NP_001276087.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
72,621 Da
NCBI Official Full Name
EGF-like module-containing mucin-like hormone receptor-like 3 isoform 2
NCBI Official Synonym Full Names
egf-like module containing, mucin-like, hormone receptor-like 3
NCBI Protein Information
EGF-like module-containing mucin-like hormone receptor-like 3; EGF-like module receptor 3; egf-like module-containing mucin-like receptor 3
UniProt Protein Name
EGF-like module-containing mucin-like hormone receptor-like 3
UniProt Synonym Protein Names
EGF-like module receptor 3Cleaved into the following 2 chains:EGF-like module-containing mucin-like hormone receptor-like 3 subunit alpha; EGF-like module-containing mucin-like hormone receptor-like 3 subunit beta
UniProt Synonym Gene Names
UniProt Entry Name
EMR3_HUMAN
NCBI Summary for EMR3
This gene encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2014]
UniProt Comments for EMR3
EMR3: Receptor probably involved in myeloid interactions during immune and inflammatory responses. A ligand for the soluble form of this receptor is present at the surface of momocytes- derived macrophages and activated neutrophils. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: GPCR, family 2; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 19p13.1
Cellular Component: extracellular space; plasma membrane; integral to membrane
Molecular Function: G-protein coupled receptor activity; calcium ion binding
Biological Process: G-protein coupled receptor protein signaling pathway
Research Articles on EMR3
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Pathways associated with EMR3 elisa kit
Diseases associated with EMR3 elisa kit
Organs/Tissues associated with EMR3 elisa kit
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