NP_001013861.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
83,382 Da
NCBI Official Full Name
exocyst complex component 7 isoform 1
NCBI Official Synonym Full Names
exocyst complex component 7
NCBI Official Synonym Symbols
EX070; EXO70; EXOC1; 2-5-3p; Exo70p; YJL085W [Similar Products]
NCBI Protein Information
exocyst complex component 7; exocyst complex component Exo70
UniProt Protein Name
Exocyst complex component 7
UniProt Synonym Protein Names
Exocyst complex component Exo70
UniProt Synonym Gene Names
UniProt Entry Name
EXOC7_HUMAN
NCBI Summary for EXOC7
The protein encoded by this gene is a component of the exocyst complex. The exocyst complex plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. The encoded protein is required for assembly of the exocyst complex and docking of the complex to the plasma membrane. The encoded protein may also play a role in pre-mRNA splicing through interactions with pre-mRNA-processing factor 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Nov 2011]
UniProt Comments for EXOC7
EXOC7: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion. Belongs to the EXO70 family. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 17q25.1
Cellular Component: membrane; exocyst; plasma membrane; microtubule organizing center; cytosol
Molecular Function: protein binding
Biological Process: protein transport; cellular protein metabolic process; exocytosis; organelle organization and biogenesis
Research Articles on EXOC7
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Products associated with EXOC7 elisa kit
Pathways associated with EXOC7 elisa kit
Diseases associated with EXOC7 elisa kit
Organs/Tissues associated with EXOC7 elisa kit
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