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DAGLA elisa kit :: Human diacylglycerol lipase, alpha ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9322678 DAGLA elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

diacylglycerol lipase, alpha (DAGLA), ELISA Kit

 Also Known As   

Human Sn1-specific diacylglycerol lipase alpha, DAGLA ELISA Kit

 Product Synonym Names    Human Sn1-specific diacylglycerol lipase alpha (DAGLA) ELISA kit; C11orf11; DAGL (ALPHA); DAGLALPHA; NSDDR; neural stem cell-derived dendrite regulator; diacylglycerol lipase; alpha
 Product Gene Name   

DAGLA elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    614015
 3D Structure    ModBase 3D Structure for Q9Y4D2
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 Species Reactivity    Human
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
 Assay Type    Sandwich
 Detection Range    0.625ng/ml-20ng/ml.
 Sensitivity    0.1ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of DAGLA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for DAGLA purchase    MBS9322678 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the diacylglycerol lipase, alpha (DAGLA) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.625ng/ml-20ng/ml in biological research samples containing DAGLA, with an estimated sensitivity of 0.1ng/ml. The ELISA analytical biochemical technique of the MBS9322678 kit is based on DAGLA antibody-DAGLA antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect DAGLA antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, DAGLA. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for DAGLA elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of DAGLA (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9322678. Click to request current manual
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NCBI/Uniprot data below describe general gene information for DAGLA. It may not necessarily be applicable to this product.
 NCBI GI #    27262632
 NCBI GeneID    747
 NCBI Accession #    NP_006124.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006133.2 [Other Products]
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 UniProt Primary Accession #    Q9Y4D2 [Other Products]
 UniProt Secondary Accession #    Q6WQJ0; A7E233 [Other Products]
 UniProt Related Accession #    Q9Y4D2 [Other Products]
 Molecular Weight    114,952 Da
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 NCBI Official Full Name    sn1-specific diacylglycerol lipase alpha
 NCBI Official Synonym Full Names    diacylglycerol lipase, alpha
 NCBI Official Symbol    DAGLA [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    sn1-specific diacylglycerol lipase alpha; DGL-alpha; neural stem cell-derived dendrite regulator
 UniProt Protein Name    Sn1-specific diacylglycerol lipase alpha
 UniProt Synonym Protein Names   
Neural stem cell-derived dendrite regulator
 Protein Family    Sn1-specific diacylglycerol lipase
 UniProt Gene Name    DAGLA [Similar Products]
 UniProt Synonym Gene Names    C11orf11; KIAA0659; NSDDR; DGL-alpha [Similar Products]
 UniProt Entry Name    DGLA_HUMAN
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 NCBI Summary for DAGLA    This gene encodes a diacylglycerol lipase. The encoded enzyme is involved in the biosynthesis of the endocannabinoid 2-arachidonoyl-glycerol.[provided by RefSeq, Nov 2010]
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 UniProt Comments for DAGLA    NSDDR: Catalyzes the hydrolysis of diacylglycerol (DAG) to 2- arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. Required for axonal growth during development and for retrograde synaptic signaling at mature synapses. Defects in DAGLA may be a cause of spinocerebellar ataxia type 20 (SCA20). Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCA20 is an autosomal dominant, adult- onset form characterized by dysarthria due to spasmodic dysphonia followed by slowly progressive ataxia. A copy number variation consisting of a 260-kb duplication at chromosome 11q12.2-12.3 is responsible for SCA20. The critical gene within the duplicated segment may be DAGLA. Belongs to the AB hydrolase superfamily. Lipase family.

Protein type: Membrane protein, integral; Hydrolase; EC 3.1.1.-; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 11q12.2

Cellular Component: integral to membrane; plasma membrane

Molecular Function: metal ion binding; lipase activity

Biological Process: platelet activation; neuroblast proliferation; diacylglycerol catabolic process; arachidonic acid metabolic process; blood coagulation; neurotransmitter biosynthetic process
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 Research Articles on DAGLA    1. DAGLalpha mRNA expression is lowest in early life and adulthood, peaking between school age and young adulthood.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with DAGLA elisa kitDiseases associated with DAGLA elisa kit
 Products by Pathway  Pathway Diagram
 Arachidonate Production From DAG Pathway antibodies  Arachidonate Production From DAG Pathway Diagram
 Effects Of PIP2 Hydrolysis Pathway antibodies  Effects Of PIP2 Hydrolysis Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 N-cadherin Signaling Events Pathway antibodies  N-cadherin Signaling Events Pathway Diagram
 Platelet Activation, Signaling And Aggregation Pathway antibodies  Platelet Activation, Signaling And Aggregation Pathway Diagram
 Retrograde Endocannabinoid Signaling Pathway antibodies  Retrograde Endocannabinoid Signaling Pathway Diagram
 Retrograde Endocannabinoid Signaling Pathway antibodies  Retrograde Endocannabinoid Signaling Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Disease Name  Pubmed Publications
 Kidney disorder involving deposition of calcium and oxalate or phosphate in the renal tubules Antibodies  >2463 publications with DAGLA and Kidney disorder involving deposition of calcium and oxalate or phosphate in the renal tubules
 Brain Diseases Antibodies  >1 publications with DAGLA and Brain Diseases
 Ataxia Antibodies  >1 publications with DAGLA and Ataxia
 Cerebellar Diseases Antibodies  >1 publications with DAGLA and Cerebellar Diseases
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