NP_005785.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
29,927 Da
NCBI Official Full Name
dehydrogenase/reductase SDR family member 2, mitochondrial isoform 2
NCBI Official Synonym Full Names
dehydrogenase/reductase (SDR family) member 2
NCBI Protein Information
dehydrogenase/reductase SDR family member 2, mitochondrial; protein D; dicarbonyl reductase HEP27; dehydrogenase/reductase member 2; short-chain alcohol dehydrogenase family member; short chain dehydrogenase/reductase family 25C, member 1
UniProt Protein Name
Dehydrogenase/reductase SDR family member 2, mitochondrial
UniProt Synonym Protein Names
Dicarbonyl reductase HEP27; Protein D
UniProt Entry Name
DHRS2_HUMAN
UniProt Comments for DHRS2
DHRS2: Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2- propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. May inhibit cell replication. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Oxidoreductase; EC 1.1.1.-; EC 1.1.-.-
Chromosomal Location of Human Ortholog: 14q11.2
Cellular Component: mitochondrion; mitochondrial matrix; cytoplasm; nuclear envelope; nucleus
Molecular Function: carbonyl reductase (NADPH) activity
Biological Process: negative regulation of cell proliferation; response to toxin; C21-steroid hormone metabolic process; myeloid dendritic cell differentiation; negative regulation of apoptosis
Research Articles on DHRS2
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Diseases associated with DHRS2 elisa kit
Organs/Tissues associated with DHRS2 elisa kit
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