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CTSS elisa kit :: Human cathepsin S ELISA Kit

Scan QR to view Datasheet Catalog #    MBS705148 (SPECIAL PROMOTIONAL PRICING for a limited time)
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $625 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,595 +3 FREE 8GB USB
10x96-Strip-Wells  /  $4,905 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

cathepsin S (CTSS), ELISA Kit

★Popular Item★
 Also Known As   

Human Cathepsin S, CTSS ELISA Kit

 Product Synonym Names    Human Cathepsin S (CTSS) ELISA Kit; MGC3886; ; cathepsin S
 Product Gene Name   

CTSS elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS705148 Testing Data    Testing Data PDF
 OMIM    116845
 3D Structure    ModBase 3D Structure for P25774
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human CTSS. No significant cross-reactivity or interference between Human CTSS and analogues was observed.
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 Samples    Serum, plasma, cell culture supernates, tissue homogenates, Cell lysates
 Detection Range    1.25 ng/ml-80 ng/ml
 Sensitivity    0.31 ng/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CTSS elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CTSS purchase    MBS705148 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the cathepsin S (CTSS) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 1.25 ng/ml-80 ng/ml in biological research samples containing CTSS, with an estimated sensitivity of 0.31 ng/ml. The ELISA analytical biochemical technique of the MBS705148 kit is based on CTSS antibody-CTSS antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CTSS antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CTSS. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, cell culture supernates, tissue homogenates, Cell lysates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for CTSS elisa kit

   Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to CTSS. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for CTSS and Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB (3,3',5,5' tetramethyl-benzidine) substrate solution is added to each well. Only those wells that contain CTSS, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of CTSS in the samples is then determined by comparing the O.D. of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of CTSS elisa kit    CTSS elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS705148. Click to request current manual
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NCBI/Uniprot data below describe general gene information for CTSS. It may not necessarily be applicable to this product.
 NCBI GI #    315075311
 NCBI GeneID    1520
 NCBI Accession #    NP_001186668.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001199739.1 [Other Products]
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 UniProt Primary Accession #    P25774 [Other Products]
 UniProt Secondary Accession #    Q5T5I0; Q6FHS5; Q9BUG3; B4DWC9; D3DV05 [Other Products]
 UniProt Related Accession #    P25774 [Other Products]
 Molecular Weight    37,496 Da
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 NCBI Official Full Name    cathepsin S isoform 2 preproprotein
 NCBI Official Synonym Full Names    cathepsin S
 NCBI Official Symbol    CTSS [Similar Products]
 NCBI Protein Information    cathepsin S
 UniProt Protein Name    Cathepsin S
 Protein Family    Cathepsin
 UniProt Gene Name    CTSS [Similar Products]
 UniProt Entry Name    CATS_HUMAN
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 NCBI Summary for CTSS    The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The encoded protein can function as an elastase over a broad pH range in alveolar macrophages. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
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 UniProt Comments for CTSS    Function: Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.

Catalytic activity: Similar to cathepsin L, but with much less activity on Z-Phe-Arg-|-NHMec, and more activity on the Z-Val-Val-Arg-|-Xaa compound.
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 Research Articles on CTSS    1. catalase expression (or activity) was higher, while intracellular and extracellular Cat S, Cat L, and Cat K activities were lower in the non-invasive CL1-0 cells compared to the highly invasive CL1-5 cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CTSS elisa kitPathways associated with CTSS elisa kit
 Reference Product  PubMed Publications
 CTSD elisa kit  >3 publications with CTSS and CTSD
 CD53 elisa kit  >2 publications with CTSS and CD53
 TLR7 elisa kit  >1 publications with CTSS and TLR7
 B2M elisa kit  >1 publications with CTSS and B2M
 LGMN elisa kit  >1 publications with CTSS and LGMN
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing-Cross Presentation Pathway antibodies  Antigen Processing-Cross Presentation Pathway Diagram
 Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway antibodies  Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway Diagram
 Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies  Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
 Collagen Formation Pathway antibodies  Collagen Formation Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 Endosomal/Vacuolar Pathway antibodies  Endosomal/Vacuolar Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
Diseases associated with CTSS elisa kitOrgans/Tissues associated with CTSS elisa kit
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >17 publications with CTSS and Nervous System Diseases
 Inflammation Antibodies  >12 publications with CTSS and Inflammation
 Cardiovascular Diseases Antibodies  >9 publications with CTSS and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >9 publications with CTSS and Disease Models, Animal
 Obesity Antibodies  >9 publications with CTSS and Obesity
 Atherosclerosis Antibodies  >6 publications with CTSS and Atherosclerosis
 Hypertension Antibodies  >3 publications with CTSS and Hypertension
 Kidney Diseases Antibodies  >3 publications with CTSS and Kidney Diseases
 Necrosis Antibodies  >3 publications with CTSS and Necrosis
 Lung Diseases Antibodies  >3 publications with CTSS and Lung Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >12 publications with CTSS and Blood
 Brain Antibodies  >10 publications with CTSS and Brain
 Vascular Antibodies  >8 publications with CTSS and Vascular
 Muscle Antibodies  >6 publications with CTSS and Muscle
 Trachea Antibodies  >4 publications with CTSS and Trachea
 Adipose Tissue Antibodies  >4 publications with CTSS and Adipose Tissue
 Kidney Antibodies  >4 publications with CTSS and Kidney
 Connective Tissue Antibodies  >4 publications with CTSS and Connective Tissue
 Lung Antibodies  >3 publications with CTSS and Lung
 Embryonic Tissue Antibodies  >3 publications with CTSS and Embryonic Tissue
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