NP_004119.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
28,380 Da
NCBI Official Full Name
general transcription factor IIF subunit 2
NCBI Official Synonym Full Names
general transcription factor IIF, polypeptide 2, 30kDa
NCBI Protein Information
general transcription factor IIF subunit 2; TFIIF-beta; ATP-dependent helicase GTF2F2; transcription initiation factor RAP30; general transcription factor IIF 30 kDa subunit; transcription initiation factor IIF subunit beta
UniProt Protein Name
General transcription factor IIF subunit 2
UniProt Synonym Protein Names
ATP-dependent helicase GTF2F2; General transcription factor IIF 30 kDa subunit; Transcription initiation factor IIF subunit beta; TFIIF-beta; Transcription initiation factor RAP30
UniProt Synonym Gene Names
UniProt Entry Name
T2FB_HUMAN
UniProt Comments for GTF2F2
GTF2F2: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA- helicase activity. Belongs to the TFIIF beta subunit family.
Protein type: Nuclear receptor co-regulator; Helicase; Transcription initiation complex; EC 3.6.4.12
Chromosomal Location of Human Ortholog: 13q14
Cellular Component: microtubule cytoskeleton; nucleoplasm; transcription factor TFIIF complex; nucleus
Molecular Function: protein binding; DNA binding; ATP-dependent helicase activity; ATP binding
Biological Process: nuclear mRNA splicing, via spliceosome; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; mRNA capping; regulation of transcription, DNA-dependent; viral reproduction; positive regulation of viral transcription; RNA splicing; RNA elongation from RNA polymerase II promoter; gene expression
Research Articles on GTF2F2
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Pathways associated with GTF2F2 elisa kit
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