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CDH4 elisa kit :: Human cadherin 4, type 1, R-cadherin (retinal) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS906401 CDH4 elisa kit
Unit / Price
24-Strip-Wells (Limit 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

cadherin 4, type 1, R-cadherin (retinal) (CDH4), ELISA Kit

 Also Known As   

Human Cadherin-4, CDH4 ELISA Kit

 Product Synonym Names    Human Cadherin-4 (CDH4) ELISA kit; CAD4; FLJ22202; FLJ40547; MGC126700; MGC138355; RCAD; R-cadherin; cadherin 4; type 1; cadherin 4; type 1; preproprotein; retinal cadherin; cadherin 4; type 1; R-cadherin (retinal)
 Product Gene Name   

CDH4 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 OMIM    603006
 3D Structure    ModBase 3D Structure for P55283
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human CDH4. No significant cross-reactivity or interference between Human CDH4 and analogues was observed.
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 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
 Protein Biological Process 1    Cell Adhesion
 Protein Biological Process 3    Cell adhesion
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of CDH4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CDH4 purchase    MBS906401 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the cadherin 4, type 1, R-cadherin (retinal) (CDH4) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CDH4. The ELISA analytical biochemical technique of the MBS906401 kit is based on CDH4 antibody-CDH4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CDH4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CDH4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for CDH4. It may not necessarily be applicable to this product.
 NCBI GI #    356640224
 NCBI GeneID    1002
 NCBI Accession #    NP_001239268.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001252339.2 [Other Products]
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 UniProt Primary Accession #    P55283 [Other Products]
 UniProt Secondary Accession #    Q2M208; Q5VZ44; Q9BZ05; B3KWB8; G3V1P8 [Other Products]
 UniProt Related Accession #    P55283 [Other Products]
 Molecular Weight    100,281 Da
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 NCBI Official Full Name    cadherin-4 isoform 3
 NCBI Official Synonym Full Names    cadherin 4, type 1, R-cadherin (retinal)
 NCBI Official Symbol    CDH4 [Similar Products]
 NCBI Official Synonym Symbols   
CAD4; RCAD; R-CAD
[Similar Products]
 NCBI Protein Information    cadherin-4; R-cadherin; retinal cadherin; cadherin 4, type 1, preproprotein
 UniProt Protein Name    Cadherin-4
 UniProt Synonym Protein Names   
Retinal cadherin; R-CAD; R-cadherin
 UniProt Gene Name    CDH4 [Similar Products]
 UniProt Synonym Gene Names    R-CAD; R-cadherin [Similar Products]
 UniProt Entry Name    CADH4_HUMAN
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 NCBI Summary for CDH4    This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
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 UniProt Comments for CDH4    CDH4: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May play an important role in retinal development. Expressed mainly in brain but also found in other tissues.

Protein type: Motility/polarity/chemotaxis; Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 20q13.3

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: calcium ion binding

Biological Process: heterophilic cell adhesion; intercellular junction assembly and maintenance; axon guidance; positive regulation of axon extension; homophilic cell adhesion; cell adhesion
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 Research Articles on CDH4    1. P-cadherin expression correlated with tumor progression and could be an independent predictor for bladder cancer survival.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CDH4 elisa kitPathways associated with CDH4 elisa kit
 Reference Product  PubMed Publications
 CDH2 elisa kit  >3 publications with CDH4 and CDH2
 Products by Pathway  Pathway Diagram
 Adherens Junctions Interactions Pathway antibodies  Adherens Junctions Interactions Pathway Diagram
 CDO In Myogenesis Pathway antibodies  CDO In Myogenesis Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Junction Organization Pathway antibodies  Cell Junction Organization Pathway Diagram
 Cell-Cell Communication Pathway antibodies  Cell-Cell Communication Pathway Diagram
 Cell-cell Junction Organization Pathway antibodies  Cell-cell Junction Organization Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Myogenesis Pathway antibodies  Myogenesis Pathway Diagram
Diseases associated with CDH4 elisa kitOrgans/Tissues associated with CDH4 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >5 publications with CDH4 and Neoplasms
 Inflammation Antibodies  >3 publications with CDH4 and Inflammation
 Stomach Neoplasms Antibodies  >2 publications with CDH4 and Stomach Neoplasms
 Gastrointestinal Neoplasms Antibodies  >2 publications with CDH4 and Gastrointestinal Neoplasms
 Gastrointestinal Diseases Antibodies  >2 publications with CDH4 and Gastrointestinal Diseases
 Hypertension Antibodies  >2 publications with CDH4 and Hypertension
 Carcinoma Antibodies  >2 publications with CDH4 and Carcinoma
 Hypercholesterolemia Antibodies  >1 publications with CDH4 and Hypercholesterolemia
 Hypertrophy Antibodies  >1 publications with CDH4 and Hypertrophy
 Necrosis Antibodies  >1 publications with CDH4 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >9 publications with CDH4 and Brain
 Eye Antibodies  >6 publications with CDH4 and Eye
 Blood Antibodies  >4 publications with CDH4 and Blood
 Lung Antibodies  >2 publications with CDH4 and Lung
 Embryonic Tissue Antibodies  >2 publications with CDH4 and Embryonic Tissue
 Heart Antibodies  >1 publications with CDH4 and Heart
 Muscle Antibodies  >1 publications with CDH4 and Muscle
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