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CDH2 elisa kit :: Human cadherin 2, type 1, N-cadherin (neuronal) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS703223
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $550 +1 FREE 8GB USB
96-Strip-Wells  /  $795 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,890 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,465 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

cadherin 2, type 1, N-cadherin (neuronal) (CDH2), ELISA Kit

★Popular Item★
 Also Known As   

Human Neural -Cadherin, N-Cad ELISA Kit

 Product Synonym Names    Human Neural -Cadherin; N-Cad ELISA kit; CD325; CDHN; CDw325; NCAD; N-cadherin 1; cadherin 2; N-cadherin (neuronal) ; cadherin 2; type 1; calcium-dependent adhesion protein; neuronal; neural cadherin; cadherin 2; type 1; N-cadherin (neuronal)
 Product Gene Name   

CDH2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS703223 Testing Data    Testing Data PDF
 OMIM    114020
 3D Structure    ModBase 3D Structure for P19022
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of human N-Cad. No significant cross-reactivity or interference between human N-Cad and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates
 Assay Type    Sandwich
 Detection Range    6.25 ng/ml -400 ng/ml.
 Sensitivity    The minimum detectable dose of human N-Cad is typically less than 1.56 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CDH2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CDH2 purchase    MBS703223 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the cadherin 2, type 1, N-cadherin (neuronal) (CDH2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 6.25 ng/ml -400 ng/ml in biological research samples containing CDH2, with an estimated sensitivity of The minimum detectable dose of human N-Cad is typically less than 1.56 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. The ELISA analytical biochemical technique of the MBS703223 kit is based on CDH2 antibody-CDH2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CDH2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CDH2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for CDH2 elisa kit

   Principle of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for N-Cad has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any N-Cad present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for N-Cad is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of N-Cad bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of CDH2 elisa kit    CDH2 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS703223. Click to request current manual
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NCBI/Uniprot data below describe general gene information for CDH2. It may not necessarily be applicable to this product.
 NCBI GI #    14589889
 NCBI GeneID    1000
 NCBI Accession #    NP_001783.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001792.3 [Other Products]
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 UniProt Primary Accession #    P19022 [Other Products]
 UniProt Secondary Accession #    Q14923; Q8N173; B0YIY6 [Other Products]
 UniProt Related Accession #    P19022 [Other Products]
 Molecular Weight    99,809 Da
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 NCBI Official Full Name    cadherin-2 preproprotein
 NCBI Official Synonym Full Names    cadherin 2, type 1, N-cadherin (neuronal)
 NCBI Official Symbol    CDH2 [Similar Products]
 NCBI Official Synonym Symbols   
CDHN; NCAD; CD325; CDw325
[Similar Products]
 NCBI Protein Information    cadherin-2; N-cadherin 1; neural cadherin; neural-cadherin; cadherin 2, N-cadherin (neuronal); calcium-dependent adhesion protein, neuronal
 UniProt Protein Name    Cadherin-2
 UniProt Synonym Protein Names   
CDw325; Neural cadherin; N-cadherin; CD_antigen: CD325
 Protein Family    Cadherin
 UniProt Gene Name    CDH2 [Similar Products]
 UniProt Synonym Gene Names    CDHN; NCAD; N-cadherin [Similar Products]
 UniProt Entry Name    CADH2_HUMAN
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 NCBI Summary for CDH2    This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CDH2    Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density
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 Research Articles on CDH2    1. N-cadherin had no diagnostic value in arrhythmogenic right ventricular cardiomyopathy.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CDH2 elisa kitPathways associated with CDH2 elisa kit
 Reference Product  PubMed Publications
 CTNNB1 elisa kit  >67 publications with CDH2 and CTNNB1
 MMP9 elisa kit  >10 publications with CDH2 and MMP9
 JUP elisa kit  >4 publications with CDH2 and JUP
 CTNNA1 elisa kit  >2 publications with CDH2 and CTNNA1
 CTNND1 elisa kit  >2 publications with CDH2 and CTNND1
 SPAG9 elisa kit  >1 publications with CDH2 and SPAG9
 LRP5 elisa kit  >1 publications with CDH2 and LRP5
 FGFR1 elisa kit  >1 publications with CDH2 and FGFR1
 Products by Pathway  Pathway Diagram
 Adherens Junctions Interactions Pathway antibodies  Adherens Junctions Interactions Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 CDO In Myogenesis Pathway antibodies  CDO In Myogenesis Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Junction Organization Pathway antibodies  Cell Junction Organization Pathway Diagram
 Cell-Cell Communication Pathway antibodies  Cell-Cell Communication Pathway Diagram
Diseases associated with CDH2 elisa kitOrgans/Tissues associated with CDH2 elisa kit
 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >37 publications with CDH2 and Neoplasm Metastasis
 Disease Progression Antibodies  >30 publications with CDH2 and Disease Progression
 Breast Neoplasms Antibodies  >24 publications with CDH2 and Breast Neoplasms
 Lung Neoplasms Antibodies  >20 publications with CDH2 and Lung Neoplasms
 Disease Models, Animal Antibodies  >19 publications with CDH2 and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >18 publications with CDH2 and Cardiovascular Diseases
 Prostatic Neoplasms Antibodies  >13 publications with CDH2 and Prostatic Neoplasms
 Heart Diseases Antibodies  >13 publications with CDH2 and Heart Diseases
 Liver Diseases Antibodies  >12 publications with CDH2 and Liver Diseases
 Neoplasms, Experimental Antibodies  >12 publications with CDH2 and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >30 publications with CDH2 and Brain
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