NP_062825.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
23,499 Da
NCBI Official Full Name
fibroblast growth factor 20
NCBI Official Synonym Full Names
fibroblast growth factor 20
NCBI Protein Information
fibroblast growth factor 20
UniProt Protein Name
Fibroblast growth factor 20
UniProt Synonym Gene Names
UniProt Entry Name
FGF20_HUMAN
NCBI Summary for FGF20
The protein encoded by this gene is a member of the fibroblast growth factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor but lacks a typical signal peptide. It is expressed in normal brain, particularly the cerebellum, and may regulate central nervous system development and function. Homodimerization of this protein was shown to regulate its receptor binding activity and concentration gradient in the extracellular matrix. Genetic variations of this gene have been associated with Parkinson disease susceptibility. [provided by RefSeq, Oct 2009]
UniProt Comments for FGF20
FGF20: Neurotrophic factor that regulates central nervous development and function. Belongs to the heparin-binding growth factors family.
Protein type: Cytokine
Chromosomal Location of Human Ortholog: 8p22
Cellular Component: extracellular region
Molecular Function: growth factor activity; fibroblast growth factor receptor binding
Biological Process: epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; inner ear receptor cell differentiation; cell-cell signaling; nerve growth factor receptor signaling pathway; positive regulation of cell proliferation; insulin receptor signaling pathway; innate immune response; regulation of cardiac muscle cell proliferation; signal transduction
Disease: Renal Hypodysplasia/aplasia 2
Research Articles on FGF20
Precautions
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Disclaimer
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Products associated with FGF20 elisa kit
Pathways associated with FGF20 elisa kit
Diseases associated with FGF20 elisa kit
Organs/Tissues associated with FGF20 elisa kit
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