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CPT1A elisa kit :: Human carnitine palmitoyltransferase 1A (liver) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9332032 CPT1A elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

carnitine palmitoyltransferase 1A (liver) (CPT1A), ELISA Kit

★Popular Item★
 Also Known As   

Human Carnitine O-palmitoyltransferase 1, liver isoform, CPT1A/CPT1 ELISA Kit

 Product Synonym Names    Human Carnitine O-palmitoyltransferase 1; liver isoform (CPT1A/CPT1) ELISA kit; CPT1; CPT1-L; L-CPT1; carnitine palmitoyltransferase 1A liver; carnitine palmitoyltransferase I; liver; carnitine palmitoyltransferase 1A (liver)
 Product Gene Name   

CPT1A elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    600528
 3D Structure    ModBase 3D Structure for P50416
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 Species Reactivity    Human
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Undiluted original Human body fluids, tissue homogenates, secretions or feces samples.
 Assay Type    Sandwich
 Detection Range    1.56ng/ml-50ng/ml.
 Sensitivity    0.1ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CPT1A elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CPT1A purchase    MBS9332032 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the carnitine palmitoyltransferase 1A (liver) (CPT1A) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 1.56ng/ml-50ng/ml in biological research samples containing CPT1A, with an estimated sensitivity of 0.1ng/ml. The ELISA analytical biochemical technique of the MBS9332032 kit is based on CPT1A antibody-CPT1A antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CPT1A antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CPT1A. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for CPT1A elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CPT1A (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9332032. Click to request current manual
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NCBI/Uniprot data below describe general gene information for CPT1A. It may not necessarily be applicable to this product.
 NCBI GI #    73623028
 NCBI GeneID    1374
 NCBI Accession #    NP_001027017.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001031847.2 [Other Products]
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 UniProt Primary Accession #    P50416 [Other Products]
 UniProt Secondary Accession #    Q8TCU0; Q9BWK0 [Other Products]
 UniProt Related Accession #    P50416 [Other Products]
 Molecular Weight    88,368 Da
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 NCBI Official Full Name    carnitine O-palmitoyltransferase 1, liver isoform isoform 2
 NCBI Official Synonym Full Names    carnitine palmitoyltransferase 1A (liver)
 NCBI Official Symbol    CPT1A [Similar Products]
 NCBI Official Synonym Symbols   
CPT1; CPT1-L; L-CPT1
[Similar Products]
 NCBI Protein Information    carnitine O-palmitoyltransferase 1, liver isoform; CPT I; CPTI-L; carnitine palmitoyltransferase I, liver; carnitine O-palmitoyltransferase I, liver isoform
 UniProt Protein Name    Carnitine O-palmitoyltransferase 1, liver isoform
 UniProt Synonym Protein Names   
Carnitine O-palmitoyltransferase I, liver isoform; CPT I; CPTI-L; Carnitine palmitoyltransferase 1A
 Protein Family    Carnitine O-palmitoyltransferase
 UniProt Gene Name    CPT1A [Similar Products]
 UniProt Synonym Gene Names    CPT1; CPT1-L; CPT I; CPTI-L [Similar Products]
 UniProt Entry Name    CPT1A_HUMAN
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 NCBI Summary for CPT1A    The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CPT1A    Function: Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Plays an important role in triglyceride metabolism.

Catalytic activity: Palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine.2 PublicationsManual assertion based on experiment in:Ref.11

Enzyme regulation: Inhibited by malonyl-CoA.1 PublicationManual assertion based on experiment in:Ref.13
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 Research Articles on CPT1A    1. The results suggest the generality of carnitine palmitoyltransferase-1 inhibition under various stress conditions associated with ROS generation, providing an insight into a mechanism for oxidative dysfunction in mitochondrial metabolism.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with CPT1A elisa kitDiseases associated with CPT1A elisa kit
 Products by Pathway  Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Circadian Clock Pathway antibodies  Circadian Clock Pathway Diagram
 FOXA2 And FOXA3 Transcription Factor Networks Pathway antibodies  FOXA2 And FOXA3 Transcription Factor Networks Pathway Diagram
 Fatty Acid Beta Oxidation Pathway antibodies  Fatty Acid Beta Oxidation Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Import Of Palmitoyl-CoA Into The Mitochondrial Matrix Pathway antibodies  Import Of Palmitoyl-CoA Into The Mitochondrial Matrix Pathway Diagram
 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >47 publications with CPT1A and Fatty Liver
 Liver Diseases Antibodies  >22 publications with CPT1A and Liver Diseases
 Obesity Antibodies  >20 publications with CPT1A and Obesity
 Insulin Resistance Antibodies  >16 publications with CPT1A and Insulin Resistance
 Neoplasms Antibodies  >11 publications with CPT1A and Neoplasms
 Hyperinsulinism Antibodies  >11 publications with CPT1A and Hyperinsulinism
 Inflammation Antibodies  >8 publications with CPT1A and Inflammation
 Liver Neoplasms Antibodies  >6 publications with CPT1A and Liver Neoplasms
 Diabetes Mellitus Antibodies  >6 publications with CPT1A and Diabetes Mellitus
 Carcinoma, Hepatocellular Antibodies  >4 publications with CPT1A and Carcinoma, Hepatocellular
Organs/Tissues associated with CPT1A elisa kit
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >65 publications with CPT1A and Liver
 Blood Antibodies  >31 publications with CPT1A and Blood
 Muscle Antibodies  >25 publications with CPT1A and Muscle
 Brain Antibodies  >9 publications with CPT1A and Brain
 Kidney Antibodies  >7 publications with CPT1A and Kidney
 Connective Tissue Antibodies  >4 publications with CPT1A and Connective Tissue
 Vascular Antibodies  >2 publications with CPT1A and Vascular
 Bone Antibodies  >2 publications with CPT1A and Bone
 Skin Antibodies  >2 publications with CPT1A and Skin
 Bone Marrow Antibodies  >2 publications with CPT1A and Bone Marrow
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