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CCR2 elisa kit :: Human chemokine (C-C motif) receptor 2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS700302
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $550 +1 FREE 8GB USB
96-Strip-Wells  /  $795 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,890 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,465 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

chemokine (C-C motif) receptor 2 (CCR2), ELISA Kit

★Popular Item★
 Also Known As   

Human CC-Chemokine Receptor 2, CCR2 ELISA Kit

 Product Synonym Names    Human CC-Chemokine Receptor 2; CCR2 ELISA Kit; CC-CKR-2; CCR2A; CCR2B; CD192; CKR2; CKR2A; CKR2B; CMKBR2; MCP-1-R; MCP-1 receptor; chemokine (C-C) receptor 2; monocyte chemoattractant protein 1 receptor; monocyte chemotactic protein 1 receptor; chemokine (C-C motif) receptor 2
 Product Gene Name   

CCR2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS700302 Testing Data    Testing Data PDF
 OMIM    gene 609423
 3D Structure    ModBase 3D Structure for P41597
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of human CCR2. No significant cross-reactivity or interference between human CCR2 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates, cerebrospinal fluid (CSF)
 Assay Type    Quantitative Sandwich
 Detection Range    23.44 pg/ml -1500 pg/ml
 Sensitivity    Typically less than 5.86 pg/ml.
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CCR2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CCR2 purchase    MBS700302 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the chemokine (C-C motif) receptor 2 (CCR2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 23.44 pg/ml -1500 pg/ml in biological research samples containing CCR2, with an estimated sensitivity of Typically less than 5.86 pg/ml. The ELISA analytical biochemical technique of the MBS700302 kit is based on CCR2 antibody-CCR2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CCR2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CCR2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates, cerebrospinal fluid (CSF). Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for CCR2 elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for CCR2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any CCR2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for CCR2 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CCR2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of CCR2 elisa kit    CCR2 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS700302. Click to request current manual
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NCBI/Uniprot data below describe general gene information for CCR2. It may not necessarily be applicable to this product.
 NCBI GI #    183979980
 NCBI GeneID    729230
 NCBI Accession #    NP_001116513.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001123041.2 [Other Products]
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 UniProt Primary Accession #    P41597 [Other Products]
 UniProt Secondary Accession #    Q4VBL2; A0AVQ3; B2RMT0 [Other Products]
 UniProt Related Accession #    P41597 [Other Products]
 Molecular Weight    41,915 Da
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 NCBI Official Full Name    C-C chemokine receptor type 2 isoform A
 NCBI Official Synonym Full Names    chemokine (C-C motif) receptor 2
 NCBI Official Symbol    CCR2 [Similar Products]
 NCBI Official Synonym Symbols   
CKR2; CCR-2; CCR2A; CCR2B; CD192; CKR2A; CKR2B; CMKBR2; MCP-1-R; CC-CKR-2
[Similar Products]
 NCBI Protein Information    C-C chemokine receptor type 2; MCP-1 receptor; monocyte chemotactic protein 1 receptor; monocyte chemoattractant protein 1 receptor
 UniProt Protein Name    C-C chemokine receptor type 2
 UniProt Synonym Protein Names   
Monocyte chemoattractant protein 1 receptor; MCP-1-R; CD_antigen: CD192
 Protein Family    C-C chemokine receptor
 UniProt Gene Name    CCR2 [Similar Products]
 UniProt Synonym Gene Names    CMKBR2; C-C CKR-2; CC-CKR-2; CCR-2; CCR2; MCP-1-R [Similar Products]
 UniProt Entry Name    CCR2_HUMAN
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 NCBI Summary for CCR2    This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009]
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 UniProt Comments for CCR2    Function: Receptor for the CCL2, CCL7 and CCL13 chemokines. Transduces a signal by increasing intracellular calcium ion levels. Alternative coreceptor with CD4 for HIV-1 infection.1 PublicationManual assertion based on experiment in:Ref.14
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 Research Articles on CCR2    1. Findings suggests that CCR2 expression is crucial for CCL2-induced proliferation and invasion of PC-3M cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CCR2 elisa kitPathways associated with CCR2 elisa kit
 Reference Product  PubMed Publications
 CCL2 elisa kit  >1202 publications with CCR2 and CCL2
 CCL5 elisa kit  >217 publications with CCR2 and CCL5
 CXCL12 elisa kit  >155 publications with CCR2 and CXCL12
 CCL7 elisa kit  >92 publications with CCR2 and CCL7
 CCL8 elisa kit  >48 publications with CCR2 and CCL8
 CCL11 elisa kit  >46 publications with CCR2 and CCL11
 CCL13 elisa kit  >27 publications with CCR2 and CCL13
 CCL22 elisa kit  >15 publications with CCR2 and CCL22
 CCL16 elisa kit  >7 publications with CCR2 and CCL16
 JAK2 elisa kit  >5 publications with CCR2 and JAK2
 Products by Pathway  Pathway Diagram
 Beta Defensins Pathway antibodies  Beta Defensins Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Defensins Pathway antibodies  Defensins Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
Diseases associated with CCR2 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >813 publications with CCR2 and Inflammation
 Immune System Diseases Antibodies  >526 publications with CCR2 and Immune System Diseases
 Disease Models, Animal Antibodies  >359 publications with CCR2 and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >333 publications with CCR2 and Cardiovascular Diseases
 Nervous System Diseases Antibodies  >291 publications with CCR2 and Nervous System Diseases
 Necrosis Antibodies  >238 publications with CCR2 and Necrosis
 Atherosclerosis Antibodies  >199 publications with CCR2 and Atherosclerosis
 Lung Diseases Antibodies  >167 publications with CCR2 and Lung Diseases
 Fibrosis Antibodies  >115 publications with CCR2 and Fibrosis
 Kidney Diseases Antibodies  >106 publications with CCR2 and Kidney Diseases
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