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DNAH5 elisa kit :: Human dynein, axonemal, heavy chain 5 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9337198 DNAH5 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

dynein, axonemal, heavy chain 5 (DNAH5), ELISA Kit

★Popular Item★
 Also Known As   

Human Dynein heavy chain 5, axonemal, DNAH5 ELISA Kit

 Product Synonym Names    Human Dynein heavy chain 5; axonemal (DNAH5) ELISA kit; CILD3; DNAHC5; FLJ46759; HL1; KIAA1603; KTGNR; PCD; axonemal beta dynein heavy chain 5; ciliary dynein heavy chain 5; dynein; axonemal; heavy polypeptide 5; dynein; axonemal; heavy chain 5
 Product Gene Name   

DNAH5 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    gene 608644
 3D Structure    ModBase 3D Structure for Q8TE73
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 Species Reactivity    Human
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Body fluids, tissue homogenates, secretions or feces samples
 Assay Type    Quantitative Sandwich
 Detection Range    3.12 ng/ml - 100 ng/ml
 Sensitivity    1.0 ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of DNAH5 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for DNAH5 purchase    MBS9337198 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the dynein, axonemal, heavy chain 5 (DNAH5) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 3.12 ng/ml - 100 ng/ml in biological research samples containing DNAH5, with an estimated sensitivity of 1.0 ng/ml. The ELISA analytical biochemical technique of the MBS9337198 kit is based on DNAH5 antibody-DNAH5 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect DNAH5 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, DNAH5. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Body fluids, tissue homogenates, secretions or feces samples. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for DNAH5 elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of DNAH5 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9337198. Click to request current manual
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NCBI/Uniprot data below describe general gene information for DNAH5. It may not necessarily be applicable to this product.
 NCBI GI #    19115954
 NCBI GeneID    1767
 NCBI Accession #    NP_001360.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001369.2 [Other Products]
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 UniProt Primary Accession #    Q8TE73 [Other Products]
 UniProt Secondary Accession #    Q92860; Q96L74; Q9H5S7; Q9HCG9 [Other Products]
 UniProt Related Accession #    Q8TE73 [Other Products]
 Molecular Weight    529,021 Da
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 NCBI Official Full Name    dynein heavy chain 5, axonemal
 NCBI Official Synonym Full Names    dynein, axonemal, heavy chain 5
 NCBI Official Symbol    DNAH5 [Similar Products]
 NCBI Official Synonym Symbols   
HL1; PCD; CILD3; KTGNR; DNAHC5
[Similar Products]
 NCBI Protein Information    dynein heavy chain 5, axonemal; ciliary dynein heavy chain 5; axonemal beta dynein heavy chain 5; dynein, axonemal, heavy polypeptide 5
 UniProt Protein Name    Dynein heavy chain 5, axonemal
 UniProt Synonym Protein Names   
Axonemal beta dynein heavy chain 5; Ciliary dynein heavy chain 5
 Protein Family    Dynein
 UniProt Gene Name    DNAH5 [Similar Products]
 UniProt Synonym Gene Names    DNAHC5; HL1; KIAA1603 [Similar Products]
 UniProt Entry Name    DYH5_HUMAN
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 NCBI Summary for DNAH5    This gene encodes a dynein protein, which is part of a microtubule-associated motor protein complex consisting of heavy, light, and intermediate chains. This protein is an axonemal heavy chain dynein. It functions as a force-generating protein with ATPase activity, whereby the release of ADP is thought to produce the force-producing power stroke. Mutations in this gene cause primary ciliary dyskinesia type 3, as well as Kartagener syndrome, which are both diseases due to ciliary defects. [provided by RefSeq, Oct 2009]
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 UniProt Comments for DNAH5    DNAH5: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of the cilia of ependymal cells lining the brain ventricles. Defects in DNAH5 are the cause of primary ciliary dyskinesia type 3 (CILD3). CILD3 is an autosomal recessive disorder characterized by axonemal abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit situs inversus, due to dysfunction of monocilia at the embryonic node and randomization of left-right body asymmetry. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome. Defects in DNAH5 are a cause of Kartagener syndrome (KTGS). KTGS is an autosomal recessive disorder characterized by the association of primary ciliary dyskinesia with situs inversus. Clinical features include recurrent respiratory infections, bronchiectasis, infertility, and lateral transposition of the viscera of the thorax and abdomen. The situs inversus is most often total, although it can be partial in some cases (isolated dextrocardia or isolated transposition of abdominal viscera). Belongs to the dynein heavy chain family.

Protein type: Motor; Microtubule-binding; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 5p15.2

Cellular Component: microtubule; axonemal dynein complex; axoneme

Molecular Function: ATPase activity; microtubule motor activity; ATP binding

Biological Process: metabolic process; lateral ventricle development

Disease: Ciliary Dyskinesia, Primary, 3
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 Research Articles on DNAH5    1. DNAH5 (rs2277046) is associated with single nucleotide polymorphisms in Korean patients, either non-segmental or segmental type.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with DNAH5 elisa kitOrgans/Tissues associated with DNAH5 elisa kit
 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >23 publications with DNAH5 and Heart Diseases
 Respiratory System Abnormalities Antibodies  >22 publications with DNAH5 and Respiratory System Abnormalities
 Primary ciliary dyskinesia, 3 Antibodies  >13 publications with DNAH5 and Primary ciliary dyskinesia, 3
 Nervous System Diseases Antibodies  >2 publications with DNAH5 and Nervous System Diseases
 Neoplasm Invasiveness Antibodies  >1 publications with DNAH5 and Neoplasm Invasiveness
 Dysostoses Antibodies  >1 publications with DNAH5 and Dysostoses
 Inflammation Antibodies  >1 publications with DNAH5 and Inflammation
 Carcinoma Antibodies  >1 publications with DNAH5 and Carcinoma
 Immune System Diseases Antibodies  >1 publications with DNAH5 and Immune System Diseases
 Fibrosis Antibodies  >1 publications with DNAH5 and Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >4 publications with DNAH5 and Lung
 Blood Antibodies  >2 publications with DNAH5 and Blood
 Brain Antibodies  >2 publications with DNAH5 and Brain
 Bone Antibodies  >1 publications with DNAH5 and Bone
 Vascular Antibodies  >1 publications with DNAH5 and Vascular
 Trachea Antibodies  >1 publications with DNAH5 and Trachea
 Testis Antibodies  >1 publications with DNAH5 and Testis
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