NP_001020095.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
101,982 Da
NCBI Official Full Name
exocyst complex component 1 isoform 1
NCBI Official Synonym Full Names
exocyst complex component 1
NCBI Protein Information
exocyst complex component 1; SEC3-like 1; exocyst complex component Sec3
UniProt Protein Name
Exocyst complex component 1
UniProt Synonym Protein Names
Exocyst complex component Sec3
UniProt Synonym Gene Names
UniProt Entry Name
EXOC1_HUMAN
NCBI Summary for EXOC1
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
UniProt Comments for EXOC1
EXOC1: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC3 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 4q12
Cellular Component: membrane; plasma membrane; exocyst; cytosol
Molecular Function: protein binding
Biological Process: protein transport; exocytosis; cellular protein metabolic process; organelle organization and biogenesis
Research Articles on EXOC1
Precautions
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Pathways associated with EXOC1 elisa kit
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