NP_001361.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
475,983 Da
NCBI Official Full Name
dynein heavy chain 6, axonemal
NCBI Official Synonym Full Names
dynein, axonemal, heavy chain 6
NCBI Protein Information
dynein heavy chain 6, axonemal; dynein heavy chain-like 1; ciliary dynein heavy chain 6; axonemal beta dynein heavy chain 6; dynein, axonemal, heavy polypeptide 6
UniProt Protein Name
Dynein heavy chain 6, axonemal
UniProt Synonym Protein Names
Axonemal beta dynein heavy chain 6; Ciliary dynein heavy chain 6
UniProt Synonym Gene Names
UniProt Entry Name
DYH6_HUMAN
NCBI Summary for DNAH6
Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. Two major classes of dyneins, axonemal and cytoplasmic, have been identified. DNAH6 is an axonemal dynein heavy chain (DHC) (Vaughan et al., 1996 [PubMed 8812413]).[supplied by OMIM, Mar 2008]
UniProt Comments for DNAH6
DNAH6: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Belongs to the dynein heavy chain family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 2p11.2
Cellular Component: microtubule; axonemal dynein complex
Molecular Function: ATPase activity; microtubule motor activity; ATP binding
Biological Process: metabolic process; ciliary or flagellar motility; microtubule-based movement
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Diseases associated with DNAH6 elisa kit
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