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C10orf59 elisa kit :: Human chromosome 10 open reading frame 59 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS703138
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $550 +1 FREE 8GB USB
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 Product Name   

chromosome 10 open reading frame 59 (C10orf59), ELISA Kit

★Popular Item★
 Also Known As   

Human Renalase/ Monoamine Oxidase-C, RNLS/ MAO-C ELISA Kit

 Product Synonym Names    Human Renalase/ Monoamine Oxidase-C (RNLS/ MAO-C) ELISA Kit; C10orf59; FLJ11218; RENALASE; renalase; chromosome 10 open reading frame 59
 Product Gene Name   

C10orf59 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS703138 Testing Data    Testing Data PDF
 OMIM    609360
 3D Structure    ModBase 3D Structure for Q5VYX0
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human C10orf59. No significant cross-reactivity or interference between Human C10orf59 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates
 Assay Type    Sandwich
 Detection Range    0.625 ug/ml-40 ug/ml
 Sensitivity    0.156 ug/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of C10orf59 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for C10orf59 purchase    MBS703138 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the chromosome 10 open reading frame 59 (C10orf59) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.625 ug/ml-40 ug/ml in biological research samples containing C10orf59, with an estimated sensitivity of 0.156 ug/ml. The ELISA analytical biochemical technique of the MBS703138 kit is based on C10orf59 antibody-C10orf59 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect C10orf59 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, C10orf59. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for C10orf59 elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for RNLS has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any RNLS present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for RNLS is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of RNLS bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of C10orf59 elisa kit    C10orf59 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS703138. Click to request current manual
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NCBI/Uniprot data below describe general gene information for C10orf59. It may not necessarily be applicable to this product.
 NCBI GI #    237649117
 NCBI GeneID    55328
 NCBI Accession #    NP_001026879.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001031709.2 [Other Products]
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 UniProt Primary Accession #    Q5VYX0 [Other Products]
 UniProt Secondary Accession #    Q9BS33; Q9NUP8 [Other Products]
 UniProt Related Accession #    Q5VYX0 [Other Products]
 Molecular Weight    37,847 Da
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 NCBI Official Full Name    renalase isoform 1
 NCBI Official Synonym Full Names    renalase, FAD-dependent amine oxidase
 NCBI Official Symbol    RNLS [Similar Products]
 NCBI Official Synonym Symbols   
C10orf59; RENALASE
[Similar Products]
 NCBI Protein Information    renalase; MAO-C; monoamine oxidase-C; alpha-NAD(P)H oxidase/anomerase
 UniProt Protein Name    Renalase
 UniProt Synonym Protein Names   
Monoamine oxidase-C; MAO-C; alpha-NAD(P)H oxidase/anomerase
 UniProt Gene Name    RNLS [Similar Products]
 UniProt Synonym Gene Names    C10orf59; MAO-C [Similar Products]
 UniProt Entry Name    RNLS_HUMAN
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 NCBI Summary for C10orf59    Renalase is a flavin adenine dinucleotide-dependent amine oxidase that is secreted into the blood from the kidney (Xu et al., 2005 [PubMed 15841207]).[supplied by OMIM, Mar 2008]
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 UniProt Comments for C10orf59    Function: Catalyzes the oxidation of the less abundant alpha-NAD(P)H isoform to form beta-NAD(P)+. The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.2 PublicationsManual assertion based on experiment in:Ref.4

Catalytic activity: Alpha-NAD(P)H + O2 = beta-NAD(P)+ + H2O2.1 PublicationManual assertion based on experiment in:Ref.6

Cofactor: FAD.1 PublicationManual assertion based on experiment in:Ref.7
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 Research Articles on C10orf59    1. Renalase promotes cell survival and protects against renal injury through the activation of intracellular signaling cascades, independent of its ability to metabolize catecholamines.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with C10orf59 elisa kitPathways associated with C10orf59 elisa kit
 Reference Product  PubMed Publications
 FLNA elisa kit  >12 publications with C10orf59 and FLNA
 Products by Pathway  Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
Diseases associated with C10orf59 elisa kitOrgans/Tissues associated with C10orf59 elisa kit
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >2 publications with C10orf59 and Breast Neoplasms
 Neoplasm Metastasis Antibodies  >2 publications with C10orf59 and Neoplasm Metastasis
 Inflammation Antibodies  >2 publications with C10orf59 and Inflammation
 Hypertension Antibodies  >1 publications with C10orf59 and Hypertension
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >1 publications with C10orf59 and Eye
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