NP_112289.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
111,468 Da
NCBI Official Full Name
dihydropyrimidine dehydrogenase
NCBI Official Synonym Full Names
dihydropyrimidine dehydrogenase
NCBI Protein Information
dihydropyrimidine dehydrogenase [NADP(+)]; dihydropyrimidine dehydrogenase [NADP(+)]; DPD; DHPDHase; dihydrouracil dehydrogenase; dihydrothymine dehydrogenase
UniProt Protein Name
Dihydropyrimidine dehydrogenase [NADP(+)]
UniProt Synonym Protein Names
Dihydrothymine dehydrogenase; Dihydrouracil dehydrogenase
UniProt Synonym Gene Names
UniProt Entry Name
DPYD_RAT
NCBI Summary for DPD
catalyzes the conversion of 5,6-dihydrouracil and NADP+ to uracil, NADPH, and H+ in pyrimidine degradation [RGD, Feb 2006]
UniProt Comments for DPD
Function: Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine
Catalytic activity: 5,6-dihydrouracil + NADP+ = uracil + NADPH.
Cofactor: Binds 4 4Fe-4S clusters. Contains approximately 16 iron atoms per subunit
Enzyme regulation: Inactivated by 5-iodouracil
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Products associated with DPD elisa kit
Pathways associated with DPD elisa kit
Diseases associated with DPD elisa kit
Organs/Tissues associated with DPD elisa kit
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