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FZD7 elisa kit :: Human frizzled homolog 7 (Drosophila) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9339932 FZD7 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

frizzled homolog 7 (Drosophila) (FZD7), ELISA Kit

 Also Known As   

Human Frizzled-7, FZD7 ELISA Kit

 Product Synonym Names    Human Frizzled-7 (FZD7) ELISA kit; FzE3; Frizzled; drosophila; homolog of; 7; frizzled 7; frizzled homolog 7 (Drosophila)
 Product Gene Name   

FZD7 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    603410
 3D Structure    ModBase 3D Structure for O75084
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of FZD7 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for FZD7 purchase    MBS9339932 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the frizzled homolog 7 (Drosophila) (FZD7) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FZD7. The ELISA analytical biochemical technique of the MBS9339932 kit is based on FZD7 antibody-FZD7 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FZD7 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FZD7. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for FZD7. It may not necessarily be applicable to this product.
 NCBI GI #    4503833
 NCBI GeneID    8324
 NCBI Accession #    NP_003498.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_003507.1 [Other Products]
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 UniProt Primary Accession #    O75084 [Other Products]
 UniProt Secondary Accession #    O94816; Q53S59; Q96B74 [Other Products]
 UniProt Related Accession #    O75084 [Other Products]
 Molecular Weight    63,620 Da
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 NCBI Official Full Name    frizzled-7
 NCBI Official Synonym Full Names    frizzled class receptor 7
 NCBI Official Symbol    FZD7 [Similar Products]
 NCBI Official Synonym Symbols   
FzE3
[Similar Products]
 NCBI Protein Information    frizzled-7; fz-7; hFz7; frizzled homolog 7; frizzled family receptor 7; Frizzled, drosophila, homolog of, 7; frizzled 7, seven transmembrane spanning receptor
 UniProt Protein Name    Frizzled-7
 UniProt Synonym Protein Names   
FzE3
 Protein Family    Frizzled
 UniProt Gene Name    FZD7 [Similar Products]
 UniProt Synonym Gene Names    Fz-7; hFz7 [Similar Products]
 UniProt Entry Name    FZD7_HUMAN
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 NCBI Summary for FZD7    Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008]
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 UniProt Comments for FZD7    FZD7: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK- 3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Belongs to the G-protein coupled receptor Fz/Smo family.

Protein type: Receptor, GPCR; GPCR, Fz/Smo family; Membrane protein, multi-pass; Motility/polarity/chemotaxis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q33

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; Wnt-protein binding; protein binding; Wnt receptor activity; frizzled binding; PDZ domain binding

Biological Process: neuron differentiation; G-protein coupled receptor protein signaling pathway; regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; positive regulation of epithelial cell proliferation involved in wound healing; stem cell maintenance; T cell differentiation in the thymus; positive regulation of JNK cascade; somatic stem cell division; Wnt receptor signaling pathway through beta-catenin; satellite cell compartment self-renewal involved in skeletal muscle regeneration; negative regulation of ectodermal cell fate specification; positive regulation of phosphorylation
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 Research Articles on FZD7    1. results demonstrate that FZD7 encodes a regulator of the pluripotent state and that hESCs require endogenous WNT/beta-catenin signaling through FZD7 to maintain an undifferentiated phenotype
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with FZD7 elisa kitDiseases associated with FZD7 elisa kit
 Products by Pathway  Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Melanogenesis Pathway antibodies  Melanogenesis Pathway Diagram
 Melanogenesis Pathway antibodies  Melanogenesis Pathway Diagram
 Noncanonical Wnt Signaling Pathway antibodies  Noncanonical Wnt Signaling Pathway Diagram
 Pathways In Cancer antibodies  Pathways In Cancer Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >39 publications with FZD7 and Neoplasms
 Carcinoma Antibodies  >16 publications with FZD7 and Carcinoma
 Intestinal Diseases Antibodies  >13 publications with FZD7 and Intestinal Diseases
 Liver Neoplasms Antibodies  >9 publications with FZD7 and Liver Neoplasms
 Adenocarcinoma Antibodies  >9 publications with FZD7 and Adenocarcinoma
 Liver Diseases Antibodies  >8 publications with FZD7 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >8 publications with FZD7 and Carcinoma, Hepatocellular
 Breast Neoplasms Antibodies  >4 publications with FZD7 and Breast Neoplasms
 Neoplasm Metastasis Antibodies  >4 publications with FZD7 and Neoplasm Metastasis
 Skin Diseases Antibodies  >4 publications with FZD7 and Skin Diseases
Organs/Tissues associated with FZD7 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >26 publications with FZD7 and Embryonic Tissue
 Liver Antibodies  >12 publications with FZD7 and Liver
 Brain Antibodies  >9 publications with FZD7 and Brain
 Kidney Antibodies  >8 publications with FZD7 and Kidney
 Stomach Antibodies  >7 publications with FZD7 and Stomach
 Bone Antibodies  >7 publications with FZD7 and Bone
 Lung Antibodies  >6 publications with FZD7 and Lung
 Muscle Antibodies  >5 publications with FZD7 and Muscle
 Connective Tissue Antibodies  >4 publications with FZD7 and Connective Tissue
 Eye Antibodies  >4 publications with FZD7 and Eye
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