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CANT1 elisa kit :: Human calcium activated nucleotidase 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9336482 CANT1 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

calcium activated nucleotidase 1 (CANT1), ELISA Kit

 Also Known As   

Human Soluble calcium-activated nucleotidase 1, CANT1 ELISA Kit

 Product Synonym Names    Human Soluble calcium-activated nucleotidase 1 (CANT1) ELISA kit; DBQD; SCAN-1; SCAN1; SHAPY; Ca2+-dependent endoplasmic reticulum nucleoside diphosphatase; Soluble Ca-Activated Nucleotidase; isozyme 1; apyrase; soluble calcium-activated nucleotidase SCAN-1; calcium activated nucleotidase 1
 Product Gene Name   

CANT1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    613165
 3D Structure    ModBase 3D Structure for Q8WVQ1
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CANT1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CANT1 purchase    MBS9336482 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the calcium activated nucleotidase 1 (CANT1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CANT1. The ELISA analytical biochemical technique of the MBS9336482 kit is based on CANT1 antibody-CANT1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CANT1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CANT1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for CANT1. It may not necessarily be applicable to this product.
 NCBI GI #    229577440
 NCBI GeneID    124583
 NCBI Accession #    NP_001153244.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001159772.1 [Other Products]
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 UniProt Primary Accession #    Q8WVQ1 [Other Products]
 UniProt Secondary Accession #    Q7Z2J7; Q8NG05; Q8NHP0; Q9BSD5; B4DJ54 [Other Products]
 UniProt Related Accession #    Q8WVQ1 [Other Products]
 Molecular Weight    44,840 Da
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 NCBI Official Full Name    soluble calcium-activated nucleotidase 1
 NCBI Official Synonym Full Names    calcium activated nucleotidase 1
 NCBI Official Symbol    CANT1 [Similar Products]
 NCBI Official Synonym Symbols   
DBQD; SCAN1; SHAPY; SCAN-1
[Similar Products]
 NCBI Protein Information    soluble calcium-activated nucleotidase 1; apyrase homolog; putative MAPK-activating protein PM09; putative NF-kappa-B-activating protein 107; soluble Ca-activated nucleotidase, isozyme 1; soluble calcium-activated nucleotidase SCAN-1; Ca2+-dependent endoplasmic reticulum nucleoside diphosphatase; micromelic dwarfism with vertebral and metaphyseal abnormalities and advanced carpotarsal ossification
 UniProt Protein Name    Soluble calcium-activated nucleotidase 1
 UniProt Synonym Protein Names   
Apyrase homolog; Putative MAPK-activating protein PM09; Putative NF-kappa-B-activating protein 107
 Protein Family    Soluble calcium-activated nucleotidase
 UniProt Gene Name    CANT1 [Similar Products]
 UniProt Synonym Gene Names    SHAPY; SCAN-1 [Similar Products]
 UniProt Entry Name    CANT1_HUMAN
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 NCBI Summary for CANT1    This protein encoded by this gene belongs to the apyrase family. It functions as a calcium-dependent nucleotidase with a preference for UDP. Mutations in this gene are associated with Desbuquois dysplasia with hand anomalies. Alternatively spliced transcript variants have been noted for this gene.[provided by RefSeq, Mar 2010]
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 UniProt Comments for CANT1    CANT1: Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP. Involved in proteoglycan synthesis. Defects in CANT1 are the cause of Desbuquois dysplasia (DBQD). A chondrodysplasia characterized by severe prenatal and postnatal growth retardation (less than -5 SD), joint laxity, short extremities, progressive scoliosis, round face, midface hypoplasia, prominent bulging eyes. The main radiologic features are short long bones with metaphyseal splay, a 'Swedish key' appearance of the proximal femur (exaggerated trochanter), and advance carpal and tarsal bone age. Two forms of Desbuquois dysplasia are distinguished on the basis of the presence (type 1) or absence (type 2) of characteristic hand anomalies: an extra ossification center distal to the second metacarpal, delta phalanx, bifid distal thumb phalanx, and phalangeal dislocations. Belongs to the apyrase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; Endoplasmic reticulum; Membrane protein, integral; Nucleotide Metabolism - pyrimidine; Nucleotide Metabolism - purine; EC 3.6.1.6

Chromosomal Location of Human Ortholog: 17q25.3

Cellular Component: endoplasmic reticulum membrane; integral to membrane

Molecular Function: signal transducer activity; calcium ion binding; uridine-diphosphatase activity

Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; proteoglycan biosynthetic process; signal transduction

Disease: Desbuquois Dysplasia 1
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 Research Articles on CANT1    1. Data studied proteoglycan synthesis in CANT1 mutated patient fibroblasts, and found significant reduced GAG synthesis in presence of beta-D-xyloside, suggesting that CANT1 plays a role in proteoglycan metabolism.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with CANT1 elisa kitDiseases associated with CANT1 elisa kit
 Products by Pathway  Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram
 Disease Name  Pubmed Publications
 Bone Diseases, Developmental Antibodies  >4 publications with CANT1 and Bone Diseases, Developmental
 Congenital Abnormalities Antibodies  >3 publications with CANT1 and Congenital Abnormalities
 Prostatic Diseases Antibodies  >3 publications with CANT1 and Prostatic Diseases
 Desbuquois syndrome Antibodies  >2 publications with CANT1 and Desbuquois syndrome
 Growth Disorders Antibodies  >1 publications with CANT1 and Growth Disorders
 Fetal Diseases Antibodies  >1 publications with CANT1 and Fetal Diseases
 Pregnancy Complications Antibodies  >1 publications with CANT1 and Pregnancy Complications
 Edema Antibodies  >1 publications with CANT1 and Edema
 Fetal Death Antibodies  >1 publications with CANT1 and Fetal Death
Organs/Tissues associated with CANT1 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >3 publications with CANT1 and Bone
 Prostate Antibodies  >3 publications with CANT1 and Prostate
 Lung Antibodies  >1 publications with CANT1 and Lung
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