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CXCL17 elisa kit :: Human chemokine (C X C motif) ligand 17 (CXCL17) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7239012
Typical Standard Curve/Testing Data
Unit / Price
48-Strip-Wells  /  $455 +1 FREE 8GB USB
96-Strip-Wells  /  $660 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

chemokine (C X C motif) ligand 17 (CXCL17), ELISA Kit

★Popular Item★
 Also Known As   

Human chemokine (C X C motif) ligand 17 (CXCL17) ELISA Kit

 Product Gene Name   

CXCL17 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    601393
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of CXCL-17. No significant cross-reactivity or interference between CXCL-17 and analogues was observed. NOTE: Limited by current skills and knowledge, it is impossible for us to complete the cross-reactivity detection between CXCL-17 and all the analogues, therefore, cross reaction may still exist in some cases.
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
 Assay Type    Competitive
 Detection Range    250-5000 pg/mL
 Sensitivity    1.0pg/mL
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CXCL17 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CXCL17 purchase    MBS7239012 is a ready-to-use microwell, strip plate Competitive ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the chemokine (C X C motif) ligand 17 (CXCL17) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 250-5000 pg/mL in biological research samples containing CXCL17, with an estimated sensitivity of 1.0pg/mL. The ELISA analytical biochemical technique of the MBS7239012 kit is based on CXCL17 antibody-CXCL17 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CXCL17 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CXCL17. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for CXCL17 elisa kit

   Intended Uses: This CXCL-17 ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Human CXCL-17. This ELISA kit for research use only, not for therapeutic or diagnostic applications!

Principle of the Assay: CXCL-17 ELISA kit applies the competitive enzyme immunoassay technique utilizing a polyclonal anti-CXCL-17 antibody and an CXCL-17-HRP conjugate. The assay sample and buffer are incubated together with CXCL-17-HRP conjugate in pre-coated plate for one hour. After the incubation period, the wells are decanted and washed five times. The wells are then incubated with a substrate for HRP enzyme. The product of the enzyme-substrate reaction forms a blue colored complex. Finally, a stop solution is added to stop the reaction, which will then turn the solution yellow. The intensity of color is measured spectrophotometrically at 450nm in a microplate reader. The intensity of the color is inversely proportional to the CXCL-17 concentration since CXCL-17 from samples and CXCL-17-HRP conjugate compete for the anti-CXCL-17 antibody binding site. Since the number of sites is limited, as more sites are occupied by CXCL-17 from the sample, fewer sites are left to bind CXCL-17-HRP conjugate. A standard curve is plotted relating the intensity of the color (O.D.) to the concentration of standards. The CXCL-17 concentration in each sample is interpolated from this standard curve.
 Product Categories/Family for CXCL17 elisa kit    Immunology
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 Typical Standard Curve/Testing Data of CXCL17 elisa kit    CXCL17 elisa kit Typical Standard Curve/Testing Data image
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Sample Manual Insert of MBS7239012. Click to request current manual
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NCBI/Uniprot data below describe general gene information for CXCL17. It may not necessarily be applicable to this product.
 NCBI GI #    4204910
 NCBI GeneID    6359
 NCBI Accession #    AAD10847.1 [Other Products]
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 UniProt Secondary Accession #    Q9UM74; B2RU34; E1P651 [Other Products]
 UniProt Related Accession #    Q16663 [Other Products]
 Molecular Weight    12,248 Da
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 NCBI Official Full Name    chemokine
 NCBI Official Synonym Full Names    chemokine (C-C motif) ligand 15
 NCBI Official Symbol    CCL15 [Similar Products]
 NCBI Official Synonym Symbols   
LKN1; NCC3; SY15; HCC-2; LKN-1; MIP-5; NCC-3; SCYL3; MIP-1D; MRP-2B; SCYA15; HMRP-2B; MIP-1 delta
[Similar Products]
 NCBI Protein Information    C-C motif chemokine 15; leukotactin 1; chemokine CC-2; new CC chemokine 3; small-inducible cytokine A15; macrophage inflammatory protein 5; small inducible cytokine subfamily A (Cys-Cys), member 15
 UniProt Protein Name    C-C motif chemokine 15
 UniProt Synonym Protein Names   
Chemokine CC-2; HCC-2; Leukotactin-1; LKN-1; MIP-1 delta; Macrophage inflammatory protein 5; MIP-5; Mrp-2b; NCC-3; Small-inducible cytokine A15Cleaved into the following 3 chains:CCL15(22-92); CCL15(25-92); CCL15(29-92)
 Protein Family    VEGF coregulated chemokine
 UniProt Gene Name    CCL15 [Similar Products]
 UniProt Synonym Gene Names    MIP5; NCC3; SCYA15; HCC-2; LKN-1; MIP-5 [Similar Products]
 UniProt Entry Name    CCL15_HUMAN
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 NCBI Summary for CXCL17    This gene is located in a cluster of similar genes in the same region of chromosome 17. These genes encode CC cytokines, which are secreted proteins characterized by two adjacent cysteines. The product of this gene is chemotactic for T cells and monocytes, and acts through C-C chemokine receptor type 1 (CCR1). The proprotein is further processed into numerous smaller functional peptides. Naturally-occurring readthrough transcripts occur from this gene into the downstream gene, CCL14 (chemokine (C-C motif) ligand 14). [provided by RefSeq, Jan 2013]
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 UniProt Comments for CXCL17    CCL15: Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the small-inducible cytokine A15. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: extracellular space

