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FGF3 elisa kit :: Human fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS929220
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (Limit 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog) (FGF3), ELISA Kit

 Also Known As   

Human Fibroblast growth factor 3, FGF3 ELISA Kit

 Product Synonym Names    Human Fibroblast growth factor 3 (FGF3) ELISA kit; HBGF-3; INT2; INT-2 proto-oncogene protein; V-INT2 murine mammary tumor virus integration site oncogene homolog; fibroblast growth factor 3; murine mammary tumor virus integration site 2; mouse; oncogen; fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog)
 Product Gene Name   

FGF3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 MBS929220 Testing Data    Testing Data PDF
 OMIM    gene 610706
 3D Structure    ModBase 3D Structure for P11487
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human FGF3. No significant cross-reactivity or interference between Human FGF3 and analogues was observed.
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 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
 Protein Biological Process 1    Developmental Protein
 Protein Biological Process 3    Differentiation
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of FGF3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for FGF3 purchase    MBS929220 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog) (FGF3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FGF3. The ELISA analytical biochemical technique of the MBS929220 kit is based on FGF3 antibody-FGF3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FGF3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FGF3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Typical Testing Data/Standard Curve (for reference only) of FGF3 elisa kit    FGF3 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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NCBI/Uniprot data below describe general gene information for FGF3. It may not necessarily be applicable to this product.
 NCBI GI #    4885233
 NCBI GeneID    2248
 NCBI Accession #    NP_005238.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005247.2 [Other Products]
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 UniProt Primary Accession #    P11487 [Other Products]
 UniProt Secondary Accession #    Q0VG69 [Other Products]
 UniProt Related Accession #    P11487 [Other Products]
 Molecular Weight    26,887 Da
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 NCBI Official Full Name    fibroblast growth factor 3
 NCBI Official Synonym Full Names    fibroblast growth factor 3
 NCBI Official Symbol    FGF3 [Similar Products]
 NCBI Official Synonym Symbols   
INT2; HBGF-3
[Similar Products]
 NCBI Protein Information    fibroblast growth factor 3; FGF-3; oncogene INT2; proto-oncogene Int-2; INT-2 proto-oncogene protein; heparin-binding growth factor 3; murine mammary tumor virus integration site 2, mouse; V-INT2 murine mammary tumor virus integration site oncogene homolog; fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog)
 UniProt Protein Name    Fibroblast growth factor 3
 UniProt Synonym Protein Names   
Heparin-binding growth factor 3; HBGF-3; Proto-oncogene Int-2
 Protein Family    Fibroblast growth factor
 UniProt Gene Name    FGF3 [Similar Products]
 UniProt Synonym Gene Names    INT2; FGF-3; HBGF-3 [Similar Products]
 UniProt Entry Name    FGF3_HUMAN
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 NCBI Summary for FGF3    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation. [provided by RefSeq, Jul 2008]
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 UniProt Comments for FGF3    FGF3: Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal ear development. Defects in FGF3 are a cause of deafness with labyrinthine aplasia, microtia and microdontia (LAMM); also known as congenital deafness with inner ear agenesis, microtia and microdontia. LAMM consists of a unique autosomal recessive syndrome characterized by type I microtia, microdontia, and profound congenital deafness associated with a complete absence of inner ear structures (Michel aplasia). Belongs to the heparin-binding growth factors family.

Protein type: Oncoprotein; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: Golgi apparatus; extracellular region

Molecular Function: protein binding; growth factor activity; fibroblast growth factor receptor binding

Biological Process: negative regulation of cardiac muscle development; epidermal growth factor receptor signaling pathway; anatomical structure morphogenesis; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; thymus development; nerve growth factor receptor signaling pathway; semicircular canal morphogenesis; signal transduction; cell-cell signaling; positive regulation of cell division; induction of an organ; positive regulation of cell proliferation; insulin receptor signaling pathway; innate immune response; otic vesicle formation

Disease: Deafness, Congenital, With Inner Ear Agenesis, Microtia, And Microdontia
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 Research Articles on FGF3    1. A de novo 290 kb interstitial duplication of chromosome 11q13.3 including the FGF3 and FGF4 genes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with FGF3 elisa kitPathways associated with FGF3 elisa kit
 Reference Product  PubMed Publications
 FGFR2 elisa kit  >27 publications with FGF3 and FGFR2
 FGFR1 elisa kit  >24 publications with FGF3 and FGFR1
 FGFR3 elisa kit  >20 publications with FGF3 and FGFR3
 FGFR4 elisa kit  >8 publications with FGF3 and FGFR4
 RPS2 elisa kit  >1 publications with FGF3 and RPS2
 EBNA1BP2 elisa kit  >1 publications with FGF3 and EBNA1BP2
 Products by Pathway  Pathway Diagram
 Downstream Signaling Of Activated FGFR Pathway antibodies  Downstream Signaling Of Activated FGFR Pathway Diagram
 FGFR Ligand Binding And Activation Pathway antibodies  FGFR Ligand Binding And Activation Pathway Diagram
 FGFR1 Ligand Binding And Activation Pathway antibodies  FGFR1 Ligand Binding And Activation Pathway Diagram
 FGFR1b Ligand Binding And Activation Pathway antibodies  FGFR1b Ligand Binding And Activation Pathway Diagram
 FGFR2 Ligand Binding And Activation Pathway antibodies  FGFR2 Ligand Binding And Activation Pathway Diagram
 FGFR2b Ligand Binding And Activation Pathway antibodies  FGFR2b Ligand Binding And Activation Pathway Diagram
 FRS2-mediated Cascade Pathway antibodies  FRS2-mediated Cascade Pathway Diagram
 IRS-mediated Signalling Pathway antibodies  IRS-mediated Signalling Pathway Diagram
 IRS-related Events Pathway antibodies  IRS-related Events Pathway Diagram
 Insulin Receptor Signalling Cascade Pathway antibodies  Insulin Receptor Signalling Cascade Pathway Diagram
Diseases associated with FGF3 elisa kitOrgans/Tissues associated with FGF3 elisa kit
 Disease Name  Pubmed Publications
 Skin Diseases Antibodies  >67 publications with FGF3 and Skin Diseases
 Stomatognathic Diseases Antibodies  >25 publications with FGF3 and Stomatognathic Diseases
 Embryo Loss Antibodies  >21 publications with FGF3 and Embryo Loss
 Syndrome Antibodies  >21 publications with FGF3 and Syndrome
 Neoplasm Metastasis Antibodies  >19 publications with FGF3 and Neoplasm Metastasis
 Craniofacial Abnormalities Antibodies  >11 publications with FGF3 and Craniofacial Abnormalities
 DEAFNESS, CONGENITAL, WITH INNER EAR AGENESIS, MICROTIA, AND MICRODONTIA Antibodies  >5 publications with FGF3 and DEAFNESS, CONGENITAL, WITH INNER EAR AGENESIS, MICROTIA, AND MICRODONTIA
 Cleft Palate Antibodies  >5 publications with FGF3 and Cleft Palate
 Cleft Lip Antibodies  >4 publications with FGF3 and Cleft Lip
 Liver Diseases Antibodies  >4 publications with FGF3 and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >55 publications with FGF3 and Brain
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