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CYP4A11 elisa kit :: Human cytochrome P450, family 4, subfamily A, polypeptide 11 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS937597
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (Limit 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

cytochrome P450, family 4, subfamily A, polypeptide 11 (CYP4A11), ELISA Kit

 Also Known As   

Human Cytochrome P450 4A11, CYP4A11 ELISA Kit

 Product Synonym Names    Human Cytochrome P450 4A11 (CYP4A11) ELISA kit; CP4Y; CYP4A2; CYP4AII; P450HL-omega; alkane-1 monooxygenase; cytochrome P450; subfamily IVA; polypeptide 11; fatty acid omega-hydroxylase; lauric acid omega-hydroxylase; cytochrome P450; family 4; subfamily A; polypeptide 11
 Product Gene Name   

CYP4A11 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 MBS937597 Testing Data    Testing Data PDF
 OMIM    601310
 3D Structure    ModBase 3D Structure for Q02928
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human CYP4A11. No significant cross-reactivity or interference between Human CYP4A11 and analogues was observed.
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 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CYP4A11 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CYP4A11 purchase    MBS937597 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the cytochrome P450, family 4, subfamily A, polypeptide 11 (CYP4A11) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CYP4A11. The ELISA analytical biochemical technique of the MBS937597 kit is based on CYP4A11 antibody-CYP4A11 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CYP4A11 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CYP4A11. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Typical Testing Data/Standard Curve (for reference only) of CYP4A11 elisa kit    CYP4A11 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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NCBI/Uniprot data below describe general gene information for CYP4A11. It may not necessarily be applicable to this product.
 NCBI GI #    158937242
 NCBI GeneID    1579
 NCBI Accession #    NP_000769.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000778.3 [Other Products]
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 UniProt Primary Accession #    Q02928 [Other Products]
 UniProt Secondary Accession #    Q06766; Q16865; Q16866; Q5VSP8; Q86SU6; Q8IWY5 [Other Products]
 UniProt Related Accession #    Q02928 [Other Products]
 Molecular Weight    59,348 Da
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 NCBI Official Full Name    cytochrome P450 4A11
 NCBI Official Synonym Full Names    cytochrome P450, family 4, subfamily A, polypeptide 11
 NCBI Official Symbol    CYP4A11 [Similar Products]
 NCBI Official Synonym Symbols   
CP4Y; CYP4A2; CYP4AII
[Similar Products]
 NCBI Protein Information    cytochrome P450 4A11; CYPIVA11; P450HL-omega; 20-HETE synthase; alkane-1 monooxygenase; cytochrome P450HL-omega; cytochrome P-450HK-omega; fatty acid omega-hydroxylase; lauric acid omega-hydroxylase; 20-hydroxyeicosatetraenoic acid synthase; cytochrome P450, subfamily IVA, polypeptide 11
 UniProt Protein Name    Cytochrome P450 4A11
 UniProt Synonym Protein Names   
20-hydroxyeicosatetraenoic acid synthase; 20-HETE synthase; CYP4AII; CYPIVA11; Cytochrome P-450HK-omega; Cytochrome P450HL-omega; Fatty acid omega-hydroxylase; Lauric acid omega-hydroxylase (EC:1.14.15.3)
 Protein Family    Cytochrome
 UniProt Gene Name    CYP4A11 [Similar Products]
 UniProt Synonym Gene Names    CYP4A2; 20-HETE synthase [Similar Products]
 UniProt Entry Name    CP4AB_HUMAN
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 NCBI Summary for CYP4A11    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CYP4A11    CYP4A11: Catalyzes the omega- and (omega-1)-hydroxylation of various fatty acids such as laurate, myristate and palmitate. Has little activity toward prostaglandins A1 and E1. Oxidizes arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE). Belongs to the cytochrome P450 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.14.15.3; Lipid Metabolism - fatty acid; Cofactor and Vitamin Metabolism - retinol; Oxidoreductase; Lipid Metabolism - arachidonic acid; Endoplasmic reticulum

Chromosomal Location of Human Ortholog: 1p33

Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle; cytoplasm; apical plasma membrane

Molecular Function: leukotriene-B4 20-monooxygenase activity; iron ion binding; heme binding; arachidonic acid epoxygenase activity; alkane 1-monooxygenase activity

Biological Process: xenobiotic metabolic process; positive regulation of icosanoid secretion; renal water homeostasis; arachidonic acid metabolic process; leukotriene metabolic process; sodium ion homeostasis; epoxygenase P450 pathway; long-chain fatty acid metabolic process; cellular lipid metabolic process; fatty acid metabolic process; pressure natriuresis
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 Research Articles on CYP4A11    1. This meta-analysis revealed that the RGS2 1891-1892del TC polymorphism and CYP4A11 T8590C polymorphism were associated with hypertension risk.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with CYP4A11 elisa kitDiseases associated with CYP4A11 elisa kit
 Products by Pathway  Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Cytochrome P450 - Arranged By Substrate Type Pathway antibodies  Cytochrome P450 - Arranged By Substrate Type Pathway Diagram
 Fatty Acid Omega Oxidation Pathway antibodies  Fatty Acid Omega Oxidation Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Fatty Acids Pathway antibodies  Fatty Acids Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >16 publications with CYP4A11 and Fatty Liver
 Liver Diseases Antibodies  >7 publications with CYP4A11 and Liver Diseases
 Drug Toxicity Antibodies  >6 publications with CYP4A11 and Drug Toxicity
 Neoplasms Antibodies  >5 publications with CYP4A11 and Neoplasms
 Brain Diseases Antibodies  >5 publications with CYP4A11 and Brain Diseases
 Inflammation Antibodies  >4 publications with CYP4A11 and Inflammation
 Carcinoma, Hepatocellular Antibodies  >2 publications with CYP4A11 and Carcinoma, Hepatocellular
 Cerebral Hemorrhage Antibodies  >2 publications with CYP4A11 and Cerebral Hemorrhage
 Myocardial Infarction Antibodies  >2 publications with CYP4A11 and Myocardial Infarction
 Lung Diseases Antibodies  >2 publications with CYP4A11 and Lung Diseases
Organs/Tissues associated with CYP4A11 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >45 publications with CYP4A11 and Liver
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