antibody-CREB1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CREB1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CREB1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%). TOP Related Product Information for CREB1 elisa kit Principle of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for CREB has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any CREB present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for CREB is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CREB bound in the initial step. The color development is stopped and the intensity of the color is measured. Typical Testing Data/Standard Curve (for reference only) of CREB1 elisa kit TOP Sample Manual Insert of MBS704721. NCBI/Uniprot data below describe general gene information for CREB1. It may not necessarily be applicable to this product. NCBI GI # 4758054 NCBI GeneID 1385 NCBI Accession # NP_004370.1 [Other Products] NCBI GenBank Nucleotide # NM_004379.3 [Other Products] UniProt Primary Accession # P16220 [Other Products] UniProt Secondary Accession # P21934; Q6V963; Q9UMA7[Other Products] UniProt Related Accession # P16220[Other Products] Molecular Weight 36,688 Da TOP NCBI Official Full Name cyclic AMP-responsive element-binding protein 1 isoform A NCBI Official Synonym Full Names cAMP responsive element binding protein 1 NCBI Official Symbol CREB1 [Similar Products] NCBI Official Synonym Symbols CREB [Similar Products] NCBI Protein Information cyclic AMP-responsive element-binding protein 1; CREB-1; transactivator protein; active transcription factor CREB; cAMP-response element-binding protein-1; cAMP-responsive element-binding protein 1 UniProt Protein Name Cyclic AMP-responsive element-binding protein 1 Protein Family Cyclic AMP-responsive element-binding protein UniProt Gene Name CREB1 [Similar Products] UniProt Synonym Gene Names CREB-1; cAMP-responsive element-binding protein 1 [Similar Products] UniProt Entry Name CREB1_HUMAN TOP NCBI Summary for CREB1 This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] TOP UniProt Comments for CREB1 Function: Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. Research Articles on CREB1 1. Data suggest that MSK1 and MSK2 are the major CREB kinases in fibroblast-like synoviocytes from rheumatoid arthritis patients stimulated with lysophosphatidic acid and that phosphorylation of CREB1 at Ser-133 plays a significant role in IL-8 production. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with CREB1 elisa kit Reference Product PubMed Publications JUN elisa kit >150 publications with CREB1 and JUN FOS elisa kit >51 publications with CREB1 and FOS CREBBP elisa kit >21 publications with CREB1 and CREBBP EP300 elisa kit >9 publications with CREB1 and EP300 AKT1 elisa kit >8 publications with CREB1 and AKT1 RPS6KA1 elisa kit >4 publications with CREB1 and RPS6KA1 RPS6KA5 elisa kit >1 publications with CREB1 and RPS6KA5 Pathways associated with CREB1 elisa kit Products by Pathway Pathway Diagram AKT Phosphorylates Targets In The Nucleus Pathway antibodies AKT Phosphorylates Targets In The Nucleus Pathway Diagram AMPK Signaling Pathway antibodies AMPK Signaling Pathway Diagram AMPK Signaling Pathway antibodies AMPK Signaling Pathway Diagram ATF-2 Transcription Factor Network Pathway antibodies ATF-2 Transcription Factor Network Pathway Diagram ATM Signaling Pathway antibodies ATM Signaling Pathway Diagram Activated TLR4 Signalling Pathway antibodies Activated TLR4 Signalling Pathway Diagram Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway antibodies Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway Diagram Adaptive Immune System Pathway antibodies Adaptive Immune System Pathway Diagram Adipogenesis Pathway antibodies Adipogenesis Pathway Diagram Adrenergic Signaling In Cardiomyocytes Pathway antibodies Adrenergic Signaling In Cardiomyocytes Pathway Diagram Diseases associated with CREB1 elisa kit Disease Name Pubmed Publications Nervous System Diseases Antibodies >100 publications with CREB1 and Nervous System Diseases Inflammation Antibodies >63 publications with CREB1 and Inflammation Depressive Disorder Antibodies >42 publications with CREB1 and Depressive Disorder Necrosis Antibodies >41 publications with CREB1 and Necrosis Memory Disorders Antibodies >39 publications with CREB1 and Memory Disorders Learning Disorders Antibodies >29 publications with CREB1 and Learning Disorders Lung Neoplasms Antibodies >24 publications with CREB1 and Lung Neoplasms Atherosclerosis Antibodies >20 publications with CREB1 and Atherosclerosis Cognition Disorders Antibodies >18 publications with CREB1 and Cognition Disorders Liver Diseases Antibodies >17 publications with CREB1 and Liver Diseases Organs/Tissues associated with CREB1 elisa kit Organ/Tissue Name Pubmed Publications Brain Antibodies >179 publications with CREB1 and Brain Blood Antibodies >96 publications with CREB1 and Blood Muscle Antibodies >44 publications with CREB1 and Muscle Bone Antibodies >42 publications with CREB1 and Bone Lung Antibodies >40 publications with CREB1 and Lung Vascular Antibodies >35 publications with CREB1 and Vascular Heart Antibodies >26 publications with CREB1 and Heart Liver Antibodies >26 publications with CREB1 and Liver Kidney Antibodies >19 publications with CREB1 and Kidney Bone Marrow Antibodies >18 publications with CREB1 and Bone Marrow TOP © 2006-24 MyBioSource.com. 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