NP_001207418.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
78,287 Da
NCBI Official Full Name
cadherin-13 isoform 3
NCBI Official Synonym Full Names
cadherin 13
NCBI Official Synonym Symbols
NCBI Protein Information
cadherin-13; T-cad; T-cadherin; heart cadherin; H-cadherin (heart); cadherin 13, H-cadherin (heart)
UniProt Protein Name
Cadherin-13
UniProt Synonym Protein Names
Heart cadherin; H-cadherin; P105; Truncated cadherin; T-cad; T-cadherin
UniProt Synonym Gene Names
UniProt Entry Name
CAD13_HUMAN
NCBI Summary for CDH13
This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2011]
UniProt Comments for CDH13
Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth.1 PublicationManual assertion based on experiment in:Ref.9
Research Articles on CDH13
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Products associated with CDH13 elisa kit
Pathways associated with CDH13 elisa kit
Diseases associated with CDH13 elisa kit
Organs/Tissues associated with CDH13 elisa kit
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