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CBY1 elisa kit :: Human chibby homolog 1 (Drosophila) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9319849 CBY1 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

chibby homolog 1 (Drosophila) (CBY1), ELISA Kit

 Also Known As   

Human Protein chibby homolog 1, CBY1 ELISA Kit

 Product Synonym Names    Human Protein chibby homolog 1 (CBY1) ELISA kit; RP3-508I15.8; C22orf2; CBY; HS508I15A; PGEA1; PIGEA-14; PIGEA14; arb1; ARPP-binding protein; OTTHUMP00000198876; PKD2 interactor; golgi and endoplasmic reticulum associated 1; coiled-coil protein PIGEA; chibby homolog 1 (Drosophila)
 Product Gene Name   

CBY1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    607757
 3D Structure    ModBase 3D Structure for Q9Y3M2
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CBY1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CBY1 purchase    MBS9319849 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the chibby homolog 1 (Drosophila) (CBY1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CBY1. The ELISA analytical biochemical technique of the MBS9319849 kit is based on CBY1 antibody-CBY1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CBY1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CBY1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for CBY1. It may not necessarily be applicable to this product.
 NCBI GI #    389886564
 NCBI GeneID    25776
 NCBI Accession #    NP_001002880.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001002880.1 [Other Products]
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 UniProt Primary Accession #    Q9Y3M2 [Other Products]
 UniProt Secondary Accession #    Q66GT6; Q9UIK9; B2R4S2 [Other Products]
 UniProt Related Accession #    Q9Y3M2 [Other Products]
 Molecular Weight    14,470 Da
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 NCBI Official Full Name    protein chibby homolog 1 isoform b
 NCBI Official Synonym Full Names    chibby homolog 1 (Drosophila)
 NCBI Official Symbol    CBY1 [Similar Products]
 NCBI Official Synonym Symbols   
CBY; arb1; PGEA1; C22orf2; PIGEA14; PIGEA-14; HS508I15A
[Similar Products]
 NCBI Protein Information    protein chibby homolog 1; ARPP-binding protein; coiled-coil protein PIGEA-14; cytosolic leucine-rich protein; chibby CTNNB1-mediated transcription inhibitor; PKD2 interactor, Golgi and endoplasmic reticulum-associated 1; PKD2 interactor, golgi and endoplasmic reticulum associated 1; polycystin-2 interactor, Golgi- and endoplasmic reticulum-associated protein, 14 kDa
 UniProt Protein Name    Protein chibby homolog 1
 UniProt Synonym Protein Names   
ARPP-binding protein; Cytosolic leucine-rich protein; PIGEA-14; PKD2 interactor, Golgi and endoplasmic reticulum-associated 1
 Protein Family    Protein chibby
 UniProt Gene Name    CBY1 [Similar Products]
 UniProt Synonym Gene Names    ARB1; C22orf2; CBY; PGEA1; HRIHFB2025 [Similar Products]
 UniProt Entry Name    CBY1_HUMAN
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 NCBI Summary for CBY1    Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CBY1    CBY1: Inhibits the Wnt/Wingless pathway by binding to beta- catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation. Belongs to the chibby family.

Protein type: Transcription regulation

Chromosomal Location of Human Ortholog: 22q12

Cellular Component: nucleoplasm; nuclear speck; trans-Golgi network; nucleus; cytosol

Molecular Function: identical protein binding; protein binding; beta-catenin binding

Biological Process: fat cell differentiation; protein localization; negative regulation of Wnt receptor signaling pathway; negative regulation of transcription, DNA-dependent; cardiac muscle cell differentiation
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 Research Articles on CBY1    1. Stable expression of CBY1 drives beta catenin cytoplasmatic translocation and impairs beta catenin signaling in BCR-ABL + cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CBY1 elisa kitPathways associated with CBY1 elisa kit
 Reference Product  PubMed Publications
 CTNNB1 elisa kit  >17 publications with CBY1 and CTNNB1
 Products by Pathway  Pathway Diagram
 Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway antibodies  Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway Diagram
Diseases associated with CBY1 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >11 publications with CBY1 and Neoplasms
 Kidney Diseases Antibodies  >3 publications with CBY1 and Kidney Diseases
 Breast Neoplasms Antibodies  >2 publications with CBY1 and Breast Neoplasms
 Breast Diseases Antibodies  >1 publications with CBY1 and Breast Diseases
 Nervous System Diseases Antibodies  >1 publications with CBY1 and Nervous System Diseases
 Lung Diseases Antibodies  >1 publications with CBY1 and Lung Diseases
 Adenocarcinoma Antibodies  >1 publications with CBY1 and Adenocarcinoma
 Lung Neoplasms Antibodies  >1 publications with CBY1 and Lung Neoplasms
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