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GRIK1 elisa kit :: Human glutamate receptor (NMDAR) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2602961 GRIK1 elisa kit
Unit / Price
48-Strip-Wells  /  $260 +1 FREE 8GB USB
96-Strip-Wells  /  $405 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,615 +2 FREE 8GB USB
10x96-Strip-Wells  /  $2,880 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

glutamate receptor (NMDAR) (GRIK1), ELISA Kit

 Also Known As   

Human glutamate receptor, NMDAR ELISA Kit

 Product Gene Name   

GRIK1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    138245
 3D Structure    ModBase 3D Structure for P39086
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of GRIK1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for GRIK1 purchase    MBS2602961 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the glutamate receptor (NMDAR) (GRIK1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GRIK1. The ELISA analytical biochemical technique of the MBS2602961 kit is based on GRIK1 antibody-GRIK1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GRIK1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GRIK1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Sample Manual Insert of MBS2602961. Click to request current manual
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NCBI/Uniprot data below describe general gene information for GRIK1. It may not necessarily be applicable to this product.
 NCBI GI #    4154321
 NCBI GeneID    2897
 NCBI Accession #    AAD04931.1 [Other Products]
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 UniProt Primary Accession #    P39086 [Other Products]
 UniProt Secondary Accession #    Q13001; Q86SU9 [Other Products]
 UniProt Related Accession #    P39086 [Other Products]
 Molecular Weight    102,631 Da [Similar Products]
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 NCBI Official Full Name    glutamate receptor, partial
 NCBI Official Synonym Full Names    glutamate receptor, ionotropic, kainate 1
 NCBI Official Symbol    GRIK1 [Similar Products]
 NCBI Official Synonym Symbols   
EAA3; EEA3; GLR5; GLUR5; GluK1
[Similar Products]
 NCBI Protein Information    glutamate receptor ionotropic, kainate 1; gluR-5; glutamate receptor 5; excitatory amino acid receptor 3
 UniProt Protein Name    Glutamate receptor ionotropic, kainate 1
 UniProt Synonym Protein Names   
Excitatory amino acid receptor 3; EAA3; Glutamate receptor 5; GluR-5; GluR5
 Protein Family    Glutamate receptor ionotropic
 UniProt Gene Name    GRIK1 [Similar Products]
 UniProt Synonym Gene Names    GLUR5; GluK1; EAA3; GluR-5; GluR5 [Similar Products]
 UniProt Entry Name    GRIK1_HUMAN
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 NCBI Summary for GRIK1    Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for GRIK1    GluR5: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK1 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Channel, ligand-gated

Chromosomal Location of Human Ortholog: 21q22.11

Cellular Component: presynaptic membrane; postsynaptic membrane; kainate selective glutamate receptor complex; integral to plasma membrane; dendrite; plasma membrane; cell junction

Molecular Function: kainate selective glutamate receptor activity; extracellular-glutamate-gated ion channel activity

Biological Process: nervous system development; synaptic transmission, glutamatergic; regulation of synaptic transmission, glutamatergic; central nervous system development; glutamate signaling pathway; positive regulation of synaptic transmission, GABAergic; negative regulation of synaptic transmission, glutamatergic; regulation of inhibitory postsynaptic membrane potential; synaptic transmission; behavioral response to pain; transport; ionotropic glutamate receptor signaling pathway; adult behavior; regulation of excitatory postsynaptic membrane potential; positive regulation of gamma-aminobutyric acid secretion
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 Research Articles on GRIK1    1. Topiramate treatment for alcohol dependence was significantly more effective in rs2832407 C-allele homozygotes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with GRIK1 elisa kitPathways associated with GRIK1 elisa kit
 Reference Product  PubMed Publications
 BDNF elisa kit  >2 publications with GRIK1 and BDNF
 DLG4 elisa kit  >1 publications with GRIK1 and DLG4
 GRIP1 elisa kit  >1 publications with GRIK1 and GRIP1
 Products by Pathway  Pathway Diagram
 Activation Of Ca-permeable Kainate Receptor Pathway antibodies  Activation Of Ca-permeable Kainate Receptor Pathway Diagram
 Activation Of Kainate Receptors Upon Glutamate Binding Pathway antibodies  Activation Of Kainate Receptors Upon Glutamate Binding Pathway Diagram
 Activation Of Na-permeable Kainate Receptors Pathway antibodies  Activation Of Na-permeable Kainate Receptors Pathway Diagram
 Glutamatergic Synapse Pathway antibodies  Glutamatergic Synapse Pathway Diagram
 Glutamatergic Synapse Pathway antibodies  Glutamatergic Synapse Pathway Diagram
 Ionotropic Activity Of Kainate Receptors Pathway antibodies  Ionotropic Activity Of Kainate Receptors Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuronal System Pathway antibodies  Neuronal System Pathway Diagram
 Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Pathway antibodies  Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Pathway Diagram
Diseases associated with GRIK1 elisa kitOrgans/Tissues associated with GRIK1 elisa kit
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >6 publications with GRIK1 and Nervous System Diseases
 Epilepsy Antibodies  >5 publications with GRIK1 and Epilepsy
 Brain Diseases Antibodies  >4 publications with GRIK1 and Brain Diseases
 Central Nervous System Diseases Antibodies  >4 publications with GRIK1 and Central Nervous System Diseases
 Pain Antibodies  >2 publications with GRIK1 and Pain
 Learning Disorders Antibodies  >2 publications with GRIK1 and Learning Disorders
 Seizures Antibodies  >2 publications with GRIK1 and Seizures
 Anxiety Disorders Antibodies  >1 publications with GRIK1 and Anxiety Disorders
 Memory Disorders Antibodies  >1 publications with GRIK1 and Memory Disorders
 Inflammation Antibodies  >1 publications with GRIK1 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >6 publications with GRIK1 and Brain
 Embryonic Tissue Antibodies  >1 publications with GRIK1 and Embryonic Tissue
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