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FBN1 elisa kit :: Human fibrillin 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS702524
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $550 +1 FREE 8GB USB
96-Strip-Wells  /  $795 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,890 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,465 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

fibrillin 1 (FBN1), ELISA Kit

 Also Known As   

Human Fibrillin-1, FBN1 ELISA Kit

 Product Synonym Names    Human Fibrillin-1 (FBN1) ELISA Kit; FBN; MASS; MFS1; OCTD; SGS; WMS; fibrillin 15; fibrillin 1
 Product Gene Name   

FBN1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS702524 Testing Data    Testing Data PDF
 OMIM    614185
 3D Structure    ModBase 3D Structure for P35555
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human FBN1. No significant cross-reactivity or interference between Human FBN1 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates
 Detection Range    78 pg/ml-5000 pg/ml
 Sensitivity    19.5 pg/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of FBN1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for FBN1 purchase    MBS702524 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the fibrillin 1 (FBN1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 78 pg/ml-5000 pg/ml in biological research samples containing FBN1, with an estimated sensitivity of 19.5 pg/ml. The ELISA analytical biochemical technique of the MBS702524 kit is based on FBN1 antibody-FBN1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FBN1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FBN1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for FBN1 elisa kit

   Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to FBN1. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for FBN1 and Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB (3,3',5,5' tetramethyl-benzidine) substrate solution is added to each well. Only those wells that contain FBN1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of FBN1 in the samples is then determined by comparing the O.D. of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of FBN1 elisa kit    FBN1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS702524. Click to request current manual
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NCBI/Uniprot data below describe general gene information for FBN1. It may not necessarily be applicable to this product.
 NCBI GI #    281485550
 NCBI GeneID    2200
 NCBI Accession #    NP_000129.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_000138.4 [Other Products]
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 UniProt Primary Accession #    P35555 [Other Products]
 UniProt Secondary Accession #    Q15972; Q75N87; B2RUU0; D2JYH6 [Other Products]
 UniProt Related Accession #    P35555 [Other Products]
 Molecular Weight    312,237 Da
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 NCBI Official Full Name    fibrillin-1
 NCBI Official Synonym Full Names    fibrillin 1
 NCBI Official Symbol    FBN1 [Similar Products]
 NCBI Official Synonym Symbols   
FBN; SGS; WMS; MASS; MFS1; OCTD; SSKS; WMS2; ACMICD; ECTOL1; GPHYSD2
[Similar Products]
 NCBI Protein Information    fibrillin-1; fibrillin 15
 UniProt Protein Name    Fibrillin-1
 Protein Family    Fibrillin
 UniProt Gene Name    FBN1 [Similar Products]
 UniProt Synonym Gene Names    FBN [Similar Products]
 UniProt Entry Name    FBN1_HUMAN
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 NCBI Summary for FBN1    This gene encodes a member of the fibrillin family. The encoded protein is a large, extracellular matrix glycoprotein that serve as a structural component of 10-12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome, isolated ectopia lentis, autosomal dominant Weill-Marchesani syndrome, MASS syndrome, and Shprintzen-Goldberg craniosynostosis syndrome. [provided by RefSeq, Jul 2008]
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 UniProt Comments for FBN1    Function: Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-1-containing microfibrils provide long-term force bearing structural support. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively.1 PublicationManual assertion based on experiment in:Ref.25
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 Research Articles on FBN1    1. We propose that this marfanoid entity comprised of congenital lipodystrophy, a neonatal progeroid appearance, and a peculiar growth profile and caused by rare mutations in the penultimate exon of FBN1
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with FBN1 elisa kitPathways associated with FBN1 elisa kit
 Reference Product  PubMed Publications
 DCN elisa kit  >4 publications with FBN1 and DCN
 ELN elisa kit  >3 publications with FBN1 and ELN
 FBLN2 elisa kit  >2 publications with FBN1 and FBLN2
 ITGA5 elisa kit  >1 publications with FBN1 and ITGA5
 ITGB6 elisa kit  >1 publications with FBN1 and ITGB6
 ITGAV elisa kit  >1 publications with FBN1 and ITGAV
 MFAP5 elisa kit  >1 publications with FBN1 and MFAP5
 Products by Pathway  Pathway Diagram
 Elastic Fibre Formation Pathway antibodies  Elastic Fibre Formation Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Integrin Cell Surface Interactions Pathway antibodies  Integrin Cell Surface Interactions Pathway Diagram
Diseases associated with FBN1 elisa kitOrgans/Tissues associated with FBN1 elisa kit
 Disease Name  Pubmed Publications
 Marfan Syndrome Antibodies  >456 publications with FBN1 and Marfan Syndrome
 Cardiovascular Diseases Antibodies  >399 publications with FBN1 and Cardiovascular Diseases
 Heart Diseases Antibodies  >375 publications with FBN1 and Heart Diseases
 Ectopia Lentis Antibodies  >90 publications with FBN1 and Ectopia Lentis
 Aortic Aneurysm, Thoracic Antibodies  >58 publications with FBN1 and Aortic Aneurysm, Thoracic
 Disease Models, Animal Antibodies  >39 publications with FBN1 and Disease Models, Animal
 Arachnodactyly Antibodies  >35 publications with FBN1 and Arachnodactyly
 Aortic Rupture Antibodies  >24 publications with FBN1 and Aortic Rupture
 Nervous System Diseases Antibodies  >18 publications with FBN1 and Nervous System Diseases
 Weill-Marchesani Syndrome Antibodies  >17 publications with FBN1 and Weill-Marchesani Syndrome
 Organ/Tissue Name  Pubmed Publications
 Connective Tissue Antibodies  >175 publications with FBN1 and Connective Tissue
 Vascular Antibodies  >65 publications with FBN1 and Vascular
 Skin Antibodies  >48 publications with FBN1 and Skin
 Heart Antibodies  >43 publications with FBN1 and Heart
 Muscle Antibodies  >34 publications with FBN1 and Muscle
 Eye Antibodies  >29 publications with FBN1 and Eye
 Bone Antibodies  >23 publications with FBN1 and Bone
 Lung Antibodies  >16 publications with FBN1 and Lung
 Embryonic Tissue Antibodies  >10 publications with FBN1 and Embryonic Tissue
 Kidney Antibodies  >9 publications with FBN1 and Kidney
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