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FOXO1 elisa kit :: Human forkhead box O1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS701975
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (Limit 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

forkhead box O1 (FOXO1), ELISA Kit

 Also Known As   

Human forkhead box O1, FOXO1 ELISA Kit

 Product Synonym Names    Human forkhead box O1; FOXO1 ELISA Kit; FKH1; FKHR; FOXO1A; forkhead box O1A (rhabdomyosarcoma) ; forkhead homolog in rhabdomyosarcoma; forkhead; Drosophila; homolog of; in rhabdomyosarcoma; forkhead box O1
 Product Gene Name   

FOXO1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS701975 Testing Data    Testing Data PDF
 OMIM    gene 268220
 3D Structure    ModBase 3D Structure for Q12778
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human FOXO1. No significant cross-reactivity or interference between Human FOXO1 and analogues was observed.
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 Samples    Serum, plasma, Cell lysates
 Detection Range    0.156 ng/ml-10 ng/ml
 Sensitivity    0.039 ng/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
 Protein Biological Process 1    Transcription/Transcription regulation
 Protein Biological Process 3    Transcription
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of FOXO1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for FOXO1 purchase    MBS701975 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the forkhead box O1 (FOXO1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156 ng/ml-10 ng/ml in biological research samples containing FOXO1, with an estimated sensitivity of 0.039 ng/ml. The ELISA analytical biochemical technique of the MBS701975 kit is based on FOXO1 antibody-FOXO1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FOXO1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FOXO1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell lysates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Typical Testing Data/Standard Curve (for reference only) of FOXO1 elisa kit    FOXO1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS701975. Click to request current manual
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NCBI/Uniprot data below describe general gene information for FOXO1. It may not necessarily be applicable to this product.
 NCBI GI #    9257222
 NCBI GeneID    2308
 NCBI Accession #    NP_002006.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_002015.3 [Other Products]
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 UniProt Primary Accession #    Q12778 [Other Products]
 UniProt Secondary Accession #    O43523; Q5VYC7; Q6NSK6 [Other Products]
 UniProt Related Accession #    Q12778 [Other Products]
 Molecular Weight    69,662 Da
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 NCBI Official Full Name    forkhead box protein O1
 NCBI Official Synonym Full Names    forkhead box O1
 NCBI Official Symbol    FOXO1 [Similar Products]
 NCBI Official Synonym Symbols   
FKH1; FKHR; FOXO1A
[Similar Products]
 NCBI Protein Information    forkhead box protein O1; forkhead box protein O1A; forkhead, Drosophila, homolog of, in rhabdomyosarcoma
 UniProt Protein Name    Forkhead box protein O1
 UniProt Synonym Protein Names   
Forkhead box protein O1A; Forkhead in rhabdomyosarcoma
 Protein Family    Forkhead box protein
 UniProt Gene Name    FOXO1 [Similar Products]
 UniProt Synonym Gene Names    FKHR; FOXO1A [Similar Products]
 UniProt Entry Name    FOXO1_HUMAN
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 NCBI Summary for FOXO1    This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq, Jul 2008]
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 UniProt Comments for FOXO1    Function: Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts syngernistically with ATF4 to suppress osteocalcin/BGLAP activity, increasing glucose levels and triggering glucose intolerance and insulin insensitivity. Also suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP. In hepatocytes, promotes gluconeogenesis by acting together with PPARGC1A to activate the expression of genes such as IGFBP1, G6PC and PPCK1. Important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1. Promotes neural cell death. Mediates insulin action on adipose. Regulates the expression of adipogenic genes such as PPARG during preadipocyte differentiation and, adipocyte size and adipose tissue-specific gene expression in response to excessive calorie intake. Regulates the transcriptional activity of GADD45A and repair of nitric oxide-damaged DNA in beta-cells. Required for the autophagic cell death induction in response to starvation or oxidative stress in a transcription-independent manner.7 PublicationsManual assertion based on experiment in:Ref.8
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 Research Articles on FOXO1    1. These data provide evidence for an essential role of FoxO proteins in the transcription of ABCA6 in human vascular endothelial cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with FOXO1 elisa kitPathways associated with FOXO1 elisa kit
 Reference Product  PubMed Publications
 SIRT1 elisa kit  >147 publications with FOXO1 and SIRT1
 AKT1 elisa kit  >129 publications with FOXO1 and AKT1
 STAT3 elisa kit  >38 publications with FOXO1 and STAT3
 INS elisa kit  >31 publications with FOXO1 and INS
 AKT2 elisa kit  >27 publications with FOXO1 and AKT2
 SKP2 elisa kit  >18 publications with FOXO1 and SKP2
 CDK2 elisa kit  >14 publications with FOXO1 and CDK2
 CREBBP elisa kit  >4 publications with FOXO1 and CREBBP
 UBC elisa kit  >2 publications with FOXO1 and UBC
 FHL2 elisa kit  >2 publications with FOXO1 and FHL2
 Products by Pathway  Pathway Diagram
 AGE/RAGE Pathway antibodies  AGE/RAGE Pathway Diagram
 AKT Phosphorylates Targets In The Nucleus Pathway antibodies  AKT Phosphorylates Targets In The Nucleus Pathway Diagram
 AKT-mediated Inactivation Of FOXO1A Pathway antibodies  AKT-mediated Inactivation Of FOXO1A Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
 Angiopoietin Receptor Tie2-mediated Signaling Pathway antibodies  Angiopoietin Receptor Tie2-mediated Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
Diseases associated with FOXO1 elisa kitOrgans/Tissues associated with FOXO1 elisa kit
 Disease Name  Pubmed Publications
 Insulin Resistance Antibodies  >274 publications with FOXO1 and Insulin Resistance
 Rhabdomyosarcoma, Alveolar Antibodies  >182 publications with FOXO1 and Rhabdomyosarcoma, Alveolar
 Nervous System Diseases Antibodies  >126 publications with FOXO1 and Nervous System Diseases
 Inflammation Antibodies  >103 publications with FOXO1 and Inflammation
 Fatty Liver Antibodies  >96 publications with FOXO1 and Fatty Liver
 Hyperglycemia Antibodies  >95 publications with FOXO1 and Hyperglycemia
 Cardiovascular Diseases Antibodies  >92 publications with FOXO1 and Cardiovascular Diseases
 Liver Diseases Antibodies  >92 publications with FOXO1 and Liver Diseases
 Necrosis Antibodies  >90 publications with FOXO1 and Necrosis
 Brain Diseases Antibodies  >52 publications with FOXO1 and Brain Diseases
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >320 publications with FOXO1 and Muscle
 Liver Antibodies  >246 publications with FOXO1 and Liver
 Blood Antibodies  >235 publications with FOXO1 and Blood
 Nerve Antibodies  >191 publications with FOXO1 and Nerve
 Vascular Antibodies  >100 publications with FOXO1 and Vascular
 Pancreas Antibodies  >97 publications with FOXO1 and Pancreas
 Brain Antibodies  >94 publications with FOXO1 and Brain
 Heart Antibodies  >64 publications with FOXO1 and Heart
 Bone Antibodies  >54 publications with FOXO1 and Bone
 Embryonic Tissue Antibodies  >47 publications with FOXO1 and Embryonic Tissue
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