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CARS elisa kit :: Human cysteinyl-tRNA synthetase ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9329806 CARS elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

cysteinyl-tRNA synthetase (CARS), ELISA Kit

★Popular Item★
 Also Known As   

Human Cysteinyl-tRNA synthetase, cytoplasmic, CARS ELISA Kit

 Product Synonym Names    Human Cysteinyl-tRNA synthetase; cytoplasmic (CARS) ELISA kit; CARS1; CYSRS; MGC:11246; cysteine tRNA ligase 1; cytoplasmic; cysteine translase; cysteine-tRNA ligase; cysteinyl-tRNA synthetase
 Product Gene Name   

CARS elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    123859
 3D Structure    ModBase 3D Structure for P49589
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 Species Reactivity    Human
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Assay Type    Quantitative Sandwich
 Detection Range    3.12 ng/ml - 100 ng/ml
 Sensitivity    1.0 ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CARS elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CARS purchase    MBS9329806 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the cysteinyl-tRNA synthetase (CARS) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 3.12 ng/ml - 100 ng/ml in biological research samples containing CARS, with an estimated sensitivity of 1.0 ng/ml. The ELISA analytical biochemical technique of the MBS9329806 kit is based on CARS antibody-CARS antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CARS antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CARS. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for CARS elisa kit

   Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CARS (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9329806. Click to request current manual
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NCBI/Uniprot data below describe general gene information for CARS. It may not necessarily be applicable to this product.
 NCBI GI #    62240992
 NCBI GeneID    833
 NCBI Accession #    NP_001014437.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001014437.2 [Other Products]
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 UniProt Primary Accession #    P49589 [Other Products]
 UniProt Secondary Accession #    Q53XI8; Q5HYE4; Q9HD24; Q9HD25 [Other Products]
 UniProt Related Accession #    P49589 [Other Products]
 Molecular Weight    85,473 Da
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 NCBI Official Full Name    cysteine--tRNA ligase, cytoplasmic isoform c
 NCBI Official Synonym Full Names    cysteinyl-tRNA synthetase
 NCBI Official Symbol    CARS [Similar Products]
 NCBI Official Synonym Symbols   
CARS1; CYSRS; MGC:11246
[Similar Products]
 NCBI Protein Information    cysteine--tRNA ligase, cytoplasmic; cysteine translase; cysteine tRNA ligase 1, cytoplasmic
 UniProt Protein Name    Cysteine--tRNA ligase, cytoplasmic
 UniProt Synonym Protein Names   
Cysteinyl-tRNA synthetase; CysRS
 Protein Family    CDP-archaeol synthase
 UniProt Gene Name    CARS [Similar Products]
 UniProt Synonym Gene Names    CysRS [Similar Products]
 UniProt Entry Name    SYCC_HUMAN
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 NCBI Summary for CARS    This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2010]
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 UniProt Comments for CARS    CARS: a class 1 aminoacyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. Two alternatively spliced isoforms are described.

Protein type: Translation; Oncoprotein; Ligase; EC 6.1.1.16

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: cytoplasm; cytosol

Molecular Function: protein binding; protein homodimerization activity; cysteine-tRNA ligase activity; metal ion binding; ATP binding; tRNA binding

Biological Process: tRNA aminoacylation for protein translation; cysteinyl-tRNA aminoacylation; gene expression
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 Research Articles on CARS    1. Observational study of gene-disease association. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with CARS elisa kitDiseases associated with CARS elisa kit
 Products by Pathway  Pathway Diagram
 Aminoacyl-tRNA Biosynthesis Pathway antibodies  Aminoacyl-tRNA Biosynthesis Pathway Diagram
 Aminoacyl-tRNA Biosynthesis Pathway antibodies  Aminoacyl-tRNA Biosynthesis Pathway Diagram
 Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway antibodies  Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway Diagram
 Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway antibodies  Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway Diagram
 Cytosolic TRNA Aminoacylation Pathway antibodies  Cytosolic TRNA Aminoacylation Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 TRNA Aminoacylation Pathway antibodies  TRNA Aminoacylation Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >578 publications with CARS and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >228 publications with CARS and Cardiovascular Diseases
 Neoplasms Antibodies  >206 publications with CARS and Neoplasms
 Vascular Diseases Antibodies  >158 publications with CARS and Vascular Diseases
 Heart Diseases Antibodies  >109 publications with CARS and Heart Diseases
 Pain Antibodies  >107 publications with CARS and Pain
 Inflammation Antibodies  >67 publications with CARS and Inflammation
 Drug Toxicity Antibodies  >62 publications with CARS and Drug Toxicity
 Fatigue Antibodies  >56 publications with CARS and Fatigue
 Hypertension Antibodies  >56 publications with CARS and Hypertension
Organs/Tissues associated with CARS elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >481 publications with CARS and Blood
 Brain Antibodies  >255 publications with CARS and Brain
 Bone Antibodies  >230 publications with CARS and Bone
 Lung Antibodies  >172 publications with CARS and Lung
 Eye Antibodies  >157 publications with CARS and Eye
 Skin Antibodies  >146 publications with CARS and Skin
 Heart Antibodies  >142 publications with CARS and Heart
 Muscle Antibodies  >107 publications with CARS and Muscle
 Liver Antibodies  >78 publications with CARS and Liver
 Kidney Antibodies  >72 publications with CARS and Kidney
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