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GJA8 elisa kit :: Human gap junction protein, alpha 8, 50kDa ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9329654 GJA8 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

gap junction protein, alpha 8, 50kDa (GJA8), ELISA Kit

 Also Known As   

Human Gap junction alpha-8 protein, GJA8 ELISA Kit

 Product Synonym Names    Human Gap junction alpha-8 protein (GJA8) ELISA kit; CAE; CAE1; CX50; CZP1; MP70; OTTHUMP00000025757; cell surface glycoprotein; connexin 50; gap junction membrane channel protein alpha-8; lens fiber protein MP70; lens intrinsic membrane protein MP70; gap junction protein; alpha 8; 50kDa
 Product Gene Name   

GJA8 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    600897
 3D Structure    ModBase 3D Structure for P48165
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of GJA8 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for GJA8 purchase    MBS9329654 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the gap junction protein, alpha 8, 50kDa (GJA8) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GJA8. The ELISA analytical biochemical technique of the MBS9329654 kit is based on GJA8 antibody-GJA8 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GJA8 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GJA8. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for GJA8. It may not necessarily be applicable to this product.
 NCBI GI #    55953076
 NCBI GeneID    2703
 NCBI Accession #    NP_005258.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_005267.4 [Other Products]
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 UniProt Primary Accession #    P48165 [Other Products]
 UniProt Secondary Accession #    Q5VVN9; Q9NP25; A7L5M5 [Other Products]
 UniProt Related Accession #    P48165 [Other Products]
 Molecular Weight    48,229 Da
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 NCBI Official Full Name    gap junction alpha-8 protein
 NCBI Official Synonym Full Names    gap junction protein, alpha 8, 50kDa
 NCBI Official Symbol    GJA8 [Similar Products]
 NCBI Official Synonym Symbols   
CAE; CAE1; CX50; CZP1; MP70; CTRCT1
[Similar Products]
 NCBI Protein Information    gap junction alpha-8 protein; connexin 50; connexin-50; lens fiber protein MP70; cell surface glycoprotein; gap junction protein alpha 8 50kDa; lens intrinsic membrane protein MP70; gap junction membrane channel protein alpha-8
 UniProt Protein Name    Gap junction alpha-8 protein
 UniProt Synonym Protein Names   
Connexin-50; Cx50; Lens fiber protein MP70
 Protein Family    Gap junction alpha-8 protein
 UniProt Gene Name    GJA8 [Similar Products]
 UniProt Synonym Gene Names    Cx50 [Similar Products]
 UniProt Entry Name    CXA8_HUMAN
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 NCBI Summary for GJA8    This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome. [provided by RefSeq, Dec 2009]
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 UniProt Comments for GJA8    GJA8: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins. This particular connexin only forms junctional channels. Eye lens. Belongs to the connexin family. Alpha-type (group II) subfamily.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Channel, misc.

Chromosomal Location of Human Ortholog: 1q21.1

Cellular Component: connexon complex; integral to plasma membrane

Molecular Function: channel activity; gap junction channel activity

Biological Process: lens development in camera-type eye; visual perception; cell-cell signaling; transport; transmembrane transport; protein homooligomerization

Disease: Cataract 1, Multiple Types
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 Research Articles on GJA8    1. The results provide a molecular basis for the formation of various cataract phenotypes in human patients with Cx50 mutations.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with GJA8 elisa kitPathways associated with GJA8 elisa kit
 Reference Product  PubMed Publications
 MIP elisa kit  >7 publications with GJA8 and MIP
 Products by Pathway  Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Gap Junction Assembly Pathway antibodies  Gap Junction Assembly Pathway Diagram
 Gap Junction Trafficking Pathway antibodies  Gap Junction Trafficking Pathway Diagram
 Gap Junction Trafficking And Regulation Pathway antibodies  Gap Junction Trafficking And Regulation Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
Diseases associated with GJA8 elisa kitOrgans/Tissues associated with GJA8 elisa kit
 Disease Name  Pubmed Publications
 Cataract Antibodies  >58 publications with GJA8 and Cataract
 CATARACT, ZONULAR PULVERULENT 1 Antibodies  >2 publications with GJA8 and CATARACT, ZONULAR PULVERULENT 1
 CATARACT, NUCLEAR PROGRESSIVE Antibodies  >2 publications with GJA8 and CATARACT, NUCLEAR PROGRESSIVE
 Cataract microcornea syndrome Antibodies  >2 publications with GJA8 and Cataract microcornea syndrome
 Atrial Fibrillation Antibodies  >1 publications with GJA8 and Atrial Fibrillation
 Skin Diseases Antibodies  >1 publications with GJA8 and Skin Diseases
 Fibrosarcoma Antibodies  >1 publications with GJA8 and Fibrosarcoma
 Chromosome Aberrations Antibodies  >1 publications with GJA8 and Chromosome Aberrations
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >50 publications with GJA8 and Eye
 Brain Antibodies  >1 publications with GJA8 and Brain
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