NP_000141.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
41,860 Da
NCBI Official Full Name
alpha-(1,3)-fucosyltransferase 6
NCBI Official Synonym Full Names
fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
NCBI Protein Information
alpha-(1,3)-fucosyltransferase 6; alpha-(1,3)-fucosyltransferase 6; fucosyltransferase VI; galactoside 3-L-fucosyltransferase
UniProt Protein Name
Alpha-(1,3)-fucosyltransferase 6
UniProt Synonym Protein Names
Fucosyltransferase 6; Fucosyltransferase VI; Fuc-TVI; FucT-VI; Galactoside 3-L-fucosyltransferase
UniProt Synonym Gene Names
UniProt Entry Name
FUT6_HUMAN
NCBI Summary for FUT6
The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of sialyl-Lewis X, an E-selectin ligand. Mutations in this gene are a cause of fucosyltransferase-6 deficiency. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for FUT6
FUT6: Enzyme involved in the biosynthesis of the E-Selectin ligand, sialyl-Lewis X. Catalyzes the transfer of fucose from GDP- beta-fucose to alpha-2,3 sialylated substrates. Belongs to the glycosyltransferase 10 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transferase; EC 2.4.1.65; Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; Membrane protein, integral
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: Golgi apparatus; integral to membrane
Molecular Function: 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity; alpha(1,3)-fucosyltransferase activity; fucosyltransferase activity
Biological Process: protein amino acid glycosylation; L-fucose catabolic process
Disease: Fucosyltransferase 6 Deficiency
Research Articles on FUT6
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with FUT6 elisa kit
Diseases associated with FUT6 elisa kit
Organs/Tissues associated with FUT6 elisa kit
|