Molecular Function: heparin binding; chemokine activity; chemoattractant activity; receptor binding

Biological Process: cellular calcium ion homeostasis; cell-cell signaling; positive chemotaxis; immune response; signal transduction; chemotaxis
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 Research Articles on CXCL17    1. we investigated a role of CCL15 in upregulating ICAM-1 in endothelial cells
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CXCL17 elisa kitPathways associated with CXCL17 elisa kit
 Reference Product  PubMed Publications
 CCR1 elisa kit  >28 publications with CXCL17 and CCR1
 CCR3 elisa kit  >11 publications with CXCL17 and CCR3
 CCR2 elisa kit  >5 publications with CXCL17 and CCR2
 CCR5 elisa kit  >4 publications with CXCL17 and CCR5
 CCR6 elisa kit  >2 publications with CXCL17 and CCR6
 CCR8 elisa kit  >1 publications with CXCL17 and CCR8
 CCR7 elisa kit  >1 publications with CXCL17 and CCR7
 Products by Pathway  Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
Diseases associated with CXCL17 elisa kitOrgans/Tissues associated with CXCL17 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >21 publications with CXCL17 and Inflammation
 Carcinoma Antibodies  >6 publications with CXCL17 and Carcinoma
 Necrosis Antibodies  >6 publications with CXCL17 and Necrosis
 Liver Neoplasms Antibodies  >5 publications with CXCL17 and Liver Neoplasms
 Liver Diseases Antibodies  >5 publications with CXCL17 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >4 publications with CXCL17 and Carcinoma, Hepatocellular
 Kidney Diseases Antibodies  >3 publications with CXCL17 and Kidney Diseases
 Adenocarcinoma Antibodies  >3 publications with CXCL17 and Adenocarcinoma
 Neoplasm Metastasis Antibodies  >3 publications with CXCL17 and Neoplasm Metastasis
 Atherosclerosis Antibodies  >2 publications with CXCL17 and Atherosclerosis
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >8 publications with CXCL17 and Liver
 Lung Antibodies  >5 publications with CXCL17 and Lung
 Kidney Antibodies  >4 publications with CXCL17 and Kidney
 Intestine Antibodies  >3 publications with CXCL17 and Intestine
 Brain Antibodies  >2 publications with CXCL17 and Brain
 Ascites Antibodies  >1 publications with CXCL17 and Ascites
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